Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 326 for “"kidney disease"”.
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Economic studies of chronic kidney disease
… 9% of the global population has chronic kidney disease (CKD). Patients with end-stage renal disease (ESRD), the most advanced form of CKD, comprise 0.15% of the global population but consume 2-4% healthcare budgets. While the impact of CKD and ESRD are experienced most immediately by …
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Dietary phosphorus in chronic kidney disease
… is common in the later stages of chronic kidney disease and is a universal problem in end stage kidney disease, where it is associated with increased morbidity and mortality. Treatment includes a low phosphorus diet, that imposes numerous dietary restrictions, lacks a robust evidence base …
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Molecular diagnosis in inherited polycystic kidney disease
Polycystic Kidney Disease (PKD) incorporates a number of genetically but not always phenotypically distinct inherited cystic kidney disorders. Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most frequent, with an estimated prevalence of 1:1000. Though common, there are numerous …
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Cardiovascular Functional Alterations in Chronic Kidney Disease
Cardiovascular disease is a major life-limiting complication in patients with Chronic Kidney Disease (CKD). The development of cardiovascular disease during renal impairment involves striking multitiered, multi-dimensional complex alterations encompassing the entire oxygen transport system. Complex …
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Development of Therapies to Treat Polycystic Kidney Disease
Polycystic kidney diseases (PKD) are genetic disorders characterized by fluid filled cysts in the kidney tubules and liver bile ducts. There are two forms of PKD, autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD). The focus of the studies …
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Characterization of Understudied Risk Factors in Chronic Kidney Disease
Chronic kidney disease (CKD) is a major global health concern and is increasingly recognized as a leading cause of mortality. Furthermore, environmental causes of CKD are being acknowledged as this contributes to CKD of unknown etiology (CKDu), which is becoming an increasing burden in developing …
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The role of diet therapy in chronic kidney disease
Background Chronic kidney disease (CKD) is a condition characterized by gradual loss of kidney function over time. Millions of adults have CKD and those who have diabetes, hypertension, and family history of kidney failure are at highest risk of its development. Patients may develop comorbidities, …
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Mechanisms underlying progressive nephron injury in chronic kidney disease
Includes bibliographical references.
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Targeting Glutamine Metabolism in Kidney Development and Polycystic Kidney Disease
Polycystic kidney disease is a hereditary disorder characterized by the progressive manifestation of numerous fluid-filled sacs, known as cysts, within the renal epithelia. The enlargement of the cysts causes the gradual replacement of normal kidney parenchyma which leads to impairment of renal …
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Olfactory identification, detection thresholds, and sensitivity in kidney disease patients
… identification scores for patients with Kidney Disease, there are contradictory results for detection thresholds. Some results indicate higher thresholds while others found similar thresholds or elevated thresholds for one odorant, but not others. The current study evaluated the olfactory …
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Identification and evaluation of novel biomarkers in diabetic kidney disease
Introduction: Diabetic kidney disease (DKD) is a progressive microvascular complication that leads to a decline in renal function and is the most frequent cause of end-stage renal disease. Currently, there is a need for improved biomarkers for the early detection of DKD. microRNAs (miRNAs) are …
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Chronic kidney disease : comparing trends in primary and secondary care
Background Chronic kidney disease is a serious and complex medical condition which affects a significant number of people in the UK. Guidance from NICE currently recommends referral of CKD patients at stages G4-5 but the guidelines themselves are not based on strong evidence. Objectives To compare …
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ROLE OF THE Na,K-ATPase IN POLYCYSTIC KIDNEY DISEASE
Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic disease, and is characterized by multiple fluid-filled cysts that impair the organ, ultimately leading to renal failure. Formation and enlargement of the cysts require abnormal proliferation and cell death, as well as …
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Interactions Between Aging and Chronic Kidney Disease on the Skeleton
In the US, 15% of adults have chronic kidney disease (CKD). While CKD occurs across all ages, the prevalence is highest in the aged, with ~40% of individuals over age 65 having some form of CKD. CKD and aging are each independently associated with higher fracture risk, and thus overlaying CKD in …
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The spectrum of HIV-related kidney disease in South Africa
The spectrum of HIV-related kidney disease in South Africa Associate Professor Nicola Wearne Background: HIV is associated with a spectrum of kidney diseases, including HIV-associated nephropathy (HIVAN), opportunistic infections, including tuberculosis (TB), and adverse effects of drugs and immune …
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component of metabolic syndrome and relation with chronic kidney disease
본 연구는 대사증후군의 구성 요소들의 조합에 따른 만성신질환 관계를 보고자 한다. 본 연구를 위하여 국민 건강영양조사 제 5기의 2010, 2011, 2012년 데이터를 사용하였다. 데이터에서 조사 대상자는 총 25,534명 중 20 세 이상인 19,185명을 대상으로 하였다. 대사증후군을 가진 사람들의 대사증후군 요소들의 각 조합에 따른 만성신질환의 분포를 비교하였고, 다른 변수를 통제하고, 만성신질환과의 관련성을 보았다. 20세 이상 성인 대상자 중 연령증가, 기혼, 교육수준이 높고, 소득이 낮으며, 무직일 경우 대사증후군이 …
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Assessing Disease Modifying Therapies in Autosomal Dominant Polycystic Kidney Disease
… cyst growth in autosomal dominant polycystic kidney disease (ADPKD) and is a key therapeutic target. Evaluation of high water intake (HWI) as an alternative to pharmacological vasopressin blockade is supported by patients. However the feasibility, safety and adherence-promoting strategies …
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Early Outgrowth Cells As A Novel Therapy for Chronic Kidney Disease
Chronic kidney disease (CKD) and its cardiac complications represent a large and growing problem in Canada. The progression of CKD is driven by the activation of several final common pathways of injury, including fibrosis and oxidative stress. If left unchecked, these inter-connected processes lead …
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