Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"keto acids"”.
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Metabolic engineering aimed at the production of keto acids from glycerol : an industrial by-product
… at the enhanced formation of pyruvate and α-ketoglutarate (KG). Under the influence of H2O2, P. fluorescens engineers an intricate metabolic network to synthesize ATP and pyruvate. As oxidative phosphorylation is severely impeded, the microbe invokes substrate level phosphorylation to …
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The Oxidative Deamination of Sulfur Amino Acids by a Bacterial L-Amino Acid Oxidase
<p>The oxidative deamination of sulfur amino acids by a particulate L-amino acid oxidase obtained from an atypical Proteus rettgeri has been investigated. In addition to several sulfur amino acids tested here the enzyme catalyzes the oxidation of L-leucine, L-phenylalanine, L-tryptophan, …
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Investigation of regulatory and functional diversity in an enzyme superfamily
… condensation of acetyl-CoA with six different -keto acids. While some sequentially similar members of this subgroup exhibit distinct substrate specificities, some members with low sequence identities display identical activities. Though the underlying causes of these phenomena are still unknown, …
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Investigation of the Evolutionary Aspects of Thiamin Diphosphate-Dependent Decarboxylases
… oxidative and nonoxidative decarboxylation of 2-keto acids, carboligation reactions, the cleavage of C-C bonds, and the formation of C-S, C-N, and C-O bonds. Surprisingly, given this diversity, all ThDP-dependent enzyme catalyzed reactions proceed through essentially the same intermediate. This …
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The application of silica-alumina catalysts to a Friedel-Crafts type reaction
… such as the preparation of hydrocarbons, keto acids, acids, ketones, and phenols. Halides of iron, tin, phosphorus, zinc, and other metals, and acids such as phosphoric, sulfuric, and anhydrous hydrofluoric have been found to catalyze a large number of reactions of this type. These same …
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Mechanistic Studies of Flavin-Dependent Monooxygenases Involved in Bacterial Defense and Plant Metabolism
… only have steady-state activity with aromatic α-keto acids indole-3-pyruvic acid (IPA) and phenylpyruvic acid (PPA). We also propose that a C4a-peroxyflavin intermediate acts as a nucleophile to perform the oxidative decarboxylation on IPA and PPA. The work in this dissertation fills several …
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Characterization of the branched chain α-ketoacid dehydrogenase complex
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Identification and characterization of virulence associated factors of C. jejuni
… able to metabolize products like free amino and keto acids that have been generated by these bacterial species or from the host himself.In order to identify genes which are related to the invasion of host cells by the pathogen, 660 clones of a transposon mutant library generated in the clinical …
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Role of Hydroxy acid oxidase 2 (Hao2) in hepatocellular carcinoma
… capable of oxidizing a broad range of 2-hydroxy acids, ranging from glycolate to long chain 2-hydroxy fatty acids, such as 2-hydroxypalmitate, to 2-keto acids; this reaction results in hydrogen peroxide (H2O2) formation at the expense of molecular oxygen. Aim: Since no data concerning Hao2, a …
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Characterization of an extremely thermophilic, anaerobic sulphur-dependent archaebacterium
… In the presence of peptone, several amino acids, α-keto acids, glucose, lactose, casein, and starch stimulate growth. Sodium and sulphur are required for growth. Sodium can be replaced by lithium and sulphur by cystine and glutathione. Sodium is required for utilization of several amino …
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THE APPLICATION OF OXIDATIVE HYDROTHERMAL DISSOLUTION (OHD) TO ORGANIC-RICH SHALES
… a complex mixture of aliphatic carboxylic acids, dicarboxylic acids, keto-acids, aromatic acids, and poly-acids, some of which include phenolic structures. These products include materials that are useful as chemical feedstocks for the manufacture of plasticizers, nylons, polymers, …
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Towards the Synthesis of Magnesidin
… intermediates necessary for the synthesis as β- keto esters, α,β-unsaturated amino esters. The focus of the work has been addressed by developing a TAG molecule approach, which is similar to the concept of solid phase synthesis except for the fact that the TAG molecule can be identified under UV …