Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"keratinocyte growth factor"”.
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KGF-1 and KGF receptor expression in human periodontal disease and in vitro microwounding-associated-ligand-independent KGFR activation
… resulting in periodontal attachment loss. Keratinocyte Growth Factor-1 (KGF-1) is upregulated in chronic inflammation and specifically stimulates epithelial cell proliferation by signaling through the epithelial-specific Keratinocyte Growth Factor Receptor (KGFR). First, we examined KGF-1 …
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An alginate hydrogel matrix for the localised delivery of a fibroblast/ keratinocyte co-culture to expedite wound healing
… in calcium-alginate hydrogel and culture of keratinocytes on the surface. Initially, the use of 5% and 2% w/v alginate hydrogels were investigated. Both scaffolds maintained fibroblast viability for at least 150 days encapsulation and caused reversible mitotic and catabolic inhibition, as …
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The role of mucus in the cross talk between gut bacteria and the host
… cells from TCRδ-/- mice showed, upon addition of keratinocyte growth factor, increases in crypt length, and both goblet cell numbers and redistribution. These findings provide novel mechanisms by which γδ IELs may modulate mucus properties, explaining the increased susceptibility of TCRδ-/- mice …
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Investigation of the role of antagonism of the Interleukin-7 Receptor in the treatment of Multiple Sclerosis in Humans and In Vitro differences between genetically stratified subjects based on Interleukin-7 Receptor Genotype
… 5 investigated the tolerability of palifermin, a keratinocyte growth factor, with alemtuzumab, which was well tolerated as part of a dose escalation sub-study of the CAMTHY trial. The main CAMTHY trial investigated if palifermin could cause increased thymic lymphopoiesis, offsetting the IL-7 …
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Experimentelle Untersuchung zur Wirkung von in Tumorzellen produziertem Keratinozytenwachstumsfaktor (KGF) auf die proliferative Aktivität und Strahlenreaktion von Tumoren und Normalgewebe
In der vorliegenden Arbeit wurde die Wirkung von rHuKGF (Palifermin) und von Tumoren produzierten KGF auf die proliferative Aktivität und Strahlensensibilität von epithelialen Tumoren und Keratinozyten in vitro untersucht. Es wurde die Wirkung auf vier epitheliale Tumorzelllinien von …