Global ETD Search
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Showing 1 to 5 of 5 for “"katanin"”.
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Co-orthologs of KATANIN1 Impact Plant Morphology and Show Differential Evolution in Maize
… A microtubule-severing enzyme called katanin p60 is encoded by KATANIN1 (KTN1) in Arabidopsis or by an ortholog, dwarf and gladius leaf1 (dgl1), in rice. Katanin p60 has been implicated in the control of anisotropic cell growth, which is cell growth directed in a specific direction …
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Spindle organization in three dimensions
… the role of the microtubule severing complex katanin in spindle organization was analyzed. Electron tomography reveals fragmentation of spindle microtubules and suggests a novel katanin-dependent mechanism of meiotic spindle assembly. In this model, relatively long microtubules seen near the …
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Using Small Molecule Tools to Study ATPase Mechanoenzymes
… AAA domain of the microtubule severing protein katanin, and the identification of a druggable site for chemical activators in valosin-containing protein (VCP)/p97, a AAA unfoldase whose loss of function has been linked to protein aggregation-based disorders. For the chemical genetics approach, …
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Modelling the formation of ordered acentrosomal microtubule arrays
… below 0.5. We�find that the severing action of katanin is able to restore order at CIC probabilities below 0.5 but the speed at which crossovers must be severed becomes unfeasibly fast as the CIC decreases. This implies that at very low CICs observed in nature (�0.1), katanin may be necessary …
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Microtubules, Acetylation, and MEC-3 Regulated Genes in C. Elegans Mechanosensations
… the C. elegans homolog of the MT severing enzyme katanin, and several other proteins. I also shed light on the significance of á-tubulin acetylation by investigating the acetyltransferases responsible. MEC-17 and ATAT-2 are á-tubulin acetyltransferases found in the TRNs, which illustrate …