Global ETD Search
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Showing 1 to 2 of 2 for “"karyotype heterogeneity"”.
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Tracking profiles of genomic instability in spontaneous transformation and tumorigenesis
… the current data emphasize the significance of karyotype heterogeneity in cancer progression over specific gene-based causes of cancer. Variability of a magnitude significant to shift cell populations from homogeneous diploid cells to a mosaic of structural and numerical chromosome alterations …
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The evolution of centrosome and chromosome number in newly formed tetraploid human cells
… dynamics. Next, I investigate karyotypic heterogeneity in newly formed tetraploid cells and their counterparts that are grown for 12 days under standard culture conditions and find that karyotypic heterogeneity has increased after 12 days of growth after tetraploidization. The day 12 …