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Showing 1 to 20 of 62 for “"joint disease"”.
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Bone Marrow Mononuclear Cell for Equine Joint Disease
… radiographic evidence of moderate OA in a single joint were randomly assigned to 1 of 3 treatments: saline (negative control), triamcinolone (positive control), or BMNC (treatment group). Horses were subjectively and objectively evaluated for lameness and synovial fluid collected (cytology and …
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Recombinant Equine Interleukin-1 Induced Models of Equine Joint Disease
Osteoarthritis (OA) is a debilitating disease of joints that afflicts horses of all ages and breeds and can result in lameness, suboptimal performance, and decreased quality of life. The pro-inflammatory cytokine interleukin-1 (IL-1) has been associated with the initiation and pathogenesis of joint …
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Proteoglycan-4 in Equine Joint Disease, Exercise, and in vitro Cartilage Repair
… lubrication. The biological consequences of joint injury or disease such as osteoarthritis (OA) may include altered concentration, structure, and function of PRG4 and HA, leading to degraded SF quality and function, changes which are not fully understood. Furthermore, the effects of joint …
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Mseleni joint disease : a study of the clinical and radiological aspects and possible modes of inheritance
Mseleni Joint Disease is a disabling polyarticular disorder occurring with a high prevalence in the Mseleni area of Northern Zululand. During the past three years the series of epidemiological, genealogical and clinico-radiological studies carried out in the Mseleni Joint Disease Project have …
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Interleukin-1 receptor antagonist delivery through adenoviral mediated gene transfer as a treatment for equine joint disease
… it has been centrally linked to mediation of joint pathology in most species. This project was conducted to assess both ability to deliver a transgene to the joints of horses, and the specific effects overproduction of IL-1Ra using gene transfer would have on an experimental model of joint …
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Modelling the early development of cartilage and bone in Mseleni Joint Disease using induced pluripotent stem cells
Mseleni joint disease (MJD) is an unusual crippling osteoarthropathy that occurs in significant numbers of the indigenous population in a remote rural region of Northern KwaZulu Natal, South Africa. The most affected joints are the hip, and early developmental abnormalities lead to secondary …
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A Comparison Study of Vertebral Degenerative Joint Disease in the Hunter-Gatherer Population at Indian Knoll, Kentucky and Agriculturalists
… and severity of osteophytosis (degenerative joint disease) in the vertebral elements of hunter-gatherer populations and agricultural populations in order to determine whether farming or hunting and gathering places greater occupational stress on the vertebral column. It is hypothesized that …
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A Comparison Study of Vertebral Degenerative Joint Disease in the Hunter-Gatherer Population at Indian Knoll, Kentucky and Agriculturalists
… and severity of osteophytosis (degenerative joint disease) in the vertebral elements of hunter-gatherer populations and agricultural populations in order to determine whether farming or hunting and gathering places greater occupational stress on the vertebral column. It is hypothesized that …
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Socio-ecological risk factors, explanatory models and treatment-seeking behaviours associated with Mseleni joint disease: a biocultural mixed methods study
Mseleni Joint Disease (MJD) is a crippling osteoarthropathy of unknown aetiology endemic to southern African Bantu-language speakers in a remote region of Northern KwaZulu-Natal, South Africa. Effective management of MJD has been hindered by limited insight into risk factors, explanatory models or …
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A Study of the Intra-Articular Temperature, the Synovial Fluid Viscosity,and the Cellular Components in Joint Disease of the Horse
Made available in DSpace on 2014-12-09T22:30:23Z (GMT). No. of bitstreams: 1 6915371.pdf: 2922014 bytes, checksum: 62b6a6012061a99dc870716d47293e93 (MD5) Previous issue date: 1969
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Evaluation of allogeneic bone marrow-derived mesenchymal stem cells for use in equine joints: in vitro to preclinical evaluation
Joint disease is prominent in the equine population and horses provide a highly translational model for human joint disease. Mesenchymal stem cells (MSCs) have been investigated as a treatment of musculoskeletal disease in the horse with autologous MSCs showing promise as a treatment of desmitis, …
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Designing nanocarriers to penetrate cartilage and improve delivery of biologic drugs for osteoarthritis
Osteoarthritis is a debilitating joint disease that affects over 30 million people and has no disease-modifying therapies. The current standard of care for the disease is merely palliative until joint replacement is necessary. Disease-modifying osteoarthritis drugs have been tested in the clinic, …
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Comparison of healing of full-thickness cartilage vs. full- thickness cartilage and subchondral bone defects in the equine third carpal bone
… layer of fibrous connective tissue. Degenerative joint disease occurred in all joints. Results were similar between four- and six-month specimens. Further studies are needed before removal of the subchondral bone plate can be recommended for clinical treatment of full-thickness articular cartilage …
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A Comprehensive Case Report of University of Montana Forensic Collection Case #141
… of ribs 8,9, and 10 are present. Degenerative joint disease is widespread throughout the skeleton, and cribra orbitalia is present. Time since death is difficult to estimate due to the manner of preparation of the skeleton.
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A Comprehensive Case Report of University of Montana Forensic Collection Case #141
… of ribs 8,9, and 10 are present. Degenerative joint disease is widespread throughout the skeleton, and cribra orbitalia is present. Time since death is difficult to estimate due to the manner of preparation of the skeleton.
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A Biphasic Multiscale Investigation of the Biomechanical Microenvironment of Articular Cartilage
Osteoarthritis (OA) is a debilitating joint disease that involves the degeneration of articular cartilage. Although much research has been conducted at the macroscale level, the microscale level is poorly understood. This thesis investigated the micromechanical environment of cartilage cells that …
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Peopling Portland’s Past: A paleodemographic, osteological and funerary investigation of the burial population excavated from the site of St. Andrew’s Church, Portland, UK.
… age-at- death categories, minimal trauma with joint disease the most common pathological condition in this burial population. No associations were made regarding age-at- death, biological sex, or pathological conditions in relation to spatial organization of burials at the site. Comparison to …
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Nutrient deficiencies in soils of the Mseleni area, Kwazulu-Natal
… been implicated in the etiology of an endemic disease. Mseleni Joint Disease (MJD) is a crippling, osteo-arthritic condition which afflicts an unusually high proportion of the inhabitants of this district. Home-grown produce and indigenous plants, which form the basis of the local diet, may be …
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The Pharmacist's Role in Consulting Patients with Joint Diseases // Роля на магистър-фармацевта при консултиране на болни със ставни заболявания
… condition of chronically ill patients with joint disease (osteoarthritis) through the application of individualized pharmaceutical care. Analyzing the available modern literature on the provision of pharmaceutical care, the features of pharmaceutical care in patients with chronic …
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The Influence of Frontal and Axial Plane Deformities on Contact Mechanics during Squatting: A Finite Element Study
Knee Osteoarthritis (KOA) is a degenerative joint disease and a leading cause of disability worldwide. Lower limb malalignment was a risky factor leading to KOA, altering the load distributions. This study aimed to study the influence of knee deformities on knee contact mechanics and knee …
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