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Showing 1 to 9 of 9 for “"jet injector"”.
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The dual-piston jet injector and the viability of drug delivery
Drug delivery through jet-injection opens the doors to very rapid drug dispersion by eliminating the need for needle sterilization. With this comes the need for a continuous flow of fluids from a large reservoir, currently not available to the single-piston drug delivery systems. A two-piston …
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Needle-free interstitial fluid acquisition using a Lorentz-force actuated jet injector
… ISF samples using a Lorentz-force actuated jet injector. The jet injector is used to first inject a small volume of physiological saline to breach the skin, and the actuator is subsequently back-driven to create a vacuum in the ampoule and collect a sample that contains a mixture of ISF and …
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Performance and design improvements toward the commercialization of a needle-free jet injector/
… Lab has developed a handheld needle-free jet injector based on a custom Lorentz-force motor. While the current handheld design is effective as a research tool, many improvements are needed before it can be a commercially viable product for individual human use. Improvements in various …
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Design and fabrication of a piezoelectric stack actuator for use in a needle-free jet injector
… ceramic stack actuator for use with needle-free jet injection (NFJI) devices. While NFJI devices have been in use for over 60 years only recently have they been electronically actuated which allows for precise control of jet velocity, penetration depth, and injection volume. Most NFJI devices …
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Lorentz-force actuated needle-free injection for intratympanic pharmaceutical delivery
… controlled linear Lorentz-force actuated jet injector developed in the MIT BioInstrumentation lab was found to be a feasible technology for possible improvement over current intratympanic drug delivery methods. Jet injection holes using a nozzle with a 50 [mu]m orifice were found to be …
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A contact force sensor for medical jet injection
Medical jet injection, in which a narrow fluid drug stream is propelled into the skin without a needle, was first conceived in the 1940s [1]. However, a major drawback of most injectors is the lack of controllability of jet parameters. Recent work at the BioInstrumentation Laboratory at MIT has …
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Evaluating delivery of a monoclonal antibody using a linear Lorentz-force actuated needle-free injector
… using a controllable auto-loading needle-free jet injector has been evaluated for two potentially limiting factors: viscosity of the formulation and shearing of the antibody during ejection. We used the Hepatitis B monoclonal antibody C86322M for its easy access and widespread usage. We used …
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Experimental Investigation and Modeling of Scale Effects in Micro Jet Pumps
… devices, beginning first with microscale jet engines and a generation later more broadly encompassing MEMS devices which generate power or pump heat. Due to small device scale and fabrication techniques, design constraints are highly coupled and conventional solutions for device …
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Innovative Transverse Jet Interaction Arrangements in Supersonic Crossflow
… on the premise that adding an array of auxiliary jets behind a main jet injector would alleviate the large region of low pressure typically found downstream of a normal, sonic injector in supersonic flow and also possibly increase in intensity of the upstream high-pressure region. The secondary …