Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 46 for “"isoflurane"”.
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Isoflurane : interaction with hepatic microsomal enzymes
… in rat hepatic microsomes. The interaction of isoflurane with cytochrome P-450 results in its metabolism to fluoride ion and organofluorine metabolites. The cytochrome P-450 isozymes catalysing the defluorination of isoflurane were assessed in hepatic microsomes from phenobarbital-, …
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Limiting Exposure to Isoflurane in a Veterinary Occupational Setting
<p>This paper characterizes the veterinary occupational health hazards of waste anesthesia gas. A needs assessment was conducted to develop educational materials on hazard and control. Rcommendations were made to HESIS on need for educational products.</p>
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In vitro Microdialysis Sampling Collection of Volatile Organic Compounds (VOC's), Dodecafluoropentane (DDFP) and Isoflurane
… can collect volatile organic compounds, isoflurane (a standard inhalation anesthetic) and DDFP. Different perfusion fluids and flow rates were tested for optimal analyte collection through the microdialysis membrane. Instead of utilizing an aqueous perfusion fluid safflower oil and air …
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Effect of Isoflurane Post-treatment on tPA-exaggerated Brain Injury in a Rat Ischemic Stroke Model
… aim of this study was to assess the effect of isoflurane post-treatment on intracranial hemorrhage and cerebral infarction after tPA treatment for transient cerebral ischemia. Cerebral ischemia was modeled in male Sprague-Dawley rats (n = 32) by occluding the right middle cerebral artery for 1 …
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Isoflurane-induced post-conditioning in senescent hearts is attenuated by failure to activate reperfusion injury salvage kinase pathway
… We investigated the cardioprotective effects of isoflurane administered at the onset of reperfusion in senescent rat in vivo, and the activation of the reperfusion injury salvage kinase (RISK) pathway to address a possible mechanism underlying age-related differences. METHODS AND RESULTS: Male …
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Effekte der Inhalationsanästhetika Isofluran und Xenon auf die systolische und diastolische Ventrikelfunktion während Myokardischämie
… studies investigated the effects of xenon and isoflurane on the systolic and diastolic function. Especially the informations on the impact of these anethestic agents on animals or humans with impaired left ventricular function are deficient. Both agents demonstrated cardioprotective properties …
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The Effect of General Anaesthesia on Circadian Rhythms in Mice
… halogenated inhalational anaesthetic agents (isoflurane and sevoflurane), administered at different times of the day (circadian times, CTs), over a period of 24 hours. To do so, I collected data to construct a full phase response curve (PRC) for each anaesthetic agent. Animals received either …
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Comparative effects of halothane, isoflurane, and enflurane on the hemodynamics of newborn and older pigs using ascorbic acid dilution to measure cardiac output
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Thrombelastographische Blutgerinnungsuntersuchungen gesunder Schweine unter Xenonmono- bzw. einer Kombinationsnarkose aus Xenon und den volatilen Inhalationsanästhetika Isofluran, Sevofluran, Halothan und Enfluran
… with other volatile anaesthetics, such as isoflurane, sevflurane, halothane or enflurane alter blood coagulation.Methods: The study was performed with 40 healthy pigs. They first underwent xenon monoanaesthesia (65 Vol%) and were then randomly assigned to combinations of xenon and …
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Veränderung der Hämodynamik durch die Kombinationsnarkose aus Xenon und Isofluran im Vergleich zu der aus Xenon und Sevofluran an Schweinen
… hemodynamic parameters in mono-anesthesia with isoflurane or sevoflurane were taken as baseline values. Therefore the volatile anesthetics were administered at 1.0, 1.3 and 1.6 MAC. After that measurements together with xenon and one of the volatiles were performed. Xenon was delivered at …
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Disbudding of dairy goat kids: Refining protocols to reduce or eliminate pain
… method evaluated in this thesis, the effect of isoflurane and meloxicam on pain associated with cautery disbudding was investigated. Goat kids disbudded under isoflurane, with or without meloxicam, had lower cortisol concentrations and displayed fewer head-directed behaviours than goat kids that …
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The influence of anesthesia and nicotine on dopamine signaling in the rat dorsal striatum
… signaling in the brain. Although urethane and isoflurane anesthetics are commonly used in in vivo studies, isoflurane’s potential influence on dopamine signaling has not been thoroughly investigated. In addition to this, the addictive nature of nicotine indicates the importance of understanding …
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Cardiovascular effects of a low and a high dose of fentanyl in the isoflurane anesthetized dog: the influence of the anesthetic-sparing effect and the correction of bradycardia
… function in dogs anesthetized with isoflurane. In previous literature, a high dose of fentanyl improved cardiovascular function in enflurane anesthetized dogs only following correction of bradycardia associated with its use. The objective of this study was to evaluate the effect of …
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Zur Frage der Stofftransporteigenschaften von Oxygenatorhohlfasermembranen bezüglich der Durchlässigkeit für Fluide und Narkosegase
… oxygenators for CPB, the halogenated anaesthetic isoflurane cannot be administered in sufficient amounts. In the set-up to test steam transfer, the PP and PMP oxygenator modules were analysed for differences in permeability through perfusion with distilled water on the fluid side and streaming of …
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Wirkung von milder Hypothermie auf den negativ inotropen Effekt von Halothan, Isofluran und Sevofluran auf ventrikuläres Kaninchen-Myokard
… response of the volatile anesthetics halothane, isoflurane and sevoflurane on ventricular rabbit myocardium. Measured parameters were contractility, the timing of contractions, response to the raise of extracellular calcium concentrations and the first contraction after a time interval without …
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Sound processing in the mouse auditory and dorsal neocortices
… simple and complex sounds presented to awake and isoflurane-anesthetized mice. For the feature detection theory, the auditory cortex (AC) maps of tone frequency and frequency modulation (FM) rate are updated. In these maps, new areas and topographic gradients are discovered. The maps are stable …
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Hemodynamic Changes after Endotracheal Iintubation with a Lightwand or a Laryngoscope in Patients with Cerebral Aneurysm
… mg/kg). The lungs were ventilated with 3% isoflurane in oxygen. 1% lidocaine(1 mg/kg) were administered 90 seconds before the intubation. Patients were then intubated with either the lightwand or the laryngoscope when end expiratory isoflurane concentration 2 vol% and BIS less than 40. Room …
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Shedding Light On General Anesthesia: Uncovering The Molecular Mechanisms For Propofol And Volatile Anesthetics
… volatile anesthetics sevoflurane and isoflurane, as well as the most commonly used intravenous anesthetic, propofol. A novel photoaffinity ligand for sevoflurane was validated and applied to uncover the unique mechanism of sevoflurane positive modulation of mammalian Shaker Kv1.2 …
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