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Showing 1 to 20 of 59 for “"isoflavones"”.
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Soy isoflavones and swine health
… Among potential components, soy-derived isoflavones show promise as a nutritional intervention against a pathogenic challenge due to their antiviral and anti-inflammatory properties. For swine in particular, there are a number of pathogenic challenges a pig may face throughout its …
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The HIV-1 entry inhibition capabilities of Isoflavones
… investigated the anti-HIV activity of five novel Isoflavones. Isoflavones and similar compounds have been extensively researched for their ability to hinder HIV reproduction through multiple routes of antagonism in the HIV life cycle but with little research in HIV entry inhibition. In this study, …
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Design and synthesis of novel biologically active flavones and isoflavones
The primary aim of this project was to develop different methodologies for the synthesis of novel 4-arylisoflavans and isoflavenes or analogues that structurally resemble isoflavonoids. In addition, the incorporation of fused-ring systems into the isoflavonoid scaffold to synthesize analogues of a …
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Mechanisms of soy isoflavones in the regulation of vascular function
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the United States. It is also well recognized that the incidence of CVD is substantially increased in postmenopausal women due to the loss of estrogen. Experimental and clinical data support vascular protective …
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Effect of Soy Protein, Isoflavones and Methionine Supplementation on Lipid Metabolism
… analyzed the interaction of soy protein, dietary isoflavones and methionine supplementation as possible hypocholesterolemic agents. Results from our time course experiment indicated that gerbils fed casein had higher serum total cholesterol concentrations compared to gerbils fed alcohol-washed, …
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In Vitro and in Vivo Modulation of Rotavirus Infection by Soy Isoflavones
… containing naturally high concentration of isoflavones, which possess anti-viral and antiinflammatory properties. Thus, the objective of this research was to investigate the potential effectiveness and underlying mechanisms whereby dietary isoflavones, at concentrations present in soy-based …
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THE EFFECTS OF PUBERTAL EXPOSURE TO DIETARY SOY ISOFLAVONES ON THE BREAST AND REPRODUCTIVE TISSUES
… which contains the phytoestrogenic compounds isoflavones (IFs), is associated with reduced breast cancer risk. A similar relationship has been reported for soy and endometrial cancer, although the evidence is more limited. Interestingly, the inverse association between soy and breast cancer is …
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Enhancing the transformation level of bioactive soy isoflavones in soy-based foods by probiotic organisms
The biologically active forms of the isoflavones, aglycones (IA), in soy are reported to have many health benefits and could be considered as a “natural component” to replenish the estrogens in woman at menopausal and post-menopausal age. However, the isoflavones in soy exist principally in …
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Soy Isoflavones Mediate Radioprotection Of Normal Lung Tissue By Modulating The Radiation-Induced Inflammatory Response
… that supplementation with a mixture soy isoflavones (genistein, daidzein, and glycitein) has the dual capability of protecting normal lung tissue from radiation injury while simultaneously enhancing radiation damage in the tumor. However, mechanisms of radioprotection by soy isoflavones …
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Bifidobacterial enzymic transformation of isoflavones, their bioavailability and effects on disease risk biomarkers in postmenopausal women
Soybeans and non-fermented soyfoods, including soymilk, contain only 5 to 10% of total isoflavone in a biologically active aglycone configuration, with the remainder found as isoflavone glucoside conjugates. Saccharolytic enzyme-producing Bifidobacterium, classified as probiotics, are commonly …
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Isotopic labeling of isoflavones from plant cell and organ culture for metabolic tracking in animal models
Kudzu and red clover isoflavones are phytoestrogens that have been investigated as alternatives to estrogen replacement for treatment of osteoporosis, cardiovascular disease, and neurological disorders. However, the pharmacokinetics of these compounds are not clearly understood. In the present …
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Enhanced β-galctosidase activity in probiotics for improved bioconversion of soy isoflavones in dairy and soy-based yoghurt
The main aims of this project were to evaluate the suitability of whey as a medium for the production of β- galactosidase (β-gal) from Lactobacillus delbrueckii ssp. bulgaricus ATCC 11842 (LB) and Bifidobacterium animalis Bb12 (BB12). The study was undertaken to examine and compare the influence of …
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Characterisation of oestrogenic properties of Isoflavones derived from Millettia griffoniana Baill.: - Molecular mode of action and tissue selectivity
Six isoflavones derived from Millettia griffoniana namely, 4’-methoxy-7-O-[(E)-3-methyl-7hydroxymethyl-2,6 octadienyl]isoflavone (7-O-DHF), Griffonianone C (Griff C), 7-O-geranylformononetin (7-O-GF), 3’,4’-dihydroxy-7-O-[(E)-3,7-dimethyl-2,6-octadienyl]isoflavone (7-O-GISO), Griffonianone E (Griff …
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Stability of bioactive isoflavones and glycolytic enzymes produced by probiotic bacteria in soy based food during processing and storage
… to the biologically active aglycones in soymilk. Isoflavones quantification with HPLC and β-glucosidase activity was performed after 0, 12, 24, 36, and 48 h of incubation in soymilk at 37°C. All 6 microorganisms produced β-glucosidase, which hydrolysed the predominant isoflavone β-glycosides. …
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Nuevos métodos para la determinación de isoflavonas en soja y alimentos derivados
In this Doctoral Thesis several aspects of soy isoflavones determination were assessed for the development of new methods for the extraction, clean-up/concentration and hydrolysis, as well as new analysis methods by high performance chromatography methods. Previously, the stability of soy …
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Development of a standardized functional soy product for cancer prevention trials:Phase II evaluation of isoflavone bioavailability in men with asymptomatic prostate cancer
<p>Soy isoflavones have generated substantial interest in the last few decades. However, bioavailability, metabolism, bioactivity and structural fate of isoflavones have been the subject of much stimulating discussion. Of the many dietary variables of interest, diets rich in soy foods are …
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The Effects of Soy Protein and Isoflavones on Lipid Oxidation and Blood Lipid Profile on Humans Participating in Moderate Physical Activity
The purpose of our study was to compare the effects of dietary soy protein and animal protein (casein) on plasma lipoprotein concentrations, and exercise induced oxidation in human subjects. Sixteen normocholesterolemic young men participated in 30 min of cycling at 70% VO2pk to induce plasma …
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The effect of soy isoflavone intake on cardiovascular disease risk factors - potential role of equol
Isoflavones, the subclass of flavonoids found in soybeans, may reduce the risk of cardiovascular disease (CVD). However, the current evidence is inconsistent. The capability to produce the isoflavone metabolite equol in 20-60 % of the population might underlie the benefits of isoflavone intake on …
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The Effects of Isoflavone Supplementation on Rats and Humans
Isoflavones have antioxidant activities in vivo, however, their antioxidative potential against oxidative stress initiated by exercise was not explored. The first study investigated the effect of high-genistin isoflavone (HGI) supplementation on erythrocyte antioxidant enzymes and tissues' …
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Soy Isoflavone Supplementation Does Not Alter Lymphocyte Proliferation and Cytokine Production In Postmenopausal Women
… in vitro and animal studies suggest that soy isoflavones may either enhance or suppress immunocompetence, depending upon the isoflavone concentration, target tissue, and a number of other factors. To date, no study has investigated the effect of dietary soy isoflavone supplementation on immune …
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