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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 42 for “"isoenzyme"”.
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Electrochemical dynamics of cytochrome P450-3A4 isoenzyme biosensor for protease inhibitor antiretroviral drug
… recombinant heme thiolate, cytochrome P450 3A4 isoenzyme (CYP3A4), as biorecognition component. Secondly, each biosensor platform was evaluated by using an entirely different category of compound as model substrate, with the overall objective being the development of alternative analytical …
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The identification, purification and characterization of the fetal rat liver glutathione S-transferase isoenzyme YcYfetus
… of the GSH S-T in fetal livers. The novel fetal isoenzyme comprising this subunit was purified using a combination of affinity chromatography, carboxymethyl-cellulose column chromatography and chromatofocusing. The six major basic rat liver GSH S-T were purified for reference and comparative …
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Effect of Photoperiod on Developmental Morphology and Enolase Isoenzyme Immunohistochemistry in Rat and Djungarian Hamster Superficial Pineal Glands
… tissues. Homodimer non-neuronal enolase isoenzyme (NNE) is immunolocalized to cells, and the hybrid enolase (consisting of subunits from NSE and NNE) has been seen in cerebellar stellate and basket cells. Although not rate limiting, concentrations of both NSE and NNE in the rat pineal …
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The glutathione S-transferases : kinetics, binding and inhibition
… of xenobiotics. The cytosolic GSH S-transferase isoenzymes of rat, man and mouse have been assigned to three groups, Alpha, Mu and Pi, based on N-terrninal amino acid sequences, substrate specificities, immunological cross-reactivity and sensitivities to inhibitors. The kinetic mechanism of the …
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Corticosteroid Induced Alkaline Phosphatase: Cellular Location, Biochemical Characterization and Comparison to Intestinal Alkaline Phosphatase of the Dog (Amino Acid, Monoclonal Antibody, Peptide Mapping, Carbohydrate, N-Terminal)
… location of the corticosteroid-induced isoenzyme of alkaline phosphatase (SIALP) in the liver, purify the SIALP, the intestinal isoenzyme of alkaline phosphatase (IALP) and the hepatic isoenzyme of alkaline phosphatase (LALP), develop an effective means of purification for IALP and …
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ΚΙΝΑΣΗ ΤΗΣ ΦΩΣΦΟΡΥΛΑΣΗΣ ΑΠΟ ΛΕΙΟ ΜΥΙΚΟ ΙΣΤΟ ΣΤΟΜΑΧΙΟΥ ΚΟΤΑΣ: ΑΠΟΜΟΝΩΣΗ ΚΑΙ ΜΕΛΕΤΗ ΤΩΝ ΚΑΤΑΛΥΤΙΚΩΝ ΚΑΙ ΔΟΜΙΚΩΝ ΙΔΙΟΤΗΤΩΝ ΤΗΣ
… TO THOSE FOUND FOR THE RABBIT SKELETAL MUSCLE ISOENZYME. ALTHOUGH BOTH KINASES HAVE THE SAME HIGH MOLECULAR WEIGHT (1.3 X 106), THE SUBUNIT STRUCTURE OF THESE ISOENZYMES ARE DIFFERENT. ELECTROPHORETIC DATA INDICATES THAT CHICHEN GIZZARD PHOSPHORYLASE KINASE DOES NOT COMPRISE Γ SUBUNIT IN ITS …
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Characterization of Pea Seed Lipoxygenase Isoenzymes
… characterize an alkaline pH optimum lipoxygenase isoenzyme from pea seeds, and to more extensively characterize two neutral pH optimum pea seed lipoxygenases. The isoenzymes were purified to homogeneity by using a combination of ammonium sulf
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Distinct roles of PI4P 5-kinase isoforms in polar tip growth of pollen tubes
… Auf Grund ihrer Domänenstruktur können die Isoenzyme in zwei Unterfamilien A und B unterteilt werden. Die Analyse von Arabidopsis Mutanten, die in der Expression verschiedener PI4P 5-Kinasen gestört sind, zeigte, dass Typ A Isoenzyme essentiell für die Pollenentwicklung sind, während Typ B …
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Inhibition of horseradish peroxidase activity by specific antibody
… may make the horseradish peroxidase basic isoenzyme more susceptible to peroxide inactivation. Kinetic data show increased enzyme affinity for hydrogen peroxide in the presence of antibody. In addition, acidic peroxidases that are less susceptible to peroxide are poorly inhibited by …
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Kompartementalisierung des Kohlenhydrat-Stoffwechsels in Toxoplasma gondii
… wobei insbesondere die Zuordnung einzelner Isoenzyme zu Apicoplast, Mitochondrium und Zytosol im Vordergrund standen. Die Lokalisationen der in dieser Arbeit identifizierten Isoenzyme der Glykolyse, eines vollständigen Zitronensäure-Zyklus sowie weiterer, diesen Stoffwechselwegen …
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ΜΕΤΑΒΟΛΕΣ ΤΗΣ ΟΛΙΚΗΣ ΚΡΕΑΤΙΝΟΦΩΣΦΟΚΙΝΑΣΗΣ ΟΡΟΥ ΚΑΙ ΤΩΝ ΙΣΟΕΝΖΥΜΩΝ ΤΗΣ ΥΠΟ ΤΗΝ ΕΠΙΔΡΑΣΗ ΑΝΑΙΣΘΗΣΙΟΛΟΓΙΚΩΝ ΠΑΡΑΓΟΝΤΩΝ ΚΑΤΑ ΤΗ ΔΙΑΡΚΕΙΑ ΤΟΥ ΦΥΣΙΟΛΟΓΙΚΟΥ ΤΟΚΕΤΟΥ ΚΑΙ ΤΟΥ ΤΟΚΕΤΟΥ ΜΕ ΚΑΙΣΑΡΙΚΗ ΤΟΜΗ
… ATLAST IT SEEMED FROM THE STUDY OF CPK ISOENZYMES THAT THE ISOENZYME WHICH WAS PREDOMINANT IN BOTH GROUPS OF WOMEN WAS THE SKELETAL MUSCLE TYPE (MM) OF 93-100%. WE PROPOSE THE MEASUREMENT OF TOTAL CPK AND ITS ISOENZYMES AS A ROUTINE METHOD FOR ALL PREGNANT WOMEN, WHO ARE GOING TO RECEIVE …
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Regulation and function of extracellular invertases of tomato
… sich in dem Auftreten verschiedener Invertase- Isoenzyme mit speziellen Expressions- und Regulationsmustern wider, welche eine Koordination des Kohlenhydratmetabolismus in unterschiedlichen Geweben, zu unterschiedlichen Entwicklungsstufen und unter sich ändernden Umweltbedingungen ermöglichen. …
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Clinical and pathophysiologic studies of increased alkaline phosphatase isoenzymes in the liver and serum of dogs
… necessary for liver alkaline phosphatase isoenzymes to increase in canine blood were examined. It was first shown by a clinical study that increased serum activity of the corticosteroid-induced isoenzyme of alkaline phosphatase (CALP), which is unique to dogs, occurs in many different …
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Evaluation of the induction of rat hepatic and pancreatic glutathione S-transferases by treatment with the cruciferous nitrile, cyanohydroxybutene
… including the glutathione S-transferase isoenzymes (GSTs). The GSTs catalyze the conjugation of glutathione (GSH) to electrophilic xenobiotics. As peroxidases, they detoxify organic hydroperoxides. Each isoenzyme has a unique level of activity in detoxifying xenobiotics, including certain …
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Design, synthesis, and biological evaluation of selective sphingosine kinase inhibitors
… different roles inside the cell. The dearth of isoenzyme-selective inhibitors has been a stumbling block for probing the exact roles of these two isoforms in disease progression. This report documents our efforts in developing SphK2-selective inhibitors. We provide the first demonstration of a …
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Untersuchungen zu Auswirkungen von GAG-Linkeropathien auf die ECM-Homöstase durch die Generierung von knockout-Modellen in Dermalfibroblasten
… XT-II) auf. Zur Analyse der Relevanz der beiden Isoenzyme wurde in dieser Arbeit erstmals ein massenspektrometrischer Assay zur simultanen und selektiven Quantifizierung der XT-I- und XT-II-Aktivität entwickelt. Mittels eines postulierten mathematischen Modells kann die jeweilige Aktivität der …
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Characteristics and applications of the enhanced HRP-catalyzed oxidation of luminol
… concentration, pH, CL molecule, oxidants, HRP isoenzyme composition and the CL emission spectrum. This research project studied the p-iodophenol enhanced HRP-catalyzed oxidation of luminol improve the understanding of this reaction. The rate and total yield of photon emission, the rate and …
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