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Showing 1 to 1 of 1 for “"isoDGR"”.
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Evaluation of new succinimide-based small molecules as alphavbeta3 integrin antagonists: from design to preliminary biological testing
… limit may be overpassed by switching from RGD to isoDGR motif. Here, some isoDGR analogues prodrugs have been designed and synthesised, by a multi-step route to obtain the different fragments (isoAsp, Gly and Arg) subsequently connected together [Fig. A.01]. The molecules have been tested in …