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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 140 for “"ischemic stroke"”.
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Vascular receptor changes in ischemic stroke
The present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. In addition, rat cerebral arteries and arterial smooth muscle …
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Aging Exacerbates Neutrophil Pathogenicity In Ischemic Stroke
<p>Ischemic stroke is a major cause of disability and mortality worldwide. As most patients cannot receive the currently approved therapies for ischemic stroke, novel treatments are critically needed. Cerebral ischemia causes irreversible tissue damage, referred to as the “tissue core”, which is …
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Radiation induced vascular disease and ischemic stroke.
Contains fulltext : 74396.pdf (Publisher’s version ) (Open Access)
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fMRI assessment of ischemic stroke in humans
Cerebral ischemia, or brain ischemia is a kind of stroke where the blood flow is insufficient to the metabolic demand of brain. The lack of oxygen supply will directly lead to the death of brain tissue. There are two major injury regions: the infarct and penumbra. Mostly, since the infarct regions …
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The Role of Wnt3a in Ischemic Stroke
<p>After ischemic stroke, apoptosis of neurons is a primary factor in determining outcome. Wnt3a is a naturally occurring protein that has been shown to have protective effects in the brain for traumatic brain injury. Although wnt3a has been investigated in the phenomena of neurogenesis, …
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Clinical Prediction of Perinatal Arterial Ischemic Stroke
Perinatal stroke is a well-defined but heterogenous group of disorders involving a focal disruption of cerebral blood flow between 20 weeks gestation and 28 days of life. At a combined incidence of 1:1000 live births, stroke in the perinatal period is more common than at any other time in …
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Therapeutic Targeting of Arteriogenesis Following Ischemic Stroke
Strokes are a leading cause of death and disability in the United States, predominantly caused by ischemic events. Ischemic strokes occur when a clot or other obstruction lodges in a blood vessel of the brain, restricting the movement of blood. Subsequent rapid cell death occurs and often leads to …
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Early Identification of Dysphagia Post Pediatric Ischemic Stroke
Pediatric stroke has received increasing attention over the last few decades. Dysphagia is commonly reported following acute stroke in adults, leading to negative health complications such as pneumonia and mortality; however, dysphagia is not a well understood outcome post-stroke in pediatrics. …
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Mean Arterial Pressure in Acute Ischemic Stroke Study
… in the acute care setting. Despite this, acute stroke practitioners trust and rely on non-invasive blood pressure (NIBP) devices to guide acute ischemic stroke (AIS) patients’ treatment. Although systolic blood pressure (SBP) has been found to be the most unreliable measurement displayed on NIBP …
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Neuropsychological Effects of Pomegranate Supplementation Following Ischemic Stroke
… particularly high polyphenol content. Since stroke induces both oxidative stress and inflammation and is currently the leading cause of long-term disability in the U.S., we sought to determine whether dietary supplementation with polyphenols could enhance cognitive recovery in individuals who …
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INVESTIGATION OF GENETIC FACTORS DETERMINING ISCHEMIC STROKE OUTCOME
<p>Cerebrovascular disease (stroke), especially ischemic stroke, is a major cause of death and neurological disability in adults. Because of its clinical heterogeneity, stroke is considered as a multi-factorial and polygenic disorder. Most current genetic studies of ischemic stroke focus on genetic …
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The Advantage of the Thromboaspiration in Acute Ischemic Stroke
급성 뇌졸중은 우리나라에서 사망원인 중 하나로 시간이 환자에게 발생하는 합병증을 줄일 수 있는 가장 중요한 중요인자이다. 우리는 뇌졸중 센터 개소 이후 2년 동안 경험했던 자료를 바탕으로 폐색된 혈관을 재개통하는 가장 좋은 방법이 무엇인지에 대해 찾으려 했다. 2008년 3월 1일부터 2010년 2월 28일까지 후향적 조사를 실시하였고 급성 허혈성 뇌졸중 환자에 대해 치료 및 결과에 대해 분석하였다. 기계적 혈전용해술 방법들 중에서 혈전흡입술을 첫 번째 방법으로 선택하여 치료하였을 때 NIHSS, mRS, 재개통율, 시술 후 …
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The Use of Ischemia-modified Albumin(IMA) in Ischemic Stroke
… (IMA) as a new and rapid diagnostic biomarker of ischemic stroke and compare IMA in progression of stroke and non-progression of ischemic stroke. METHODS: Fifty-two emergency patients with acute neurologic symptoms were admitted to the emergency department within 6 hours of symptom onset (28 …
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ACUTE ISCHEMIC STROKE: CANCER-RELATED STROKE AND MULTIMODAL ANALYSIS OF THROMBI.
Background Acute ischemic stroke (AIS) usually results from atherosclerosis or cardiac sources, but less frequent mechanisms, such as cancer-related stroke, play a role in some cases. Studying these rarer causes of AIS is crucial for secondary prevention. Thrombi analysis provides a unique window …
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Expansion of neural stem cells as a treatment for ischemic stroke
Adulte Neurogenese in Säugetieren ist eingeschränkt auf zwei Gehirnbereiche, der subgranulären Zone (SGZ) des Hippocampus und der subventrikulären Zone (SVZ) um die Ventrikelwände herum. Vorhergehende Arbeiten in unserem Labor haben gezeigt, dass Überexpression der Zellzyklusregulatoren Cdk4/Ccnd1 …
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Gene Delivery to the Blood-Brain Barrier for Ischemic Stroke Therapy
<p>Stroke is a major cause of death in the United States. We aim to develop safe and efficient approaches for the treatment of stroke. Regenerative therapies have been identified as the major need for curing stroke [1]. We explored two different carriers (poly (ethylene glycol)<sub>5k</sub>-poly …
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A Paper-Based Elisa Device for the Rapid Detection of Ischemic Stroke
<p>Diagnosing an ischemic stroke quickly and accurately is essential for appropriate treatment and results in more effective management of the stroke, leading to better patient outcomes. Specifically, the determination of ischemic versus hemorrhagic stroke leads to critically different treatment …
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Machine learning models for functional impairment risk prediction in ischemic stroke patients
Background: Stroke-related functional impairment risk scores are commonly used to estimate the patient-specific risk of functional impairment in acute care settings. However, these models have been primarily developed based on regression models, which might not provide optimal predictive accuracy, …
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Gelatin nanoparticles for improved neuroprotection of intranasally delivered osteopontin in ischemic stroke
… delivery of a peptide fragment to treat ischemic stroke in a rat model as proof-of-concept. Ischemic stroke is a leading cause of adult disability and 4th leading cause of death worldwide. The major impediments to functional recovery following stroke are short therapeutic windows and a …
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Unraveling the Role of EphA4 in Immune-Mediated Arteriogenesis After Ischemic Stroke
Stroke, a life-threatening condition, primarily resulting from ischemic events often caused by occlusion of the middle cerebral artery (MCA). Pre-existing leptomeningeal collateral (LMC) vessels connect MCA branches to anterior or posterior arteries, situated along the brain's cortical surface or …
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