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Showing 1 to 14 of 14 for “"ischemic preconditioning"”.
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Effects of Ischemic Preconditioning on Exercise Economy
<p>Ischemic preconditioning (IPC) is the application of small bouts of ischemia followed by reperfusion. IPC has shown to enhance exercise performance in varied sports like 5K running, cycling and swimming. However, effect of ischemic preconditioning on running economy have not be investigated so …
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Influence of Cardiovascular Risk factors on Remote Ischemic Preconditioning
… ischemia-reperfusion injury is remote ischemic preconditioning (rIPC), which triggers tissue protection by exposing a limb to small cycles of vascular occlusion. Animal models indicate that CVD risk factors reduce the protective benefits of ischemic conditioning. However, there are no …
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The Effect of Ischemic Preconditioning on Rock Climbing Performance
… blood flow and causing ischemia-induced fatigue. Ischemic preconditioning (IPC) has been shown to improve time to failure (TTF) during climbing-specific tasks, though its mechanisms remain unclear. The purpose of this study was to assess the effects of IPC on hemodynamics and muscle oxygenation …
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Ischemic Preconditioning and Hydrodynamic Delivery for the Prevention of Acute Kidney Injury
… whose primary treatment is supportive care. Ischemic preconditioning is a strategy used to protect organs from ischemic injury via a prior injury. Ischemic preconditioning in the kidneys has been shown to confer protection onto kidneys from subsequent ischemic insults with attenuated serum …
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Investigating the Ergogenic Potential of Ischemic Preconditioning and Resisted Running on Sprint Performance
… against a load equal to ~ 40 % body mass) or ischemic preconditioning protocol (3 x 5 min occlusion) acutely affected sprint performance. These findings indicate that the intensity of the resisted sprint protocol and manner in which the ischemic pre-conditioning protocol was performed provided …
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The Effects of Prolonged Bouts of Exercise and Acute Ischemic Preconditioning on Cardiac Biomarker Release
… was studied indirectly by employing remote ischemic preconditioning (RIPC) in a single-blind cross-over research design. In study 3 trained cyclists completed 2 one hour time trials in a controlled laboratory environment with trials preceded immediately RIPC or a SHAM protocol. Hs-cTnI …
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Ischemic Preconditioning Protects Adult Rat Cardiomyocytes Against Necrosis but not Apoptosis, via Activation of PKG
… is well established; however its role in the ischemic preconditioning (IPC) of cardiomyocytes is not clearly defined. In the current study, we assessed the hypothesis that PKG protects against cell death following ischemidreperfusion injury in myocytes subjected to IPC. Freshly isolated adult …
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Can exercise mediate similar beneficial effects on endothelial function and endothelial reperfusion injury as ischemic preconditioning?
… immediate cardioprotection, similar to that of ischemic preconditioning (IPC). Whilst there is evidence that IPC (short repeated bouts of non-lethal ischemia followed by reperfusion) offers a biphasic pattern of protection and has both local (at site of injury) and remote effects (site distant …
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The role of signal transducer and activator of transcription-3 (STAT-3) in ischaemic and pharmacological preconditioning
Ischemic preconditioning is a protective mechanism whereby repetitive transient ischaemia confer protection against the subsequent prolonged lethal ischaemia that is observed during myocardial infarction. This protective phenomenon that lessens myocardial infarction can be mimicked by the cytokine …
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Precondizionamento ischemico non migliora la prestazione in atleti mezzofondisti in una prova sui 5000 metri di “self paced exercise”
The ischemic preconditioning (IP) is a protective phenomenon against cell injury induced by infarction. Furthermore, muscle IP has been found capable of improving exercise performance in laboratory testing. This investigation aimed at verifying the hypothesis that IP improved performance during …
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Signalling pathways involved in TNFα-induced cytoprotection : role of reactive oxygen species
… been shown in our laboratory that TNFa can mimic ischemic preconditioning (IPC). However, the signalling pathways involved in this protection remain incompletely understood. One potential protective pathway involves the generation of reactive oxygen species (ROS), which are known to be activated …
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EXERCISE-INDUCED ORGAN PROTECTION IN A MURINE MODEL OF CARDIAC ARREST AND RESUSCITATION
Cardiac arrest causes whole-body ischemic injury and cell death. Successful cardiopulmonary resuscitation paradoxically confounds recovery by increasing the rate of cellular death and tissue damage through global reperfusion injury. Despite decades of basic and clinical research, the prognosis …
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Epigenetic influence on cardiovascular protective mechanisms in vivo: explorations of t-PA release and extracellular vesicle genetic content
ABSTRACT Background: Ischemic heart disease is one of the leading causes of death globally. This thesis explores endogenous mechanisms protecting against myocardial ischemia in context of epigenetics (changes in gene activity not caused by changes in DNA sequences). Epigenetic regulation of …