Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"iron mobilization"”.
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Minimizing higher-order aggregation maximizes iron mobilization by small molecules
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-08-01
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From yeast to animals: A small molecule restores iron mobilization, absorption and hemoglobinization
… this strategy is no longer viable. Disorders of iron metabolism are the most prevalent genetic diseases worldwide and currently, there are more than 25 different human hereditary diseases associated with loss of iron transporter function and therefore aberrant iron transport, homeostasis and/or …
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From physiology to pixels: Resource allocation tradeoffs and noninvasive technologies for studying marine mammals
… balance and metabolism, stress physiology, and iron mobilization relate to reproductive history to reveal mechanisms governing maternal trade-offs between self-maintenance and reproduction. High-quality females that had consistently higher reproductive output, exhibited elevated ‘stress hormone’ …
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Hinokitiol restores hemoglobinization and mitigates neurodegeneration in animals by re-establishing iron homeostasis
Iron misdistribution disorder is characterized by iron accumulation and iron deficiency in various sites due to ferroportin (FPN1) dysfunction. Genetic FPN1 deficiency causes Ferroportin disease (FD), which is characterized by iron deposition in liver macrophages and anemia. Aside from …
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Restored iron transport by a small molecule promotes absorption and hemoglobinization: discovery, development, and mechanistic studies
… physiology to the protein deficient organism. Iron is a critical cofactor in all forms of life, yet its excess is paradoxically toxic. Organisms have thus developed sophisticated homeostatic networks of iron-transport proteins and their regulators to maintain iron at levels sufficient for …