Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"iron biomarkers"”.
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Genetic and environmental modifiers of iron overload disease. Why do only some patients get serious health outcomes?
Type 1 genetic haemochromatosis causes iron overload and is most commonly caused by homozygosity for the HFE C282Y variant and to a far lesser extent other HFE C282Y and H63D genotypes. Haemochromatosis is one of the most common genetic conditions in populations of Northern European ancestry, with …
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Effects of blood donation and iron homeostasis on medium and long term cardiometabolic outcomes
… of research, the relevance of blood donation and iron homeostasis on cardiometabolic outcomes remains unclear. Objectives. This thesis aims to reliably characterise the relevance of blood donation and iron homeostasis on cardiometabolic outcomes while overcoming some limitations of previous …
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Investigation into the causal effect of iron metabolism on cardiovascular disease
Background: The iron-heart hypothesis, put forward in 1981, proposes that higher iron levels are responsible for an increased risk of cardiovascular disease in men and post-menopausal women compared to pre-menopausal women. However, despite 30 years of research into this suggested association, …