Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 260 for “"ionizing radiation"”.
-
Ionizing radiation effects spectroscopy
… systems. Various stresses, such as exposure to ionizing radiation and extreme temperatures can result in performance degradation, transient anomalies, and hard failures. These issues have become evident in recent years with the increasing interest in the use of commercial-off-the-shelf (COTS) …
-
Epigenetic Response to Low-Dose Ionizing Radiation
<p>Low-dose ionizing radiation (LDIR) exposure (under 10.0 centigray (cGy)) from man-made sources, such as diagnostic imaging, predominates in the US population and comprises nearly 50% of an average individual's yearly radiation exposure (Ullrich, Brooks et al. 2009). The increase in such …
-
Late Effects of Ionizing Radiation on Normal Microvascular Networks
<p>Therapeutic doses of ionizing radiation result in changes in the structure and function of microvascular networks in normal tissue. Previously, we reported on the early effects of ionizing radiation on microvascular networks at 3, 7, and 30 days post-irradiation [1-3]. Data from the early time …
-
Ionizing Radiation and Endostatin Gene Therapy Against Lung Tumor
… continue to always be important issues for radiation oncologists. Numerous reports have also documented that radiation exposure increases the risk for malignancy and suppresses immune mechanisms. However, increasing evidence has suggested that anti-angiogenic therapy that targets tumor blood …
-
The role of c-FLIP in regulating resistance to ionizing radiation
… the efficiency of cell death induction by ionizing radiation (IR) are required to improve therapeutic outcomes. FLIP, anendogenous caspase-8 inhibitor is a critical regulator of cell death that is frequently overexpressed in various cancers. FLIP overexpression in cancer contributes to …
-
Effects of ionizing radiation on normal and tumor-associated lymphatic vessels
… cancer cells to lymph nodes. The effects of radiation on these vessels, however, are largely unknown. Here, we seek to describe the effects of ionizing radiation on normal and tumor-associated lymphatic vessels in vitro and in vivo. Clonogenic assays were employed to study the radiation dose …
-
New approaches in training for in situ visualization of ionizing radiation measurements
Surveying an environment for sources of ionizing radiation requires the use of measurement tools and skills developed from training in order to understand and analyze measurements. Recent advances in technology allow for new approaches to be made in the radiation survey methodology generally used …
-
Studying Mechanisms of Ionizing Radiation Resistance in Bacteria: Evidence for Multiple Pathways
Our lab created ionizing radiation (IR) resistant populations of E. coli MG1655 through twenty cycles of exposure to IR and outgrowth. To identify the genetic alterations responsible for increased IR tolerance, a total of seven isolates from the evolved final population were re-sequenced. However, …
-
Increased biopolymer pigment production in bacteria and fungi exposed to ionizing radiation
A major concern for manned space missions is ionizing radiation, which is known to pose both acute and chronic risks to many organisms. It is critical to expand strategies for radiation protection, including utilizing new materials and fabrication methods designed to support and augment health and …
-
Point-based Ionizing Radiation Dosimetry Using Radiochromic Materials and a Fibreoptic Readout System
… applicability in real-time in vivo dosimetry of ionizing radiation. Both films were able to produce a real-time measurement of optical density from a small volume, allowing positioning onto a tip of an optical fibre in the future. The increase in optical density was linear with absorbed dose for …
-
An Analysis of the Influence of Age and Ionizing Radiation on Cognitive Performance
… cognitive test results among persons exposed to ionizing radiation. The data for this investigation came from the fourth year of a 1995-98 longitudinal study of subjects exposed to radiation from the 1986 Chernobyl, Ukraine, nuclear power plant accident. Accuracy and efficiency scores from four …
-
Cytogenetic Analysis Of Depleted Uranium Exposure And Age-Dependent Susceptibility To Ionizing Radiation
… age influences individual susceptibility to ionizing radiation, blood samples were collected from 20 adults and from the umbilical cords of 10 newborns. Samples were acutely exposed to Cobalt 60 gamma rays to doses of 0 (control), 1, 2, 3 and 4 Gy. Cells in metaphase were labeled with whole …
-
Understanding The Repair Mechanisms at Ionizing Radiation-induced Damage in The Human Genome
Ionizing radiation (IR) such as X-rays induce damage clusters in the genome that include DNA double-strand breaks (DSB) with unligatable dirty ends, along with more frequent oxidized bases and single-strand breaks (SSB). While nonhomologous end joining and homologous recombination are major DSB …
-
Protein Biomarkers of Ionizing Radiation and Standardization by MALDI MS/MS and Quantification
… down-regulated following exposure to whole-body ionizing radiation (IR). The objective is to use these proteins as potential biomarkers of exposure to ionizing radiation of 2 Gy or greater which is the tolerance level for radiation sickness. Once these protein biomarkers are obtained, their …
-
A Preclinical Model of Ionizing Radiation and TNF-alpha Gene Therapy for Cancer
… Factor-α (TNF-α) could enhance the effect of ionizing radiation in an aggressive, rapidly growing glioma tumor (C6) model. Plasmid DNA is an attractive vector system for delivery of foreign genes into eukaryotic cells due to its advantages including low immunogenicity <em>in vivo</em>, lesser …
-
Development of New Radiolabeling Methods and Insights on Ionizing Radiation Interactions with Nanoparticles
… describes mechanisms of interaction between ionizing radiation and nanoparticles.</p> <p>The following advancements will be presented in this dissertation: i) a new radiolabeling method for silica and silica-based nanoparticles that does not require the use of specific chelators, with both …
Page 1 of 13