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Showing 1 to 20 of 21 for “"inverted repeats"”.
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Naujų Mu transpozonų konstravimas ir jų panaudojimas baltymų struktūros tyrimuose /
… endonucleases MreI, Bsp1407I, BseXI, AarI within inverted repeats. The efficiency of transposition of modified transposons was established. The results have shown that transposons with identical inverted repeats (MreI, Bsp1407I or BseXI) are as effective as their progenitor Tn-Km. However, mosaic …
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An investigation of the replication of the broad-host-range plasmid pTF-FC2
… (bp) DNA sequences and two sets of complementary inverted repeats. The 22 bp direct repeats appeared to be essential for replication and also for incompatibility. The role of one of the two sets of complementary inverted repeats was unclear. The deletion plasmid previously shown to replicate at …
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Sequence and Functional Structures of the Extrachromosomal rDNA Minichromosome of Physrum Polycephalum
… sequences. A consistent structural feature, an inverted repeat at approximately -30 to -50 nucleotides, was identified in this and other rRNA transcription initiation sites examined. The transcribed regions of this rDNA minichromosome were found to be packaged into an altered, extended …
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The involvement of non-B DNA forming sequences in mediating missense mutations, micro-deletions and micro-insertions in human inherited disease
… hotspot motifs, mononucleotide runs and tandem repeats) and epigenetic marks in mediating germline missense and nonsense mutations, micro-deletions and micro-insertions causing human inherited disease and obtained from Human Gene Mutation Database (HGMD; http://www.hgmd.org) was studied in …
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Characterization and nucleotide sequence of apple mosaic virus coat protein gene
… of a 25,085 Mr. The sequence contains several inverted repeats that could form hair-pin structures. In addition, two palindromic sequence were found in the ORF with a third palindrome in the 3$\sp\prime$-nontranslated region. These structures may be involved in the recognition of RNA by viral …
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Genetic studies on the region downstream of the unc operon of Thiobacillus ferroxidans
… sequence homology to TnsA of transposon Tn7. Inverted repeats very similar to the imperfect inverted repeat sequences of Tn7 were found upstream of ORF3. The cloned T ferrooxidans glmS gene was successfully used to complement an E.coli glmS mutant CGSC 5392 when placed behind a vector …
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Molecular Evolution in non-bilaterian Metazoa with Emphasis on Phylum Porifera
… aufzuspüren. Hier wird dieses Gen von Inverted Repeats flankiert. Solche Inverted Repeats sind auch typisch für spezielle transposable Elemente, so dass diese Beobachtung ein Hinweis auf einen von einem Transposon verursachten Transport von einem mt Gen auf das Kerngenom darstellen …
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Identifizierung und Charakterisierung von Plasmiden verschiedener klonaler Gruppierungen in Neisseria meningitidis
… Region festgestellt, welche die beiden Inverted Repeats IR1 und IR2 enthält und dem Gen pivNG benachbart ist, das für eine Rekombinase kodiert. Bei der Repeat-Region des Gonokokkenstammes MS11-A handelt es sich nach Carrick et al. möglicherweise um eine Rekombinationsstelle. Es konnte …
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Expression, sequencing, and characterization of mannitol-1- phosphate dehydrogenase genes from Aspergillus parasiticus and Escherichia coli
… or higher eucaryotic gene promoters; however, inverted repeats were identified, which may be important for regulation of gene expression. A sequence similar to the Shine-Dalgarno sequence was found preceding the translation start codon of the A. parasiticus mtlD gene, which is important for its …
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Chromosomal Evolution of Malaria Vectors
… DNA such as transposable elements (TEs), tandem repeats (TRs) and inverted repeats (IRs). This dissertation provides physical maps for two important malaria vectors, An. stephensi and An. albimanus (Ch.2 and Ch. 3) and then applies those maps to the identification of inversion breakpoints in …
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Discovery of a Novel Metalloregular Family: Structure/Function Studies of E. Coli Rcnr
… sequences containing G-tracts flanked by AT-rich inverted repeats. RcnR binds to a pair of sites in the rcnA-rcnR intergenic region leading to DNA wrapping, and repression of both genes. The identification of this new metalloregulator family and subsequent investigation of the functional …
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DD34E DNA Transposable Elements of Mosquitoes: Whole-Genome Survey, Evolution, and Transposition
… identity between copies, and intact terminal-inverted repeats and open reading frames. One such element, AgTango, was also found in a distantly related mosquito species, Aedes aegypti, at high amino acid sequence identity (79.9%). It was discovered that Tango transposons have patchy …
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Structural determinants of mutability across cancer genomes
… these include Z-DNA, G-quadruplexes, inverted repeats that can fold in cruciforms and hairpins, direct and short tandem repeats that can mediate the formation of slipped structures and a subset of mirror repeats that fold in intramolecular triple stranded DNA also known as H-DNA. A …
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Insertion sequence IS1141: discovery, characterization, and association with Mycobacterium intracellulare colonial variation
… basepairs in length with 23 basepair imperfect inverted repeats was designated as insertion sequence IS1141. IS1141 is the first insertion sequence identified in M. intracellulare. Data base searches using open reading frames (ORF) of IS1141, identified ORFb as significantly similar to the …
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Development of broadly applicable transgenic tools for the transposon mutagenesis of the red flour beetle, Tribolium castaneum
… suppressed meiotic recombination between inverted and non-inverted regions on homologous chromosomes and can thus serve as defined balancer chromosomes. Also defined deletions/duplications were generated in D. melanogaster. Such aberrations will be crucial in other insect species, like T. …
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Beschreibung und Charakterisierung einer neuen Pathogenitätsinsel, integriert in das selC-Gen von "Locus of enterocyte effacement"-negativen, Shiga-Toxin-produzierenden Escherichia coli
… Homologie zu verschiedenen Insertionssequenzen, inverted repeats und Integrasen gefunden. Drei Leserahmen hatten eine hohe Homologie zu bereits bekannten Genen. Hierbei handelt es sich um die iha- , btuB- und espP-Gene von E. coli. Das iha-Gen kodiert für ein Adhärenz-vermittelndes Protein, btuB …
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Genetic Studies on the Circadian Clock in the Model Organism Drosophila Melanogaster
… with gene function in a tissue specific manner, inverted repeat sequences specific to the period gene were expressed in neurons responsible for circadian locomotor activity. A consistent lengthening of the circadian period was found. In accordance with a double stranded RNA mediated mechanism, …
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Studies of the genome and regulatory processes of Vibrio parahaemolyticus
… is a series of gene cassettes separated by inverted repeats that facilitate recombination events that build the integron. The integron region is further evidence of genetic differences between the two strains. The integron in the RIMD2210633 strain is comprised of 69 gene cassettes, while …
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Mechanisms of genomic stability maintenance in fission yeast
… present in the form of Mb-long, extrachromosomal inverted repeats. Finally, to elucidate the DNA damage repair mechanisms that mediate the formation of CNGs upon re-replication induction, the incidence of re-replication induced CNGs was measured in mutant strains, bearing specific repair pathways …
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Interaction of Bacteriophage Mu Middle Transcription Activator Protein Mor with Promoter DNA
… dyad-symmetrical element containing two 6-bp inverted repeats and centered at -43.5 in Pm. The goals of this study were:</p> <p>1. To test the prediction from the crystal structure of Mor that residues Y70 and Q68</p> <p>of the β-strand whose side chains extend away from the protein, make …
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