Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"invasive pneumococcal disease"”.
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Force field comparison through computational analysis of capsular polysaccharides of Streptococcus pneumoniae serotypes 19A and F
… compared. Streptococcus pneumoniae is a cause of invasive pneumococcal disease (IPD) such as pneumonia and meningitis in children under five. While there are over 90 pneumococcal serotypes only a handful of these are responsible for disease. Immunisation with the conjugate vaccine PCV7, has …
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Molecular modelling of the Streptococcus pneumoniae serogroup 6 capsular polysaccharide antigens
… Molecular Modelling methods. S.pneumoniae causes invasive pneumococcal disease (IPD), a leading cause of death in children under five. The serotypes in group 6 are amongst the most common of IPD causing serotypes. We performed structural characterization of serogroup 6 to understand the structural …
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Modelling longitudinal data on respiratory infections to inform health policy
… research questions common to several infectious diseases. The answers to these questions provide the epidemiological understanding to prevent future outbreaks, by informing public health policies such as drug stockpiling, vaccination regimes or non-medical interventions. We investigate the use of …
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Novel strategies to prevent and treat experimental pneumococcal disease
… in their ability to protect against invasive pneumococcal disease (IPD). The adult pneumococcal vaccine is composed of capsular polysaccharide from 23 of the most prevalent disease causing serotypes. Purely polysaccharide vaccines are unable to protect those most at risk; infants …
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The Pneumococcus Urinary Antigen Test Kit: Use in the laboratory for the presumptive diagnosis of pneumococcal bacteraemia
… growth on culture. Novel detection methods for invasive pneumococcal disease include PCR and antigen tests. We evaluated using a urine antigen test directly on selected blood cultures with appropriate Gram stain results, immediately after signalling positive for the rapid identification of S. …
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Respiratory Tract Infections: Aspects of Aetiology, Virulence, and Communicable Disease Control
… and mortality, in the most severe cases due to invasive pneumococcal disease (IPD; mainly sepsis and meningitis).The development and spread of resistant pneumococci are facilitated in day care centres (DCCs), which constitute an optimal environment for these processes. In Sweden, penicillin …
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A pan-genome wide association study to identify genes associated with invasive Streptococcus pneumoniae
… colonizes the human nasopharynx. The invasive pneumococcal disease occurs when isolates spread to normally sterile sites such as lungs, blood, and the central nervous system. Colonization, though, does not necessarily lead to infection. Some isolates remain in the upper respiratory …
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Bacterial colonization of the nasopharynx in paediatric patients with acute respiratory viral symptoms
Pneumococcal disease involves infections at both sterile and non-sterile sites, and accounts for considerable morbidity and mortality in Australia. Its public health significance has prompted the progressive introduction of vaccination against the most clinically significant capsular serotypes. …