Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"invasive candidiasis"”.
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D-arabinitol in the diagnosis of invasive candidiasis
Invasive candidiasis (IC) is a serious condition and timely diagnosis with early initiation of antifungal therapy is imerative for improving outcomes. Arabinitol is a sugar alcohol with two stereoisomers, D-arabinitol (DA) and L-arabintiol (LA). Several pathogenic Candida species produce DA in …
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Examining How Non-Antifungal Medications Impact Host-Fungal Interactions
<p>Invasive fungal infections (IFIs) are estimated to kill 1.5 million people each year with mortality rates remaining high (around 30-70%), despite the availability of three major classes of antifungal drugs. Furthermore, millions more suffer debilitating infections of the mucosal membranes or …
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Factors Governing Gastrointestinal Colonization of Candida albicans
… colonization levels in order to prevent invasive candidiasis in immunocompromised patients. Further, C. albicans strain-specific difference in colonization ability appears to depend on the sensitivity to these host immune effectors. The described isolates can further serve as valuable …
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Delineating the Upc2A Regulon in Candida glabrata
… glabrata is the second most common cause of invasive candidiasis. Intrinsic resistance has greatly limited the utility of the triazole antifungal, fluconazole, in the treatment of invasive fungal infection. The transcription factor Upc2 regulates the expression of sterol biosynthesis genes in …
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Investigation of Clinically Relevant Fluconazole Resistance Mechanisms in the Fungal Pathogen Candida parapsilosis
Invasive candidiasis is a severe fungal infection associated with significant morbidity and mortality, particularly among the critically ill and immunocompromised. Candida parapsilosis is the most common non-albicans species causing invasive Candida infections in pediatric and neonatal populations …
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Características clínicas, microbiológicas y desenlaces de la candidiasis invasora en adultos en un hospital de alta complejidad
Introducción: La candidiasis invasora es una infección grave, asociada a la atención de la salud y con alta mortalidad generada por Candida spp. Esta infección compromete cualquier órgano, principalmente el lecho sanguíneo. Es causada por Candida spp.; siendo más común Candida albicans, pero tiende …