Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"invasive bladder cancer"”.
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INVASIVE BLADDER CANCER - Aspects on staging and prognosis
… the prognosis for the individual patient with invasive bladder cancer is a major clinical problem. Currently, decisions regarding therapy are mainly based on tumour stage and grade, the first of which is notoriously demanding to ascertain. New molecular markers are however proposed to be of …
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Non-Coding Rnas Identify The Intrinsic Molecular Subtypes of Muscle-Invasive Bladder Cancer
… THE INTRINSIC MOLECULAR SUBTYPES OF MUSCLE-INVASIVE BLADDER CANCER</strong></p> <p>Andrea Elizabeth Ochoa, B.S.</p> <p>Advisory Professors: David J. McConkey, Ph.D. and Joya Chandra, Ph.D.</p> <p>There has been a recent explosion of genomics data in muscle-invasive bladder cancer (MIBC) to …
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Development of a Hollow-Core Fiberoptic Microneedle Device for the Treatment of Invasive Bladder Cancer
… to reduce overall hydraulic resistance. The bladder treatment study describes the fabrication and testing of the FMD for treatment of invasive urothelial cell carcinomas (UCCs). Experiments investigating the fluid dispersal of single-walled carbon nanohorns (SWNHs) in the wall of inflated, …
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The Role of microRNAs in Bladder Urothelium Development and Tumorigenesis
… may be more than one urothelial progenitor. Bladder cancer is the fifth most common cancer in the United States and the second most prevalent genitourinary malignancy. Urothelial carcinoma accounts for 90% of bladder cancers. Based on clinical and histological studies, urothelial carcinomas …
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Investigating the Mechanisms of Resistance to Dual PI3K/MTOR Inhibitor in PIK3CA Mutant Basal Like Bladder Cancer
Muscle invasive bladder cancer (MIBC) carries a poor prognosis where the overall 5 year survival ranges from 48% to 66%. To date, targeted therapies, except for immune checkpoint inhibitors have not been shown to be effective in the management of this disease, where conventional chemotherapy (i.e. …
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Effect of Systemic Versus Localized Bacillus Calmette-Guérin Immunotherapy on Bladder Cancer Progression: Novel Role for Trained Immunity
The standard of care for high-risk non-muscle invasive bladder cancer (NMIBC) involves intravesical immunotherapy with Bacillus Calmette Guérin (BCG). Unfortunately, most patients do not respond fully to this therapy, and our understanding of the immunotherapeutic effect of BCG is incomplete. The …
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Quality of Life: Socio-Demographic and Genetic Determinants As Well As Links With Cancer Outcomes
… (QOL) is an independent prognostic factor for cancer. Lung cancer is the leading cause of cancer death. Breast cancer is the most diagnosed. Bladder cancer is the most expensive cancer to treat because of its high recurrence rate. We set to perform comprehensive analyses of predictors of QOL in …
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Circulating Tumour DNA in Localised Urological Cancers
… informative biomarkers in localised urological cancers. At present, no method can accurately distinguish between indolent and aggressive prostate cancers, and men often require repeated biopsies. Patients with muscle invasive bladder cancer undergo neo-adjuvant chemotherapy (NAC) to improve …