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Showing 1 to 20 of 59 for “"intrauterine growth"”.
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Role of PABP4 in intrauterine growth restriction
… in pregnancies which exhibit intra-uterine growth restricted (IUGR) fetuses from e15.5, and an increased prevalence of late-gestational fetal death (akin to stillbirth). Stillbirth affects approximately 1 in 225 pregnancies in the UK, and IUGR is not only a major risk factor for stillbirth …
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Muscle Growth and Development in Intrauterine Growth Restricted Pigs
Intrauterine growth restriction causes impaired growth and development of mammalian fetus, and leads to long-term negative effect on postnatal growth. Among domestic animals, pigs exhibit the most severe naturally occurring IUGR and reduced postnatal muscle growth. The objectives of this research …
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Effects of dietary intervention on inflammation and intrauterine growth restriction in neonatal piglets
Intrauterine growth restriction (IUGR), a form of fetal malnutrition that leads to small for gestational age (SGA) infants, is a condition that affects 7.5 million children born worldwide. Infants affected by IUGR are more prone to lengthy hospital stays, repeated infections, and neurodevelopmental …
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Effects of 2ʹ-fucosyllactose on brain and cognitive development of intrauterine growth restricted piglets
Intrauterine growth restriction (IUGR) leads to small for gestational age (SGA) neonates, increasing risk of brain and cognitive impairments that persist into adulthood. Human milk oligosaccharides (HMO) have been postulated to exert positive effects on brain development. HMOs are the third most …
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Development in children born very preterm after intrauterine growth restriction with abnormal fetal blood flow
Delivery of fetuses with intrauterine growth restriction (IUGR) with abnormal umbilical artery blood flow in the second trimester represents a clinical dilemma. So far, no evidence based management protocols are available adressing when to deliver these fetuses. The high risk of hypoxia and fetal …
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Investigating thyroid hormone transport and regulation in chorionic somatomammotropin RNAi models of intrauterine growth restricted pregnancies
… chorionic somatomammotropin (CSH) results in an intrauterine growth restricted (IUGR) phenotype in sheep. Abnormal levels of thyroid hormones (THs) 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4, thyroxine) and abnormal expression of placental deiodinase 2 and deiodinase 3 …
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Aggressive Behavioral Phenotype in Intrauterine Growth Restricted (IUGR) Baboons Exposed to Moderate Nutrient Restriction Early in Development
… could be an association between aggression and intrauterine growth restriction (IUGR), which can result from low maternal food intake during pregnancy. The main hypotheses of this study are [1] IUGR offspring demonstrate higher rates of aggressive behavior and [2] IUGR offspring attain higher …
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Intrauterine growth restriction (IUGR) and birth outcomes in a cohort of HIV-infected pregnant women in Cape Town, South Africa
Background: Intrauterine growth restriction (IUGR) is a major contributory factor of perinatal morbidity and mortality. This suboptimal growth is associated with infants being small-for-gestational age. In addition to genetic and placental factors, maternal factors such as infection are also …
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A semiquantitative and qualitative histopathologic assessment of the effect of type II intrauterine growth retardation on the structure of the carotid bodies in fetuses and neonates
… been undertaken to investigate the effects of intrauterine hypoxia on the carotid body of foetuses. Clinically, intrauterine growth retardation has been ascribed, amongst other causes, to placental insufficiency that results in chronic hypoxia in the fetus. Intrauterine growth retardation can …
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Die Evaluierung der Dopplersonographie der Aa. uterinae in der 19.-24. Woche zur Vorhersage von Schwangerschaftskomplikationen
… included pregnancy induced hypertension, intrauterine growth retardation below 5th centile and preterm delivery before 34 weeks of gestation. Different cutoff values for bilateral RI as 70th, 80th, 90th and 95th centile were examined for the best sensitivity and the lowest false- positive …
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Axis of placental ageing in adverse pregnancy outcomes
… impacts both maternal and fetal outcomes. Intrauterine growth restriction (IUGR) is defined as the inability of the fetus to reach normal growth potential within the uterus as a result of various genetic, environmental, or placental factors. Premature ageing of the placenta in pregnancy …
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Aggregatibacter actinomycetemcomitans serotypes in gingival crevicular fluid of mothers delivering preterm.
… weight (LBW), is a direct consequence of PTB or intrauterine growth restriction, and is a major determinant of neonatal infant morbidity and mortality. The primary aim of this study was to determine if the prevalence of Aggregatibacter actinomycetemcomitans (Aa) serotypes in gingival crevicular …
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Early life origins of the insulin resistance syndrome in the aged guinea pig.
In human populations, perturbed growth in early life and ageing have been identified as risk factors for the development of Insulin resistance syndrome (IRS). The consequences of restricted prenatal growth on postnatal function have been investigated using numerous experimental models of …
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The investigation of the calcium antagonist nifedipine on fetal umbilical artery Doppler waveforms
… related to this circulation in hypertension and intrauterine growth retardation (IUGR). 2. The biokinetics of nifedipine and a review of the experiments that have been performed using the drug in human and animal models. 3. The principles of Doppler ultrasound and the literature pertaining to its …
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The role of thyroid hormones in placental development and the importance of the thyroid hormone transporter MCT8
… important for fetoplacental development. Human intrauterine growth restriction (IUGR) is associated with malplacentation and reduced fetal circulating concentration of THs. The expression of the plasma membrane TH transporters MCT8, MCT10, LAT1, LAT2, OATP1A2 and OATP4A1 was characterised in …
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The role of kisspeptin and its cognate receptor GPR54 in normal and abnormal placentation
… has been associated with preeclampsia and intrauterine growth restriction as well as other adverse pregnancy outcomes such as miscarriage, preterm birth and intrauterine death. Hypertensive disorders of pregnancy, including pre-eclampsia are one of the leading causes of maternal mortality …
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The perinatal and obstetric outcomes of triplet conceptions at Groote Schuur Hospital in the five-year period: 1 January 2012 to 31 December 2016
… miscarriage, twin to twin transfusion syndrome, intrauterine growth restriction and discordant growth, stillbirths, preterm delivery, premature rupture of membranes and low birth weight. Neonatal complications included respiratory distress syndrome or hyaline membrane disease, intraventricular …
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Wiederholungsrisiko und anamnestisches Risikoprofil bei hypertensiven Schwangerschaftserkrankungen (HES)
… HES. Perinatal complications (preterm delivery, intrauterine growth restriction, neonatal death) occuring mostly in HELLP patients and decrease significantly in the following pregnancies in all hypertensive disorders.
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Role of Chlamydia trachomatis infection in adverse pregnancy outcomes
… including controversial data on miscarriage, intrauterine growth restriction and low birth weight, however the causative mechanisms are unknown. A successful pregnancy requires normal endometrial stromal cell (ESC) decidualisation and trophoblast invasion, processes that involve chemokine …
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