Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"intranuclear positioning"”.
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BAC transgene arrays as a model system for studying large-scale chromatin structure
… chromatin, including transcription level and intranuclear positioning. Using this system, we showed that tandem arrays of housekeeping gene loci form open large-scale chromatin structure independent of their genomic integration sites, including insertions within centromeric heterochromatin. …
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Targeting a Transcriptional Activator Induces Changes in Large-Scale Chromatin Structure and Nuclear Positioning
… and large-scale chromatin structure and nuclear positioning. We have used an artificial system to target large amounts of the very strong viral transcriptional activator, VP16, to specific chromosome sites. The rationale of this approach is to use this exaggerated system to amplify effects on …
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Organization of Human Sperm Chromosomes During Pronuclei Formation
… spatial organization that includes preferred intranuclear positioning. The hypothesis of this dissertation is that sperm chromosome architecture participates in controlled transformation and activation of the paternal genome following fertilization.</p> <p>Adequate model systems are necessary …