Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 32 for “"intramuscular injection"”.
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Needle Length Required for Intramuscular Injection in Women
… to measure the subcutaneous tissue depth at four intramuscular injection sites: (1) deltoid, (2) gluteus maximus, (3) gluteus medius, and (4) lateral femoral. Pearson product-moment correlations and regression lines were computed for each of the variables. Data from the study were compared with …
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Cardiovascular components of organophosphorus-induced delayed neuropathy
… effects in hens of a single 2.5 mg/kg intramuscular injection of phenyl saligenin phosphate (PSP) into the breast muscle. Parameters were measured at 1, 3, 7, and 20 days post treatment. All hens developed clinical signs of delayed neuropathy by day 10 and these signs were maximal by …
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The effect of dietary zinc level upon the efficiency of vitellogenin synthesis by male quail
… quail during 3 weeks of treating period. After intramuscular injection with 8μmol/100g body weight of estradiol-17β, Japanese quail were sacrificed and vitellogenin (phosphoprotein) production was assessed in these birds by analyzing plasma for protein-bound phosphorus concentrations (PBP). …
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Effects of Estradiol on Leydig Cell Function and Testicular Development in the Prepubertal Bull
… were challenged at 7, 22 and 31 weeks with an intramuscular injection of human chorionic gonadotropin (hCG). Serum hormone levels were determined weekly. At 39 weeks of age, E and P calves were castrated for histologic evaluation of the testes and assessment of in vitro Leydig cell function. …
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Systemic AAV-Mediated Gene Therapy Using Epo-R76E to Protect Retinal Ganglion Cells from Optic Nerve Injury and Disease
… as a neuroprotectant. Mice received a single intramuscular injection of rAAV carrying either Epo or EpoR76E. Upon reaching peak gene expression (30 days), mice were subjected to optic nerve crush. Neuronal cell death was examined in both the ganglion cell layer and the optic nerve. Treatment …
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Studies on immunology of Leishmania mexicana
… immunity. The efficacy of DNA immunisation by intramuscular injection or using gene gun, in generating immunity to leishmania was compared. Gene gun immunisation induced more immunity to the parasite and high levels of Th1 immune response, which were detected, one week after immunisation …
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Reduction of Myocardial Stunning by in Situ Genetic Alteration of Myocytes
… and cardiac myocytes results from simple injection of DNA into muscle tissue. To test the possibility that overexpression of Superoxide dismutase (SOD) may decrease ischemia-induced reperfusion injury to myocytes, we injected a plasmid (PMTSOD) containing the sheep metallothionein promoter …
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Enabling carers to administer depot injections: an action research study
… as to why her husband could not administer depot injection. Following local and national discussion the study aims were; - to explore the elements of risk management involved in enabling carers (supportive persons) to give depot injections - to develop a training package that may be useful for …
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The effects of gene replacement therapy on respiratory and gait function in a canine model of X-linked myotubular myopathy
… three different routes of administration—local intramuscular injection of the hindlimb, isolated perfusion of the hindlimb and systemically. Systemic treatment was carried out at three different doses to determine the minimum effective dose for full preservation of function. Respiratory function …
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Perivascular cell contribution to skeletal muscle repair following physiological injury
… Adult male wild type mice received bilateral intramuscular injection of pericytes 24 hr after a single bout of resistance exercise initiated by electrical stimulation of the sciatic nerve (n=5-6/group). Mice were sacrificed 4 days post-stimulation and the tibialis anterior muscles were …
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Intranasal Immunization of Pigs with Porcine Reproductive and Respiratory Syndrome Virus like Particles Plus 2’, 3’ –cGamp Vaccigrade™ Adjuvant Exacerbates Viremia After Virus Challenge
… of vaccination could be considered such as intramuscular injection. A higher dosage of the VLPs could also be tested.</p>
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Surface Engineering of Protein Nanoparticles for Intranasal Delivery
… a promising alternative approach to invasive intramuscular injection, with additional benefits such as inducing mucosal antibodies and cellular responses to neutralize pathogens before entering systemic circulation. However, nasal secretions and mucosa are biological barriers that have been …
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Engineering Secreted Proteins for Gene Transfer and DNA Vaccination
… secreted form of GAD (SGAD55) was obtained. The intramuscular injection of plasmid DNA encoding GAD65 and SGAD55 into three-week-old NOD mice showed a dramatic reduction of development of insulitis, the first symptom of diabetes in NOD mice.</p>
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Functional recovery in young adult and aged rats following delayed, intramuscular treatment with neurotrophin-3 after focal stroke injury.
… allodynia responses.<br/>This thesis shows that intramuscular injection of AAV-NT3 improves function in elderly rats as well as in young rats, and that intramuscular infusion of recombinant NTS protein improves function in young adult rats, even when treatment is initiated 24 hours after stroke. …
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Estrogenic Effects of Genistein in Ovariectomized Gilts
… or 400 mg/day). Treatments were administered by intramuscular injection at 12-hour intervals for 10 days. Gilts were slaughtered after the treatment period. Reproductive tissues (cervix, uterus, and mammary glands) were collected, trimmed of extraneous tissue, and processed for chemical or …
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Methods of fertility enhancement and control of beef females
… The SMB treatment procedure consists of an intramuscular injection of norgestomet and estradiol valerate and a norgestomet impregnated hydron ear implant that was left in situ for 9 days. All females were artificially inseminated approximately 47 hours after implant removal. In the first …
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Cerebro-spinal fever
… in blood pressure which results, intravenous or intramuscular injection of adrenaline is useful, in order to restore the tone of the peripheral circulation. • The signs and symptoms of Cerebra-spinal Fever are due to the combination of several factors, which are all present to a varying degree in …
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BRIDGING CLINICAL, METABOLIC, AND NUTRITIONAL FINDINGS IN MOTHER¿INFANT DYADS WITH MATERNAL VITAMIN B12 DEFICIENCY IDENTIFIED THROUGH NEWBORN SCREENING
… At the first admission, before hydroxycobalamin intramuscular administration, newborns showed mean values of vitamin B12 178.78 pg/ml (SD ± 82.44), homocysteine 18.01 μmol/L (SD ± 7.48; n.v. <10), plasma methylmalonic acid 3.89 μmol/L (SD ± 3.26; n.v. 0–4), and urinary methylmalonic acid 63.46 …
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Design of novel delivery systems to probe alternative routes of administration for a self-amplifying RNA rabies vaccine
… systems to protect them against degradation upon injection and to facilitate their delivery in host cells. Among them, lipid-based delivery systems and, more specifically, lipid nanoparticles (LNPs) are efficient non-viral delivery systems for RNA and SAM vaccines. Within this thesis, a panel of …
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Lymph-targeted intradermal delivery of antiretroviral agents via dissolving polymeric microarray patches
… of therapeutic agents, but common intradermal injections come with many drawbacks. Dissolving polymeric microarray patches (MAPs) are minimally-invasive and self-disabling delivery systems that can be employed for intradermal administration of various compounds. This thesis explores, for the …
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