Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 79 for “"intraepithelial"”.
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Activation and Maintenance of Intestinal Intraepithelial Lymphocytes (IELs)
… located between the IECs that have been named intraepithelial lymphocytes (IELs). As the main lymphoid population within the intestinal barrier, IELs are thought to have an important role in intestinal homeostasis maintenance, as well as a role in intestinal inflammatory and autoimmune diseases …
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Association of the Cervical Intraepithelial Neoplasia and Human Papillomavirus Viral load
… 빛 단위의 비율로 표현하였다. 결과: 대조군과 자궁경부 상피내 종양 (Cervical intraepithelial neoplasia ; CIN) 1, CIN 2, CIN 3, squamous cell carcinoma인 각각의 군 사이에 임상적 특성에는 유의한 차이를 보이지 않았으나 CIN 등급이 높아질수록 viral load가 증가하는 양상을 보였으며 통계적으로 유의하였다. HPV viral load가 자궁경부 상피내 종양 유무를 진단하는데 대한 민감도, 특이도, 양성예측도, 음성예측도는 각각 82.9%, 37.7%, …
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Risk factors and diagnostic methods of high grade cervical squamous intraepithelial lesions /
… risk factors of high grade cervical squamous intraepithelial neoplasia (HSIL) of women residing in particular areas employing the method of questionnaire surveys. The following risk factors were identified: not getting vaccinated against flu, living in villages and other rural areas, primary …
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Overcoming Barriers to Screening for Anal Intraepithelial Neoplasia for Persons Living with HIV
… recognized screening guidelines for anal intraepithelial neoplasia (AIN). Screening for AIN stands to reduce overall incidence of anal squamous cell carcinoma through destruction of the dysplastic cells before they become cancerous. The goals of this project were to identify the patient …
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Investigating the movement of intestinal intraepithelial lymphocytes using an organoid co-culture system
… several bacteria and microorganisms. Intestinal intraepithelial lymphocytes (IELs) are T cells that are interspersed between epithelial cells, above the basement membrane. This makes them one of the first immune cells to encounter and provide defence against invasive microbes. Studies have shown …
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T-cell responses to human papillomavirus in men with anal high-grade squamous intraepithelial lesions
… a precancerous stage termed high-grade squamous intraepithelial lesion (HSIL). Unlike cervical cancer, the natural history of anal HSIL is poorly understood, and there is little evidence to inform prevention guidelines. In a retrospective audit of 574 men (73% HIV-infected) attending our anal …
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Feasibility Study of Liquid-Based Cytology for Post-Treatment Surveillance of Patients with Vulvar Intraepithelial Neoplasia
… remain the gold standard for diagnosing vulvar intraepithelial neoplasia (VIN). Vulvar colposcopy is fairly nonspecific. As a result, many women undergo unwarranted painful biopsies. Vulvar cytology, which is relatively painless, inexpensive and allows a larger area to be sampled, may likely …
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Impact of the chromatin remodeller SMARCAD1 on murine intestinal intraepithelial lymphocyte and white adipose tissue biology.
… remodeller SMARCAD1 on murine intestinal intraepithelial lymphocyte and white adipose tissue biology. Chromatin remodelling factors use the energy of ATP hydrolysis to drive the movement of and/or affect molecular changes to the nucleosome. One such factor, SMARCAD1 (SWI/SNF-related …
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Cellular immune responses to human papillomavirus (HPV) type 16 at the cervix of women with HPV-associated squamous intraepithelial neoplasia
… reported to be associated with 84% of cervical intraepithelial neoplasia (CIN). HPV type 16 (HPV-16) is the most prevalent HPV type associated CIN and cervical cancer with ±56% of women with cervical disease being infected with HPV 16. Yet studies have shown that 47-85% of CIN regressed, …
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Histological outcome of atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (asc-h) papanicolaou smears diagnosed at Groote Schuur hospital
… Cells, cannot exclude High grade squamous intraepithelial lesion (ASC-H) category is said to carry a positive predictive value for High grade Squamous Intraepithelial neoplasia (HSIL) that lies between Atypical Squamous Cells of Uncertain Significance (ASC-US) and HSIL. Aim: The aim of this …
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Comparison of viral load values of Hybridcapture-II test between pre- and post- conization in patients with grade II/III cervical intraepithelial neoplasia
고등급 자궁경부 상피내종양의 원추절제술 전후의 인유두종바이러스 검사의 임상적 의의를 알아보고자 하였다. 아주대학교 병원에서 상피내종양으로 원추절제술을 받은 환자들 중 수술 전후에 인유두종바이러스 검사 (Hybrid capture-II)를 시행한 환자들을 대상으로 하여 임상양상과 재발 유무를 비교 분석하였다. 102명이 설정된 기준에 적합하였다. 이들 중 수술 시 절제 경계면의 종양침범 유무를 알 수 있는 경우는 64명이었다. 재발의 유무는 수술 후 인유두종바이러스 검사 결과 및 수술 시 경계면의 종양침범과 상관관계를 가지고 …
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Long-term outcomes of women treated for high-grade squamous intraepithelial lesions at a University Hospital colposcopy unit in South Africa. A 5-year retrospective cohort study
… study of all the women with high grade squamous intraepithelial lesion (HSIL) Pap smears seen at GSH colposcopy clinic between 01 January 2010 and 31 December 2015. The outcome measures were; diagnostic concordance between cytology, colposcopy and histology, large loop excision of the …
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A Study of Histopathologic Outcomes of Women With Cryotherapy-Ineligible lesions on Cervicography
… the association between high grade cervical intraepithelial neoplasia (CIN 2+) and individual acetowhite cryotherapy-ineligible lesion types, as determined by cervicography.Design: a cross sectional study Setting: Gynecologic Cancer Prevention Unit of the University Teaching Hospital, …
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A Study of Histopathologic Outcomes of Women With Cryotherapy-Ineligible lesions on Cervicography
… the association between high grade cervical intraepithelial neoplasia (CIN 2+) and individual acetowhite cryotherapy-ineligible lesion types, as determined by cervicography.Design: a cross sectional study Setting: Gynecologic Cancer Prevention Unit of the University Teaching Hospital, …
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Evaluating the role of PLGF and VEGFR-1/ Flt-1 in the development of cervical intraepithelial neoplasia and invasive cervical carcinoma in the background of HIV infection in women living in South Africa
… underlying progression from low-grade squamous intraepithelial lesions (LSIL) to high grade intraepithelial lesions (HSIL) and invasive carcinoma remain incompletely understood. Angiogenesis within the tumour microenvironment, mediated by placental growth factor (PLGF) and its receptor vascular …
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The battleground of two Infections and a cancer: Human Papilloma Virus, premalignant lesions of the cervix and their interaction with Human Immunodeficiency Virus in southwestern Nigeria
… in detecting cytology - diagnosed squamous intraepithelial lesions. Studies II and III utilised data generated in Study I to determine the interaction between HIV infection, antiretroviral therapy, and precancerous lesions of the cervix. Study IV, a cross-sectional study, assessed the …
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Molecular Mechanisms and Antigen Receptor Requirements for Lymphocyte Adaptation to Intestinal Tissues
… in the lamina propria. However, CD8αα-expressing intraepithelial CD4+ T cells (CD4- IELs), which also exhibit anti-inflammatory properties and depend on similar environmental cues, reside in the epithelium. Using intravital microscopy, we find distinct cell dynamics of intestinal Tregs and …
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Genetic and Molecular Studies of Endometrial Cancer
… precursor of type II carcinomas, endometrial intraepithelial carcinomas were observed. Subsequently, the role of dysfunctional telomeres in endometrial cancer development was investigated in the mouse by conditionally inactivating Pot1a, a key component of the shelterin complex that stabilizes …
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