Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"intimin"”.
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Mechanisms Associated with Attachment of Escherichia coli O157:H7 to Lettuce Surfaces
… extracellular proteins (curli, O157-antigen, and intimin) known to influence attachment of E. coli to intestinal cells were evaluated for their physicochemical properties and ability to adhere to cut edge and whole leaf lettuce. Escherichia coli O157:H7 strains included: 0018, 43894 and 43895 …
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Investigating bacterial adhesion proteins as tools for controlling bacteria-surface interactions
… cells. A set of novel adhesins based on the beta-intimin system were designed using protein engineering techniques. In this series, a bacterial cellulose-binding module, and the peptide-binding domain of the M. primoryensis ice- and diatom-binding adhesin were separately fused to the end of the …
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Studies of EHEC and the complement system in renal diseases
… symptoms in a mouse model using mutant strains. Intimin and the presence of the type III secretion system effectors were necessary for intestinal colonization and virulence in mice. The presence of Shiga toxin induced intestinal mucosal cell death by apoptosis, which could thus allow EHEC …
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Post-Transcriptional Regulation of Virulence Genes by GlmY and GlmZ in Enterohemorrhagic E. Coli
… translocation and insertion of the translocated intimin receptor (Tir) into the host cell membrane. The bacterial adhesin intimin then binds to Tir, allowing EHEC to tightly adhere to the host cell’s membrane (109). Tir also indirectly recruits another bacterial effector EspFu, which induces …
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Shiga Toxin-Producing Escherichia coli: a Public Health Challenge in the Pre-Harvest Stage of the Farm-to-Table Continuum
… encoding Shiga toxins, enterohemolysin, and intimin. By targeting these genes, highly sensitive molecular-based techniques help detect potentially harmful STEC. Persistent carriers and environmental contamination may be responsible for maintenance of STEC in cattle farms. Prevalence may be …
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The Characterization of Quorum Sensing E. Coli Regulators E,F, and G (Qse EFG) and Their Role in Pathogenesis
… protein, Tir, and the outer membrane protein, Intimin. Also, a prophage encoded effector protein, EspFu, is required. EHEC regulates many of its virulence genes including the AE lesion genes in response to environmental signals. Utilizing these signals allows EHEC to colonize the intestine …
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Effects of low molecular weight compounds on growth, virulence gene expression and cytotoxic activity of Shiga toxin-producing Escherichia coli O157:H7
… of the Shiga toxin genes, stx1 and stx2, and the intimin gene, eaeA, by STEC serotypes (O157:H7 and non-O157), and to investigate the effect of compound NV002 on human kidney (HK-2) cells based on the influence of the compound on the expression of major virulence genes in E. coli O157:H7 strains. …
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Untersuchungen zur Regulation von Shiga-Toxin 2 und zur Attenuierung von enterohämorrhagischen Escherichia coli
… Die Enterohämolyse sowie die Expression von Intimin waren verstärkt. Die Expression der typischen EHEC-Virulenzfaktoren war demnach in der leuX-Mutante nicht reduziert. Der Einfluß von leuX auf die Expression dieser Faktoren war offensichtlich nicht auf eine Translationsreduktion durch die …
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Funktionelle Charakterisierung potentieller Pathogenitätsfaktoren aus Pseudomonas aeruginosa mittels biochemischer und evolutiver Methoden
… Wechselwirkungen mit Partnern via Fusion an das Intiminprotein der äußeren Membran auf der Oberfläche von E. coli Zellen zu präsentieren. Es konnte gezeigt werden, daß eine Zelloberflächenexposition eine Translokation des jeweiligen Pa ssagierproteins durch die äußere Membran in einem …