Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"intestinal development"”.
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The Role of Cdx in Intestinal Development
… Cdx4, are known to play essential roles in many developmental processes including neural tube closure, axial elongation and patterning the anterior-posterior axis of the developing embryo. Cdx1 and Cdx2 are both expressed in the endoderm of the embryo and persist throughout adulthood in the …
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Thyroid in intestinal development during atlantic salmon smoltification
… present PhD thesis gives a novel insight into intestinal morphology, intestinal SW acquisition, and involvement of TH in intestinal development during the freshwater (FW) and the development of competence for the SW phase. Here we used a winter signal (Photoperiod manipulation) and functional …
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The Soy Isoflavone, Genistein, as a Modulator of Intestinal Development
… present in soy infant formulas inhibited intestinal cell proliferation both in vitro and in vivo, which may have implications for the intestinal health of infants and requires further investigation.
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Regulation of Intestinal Development and Function in Early-Life Pigs
… stimuli. The early postnatal phase is a critical developmental window, during which diet transitions and stress can have lasting effects on overall health and productivity. Attenuated growth performance and feed efficiency may exacerbate production losses and have significant economic implications …
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Early nutrition affects intestinal development and immune response in the neonatal piglet
… factors against pathogens, modulating immune development, and perhaps even providing nutrients for brain development (Bode, 2012). Prebiotics are routinely added to infant formula to mimic the actions of HMOs. In addition to increasing rates of formula feeding, the proportion of infants being …
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Short-Chain Fatty Acids and Glucagon -Like Peptide-2 Enhance Intestinal Development and Adaptation
… weight. These infants have a higher risk for intestinal dysfunctions indicating the use of total parenteral nutrition (TPN) to meet their nutritional needs. Despite its benefits, TPN is associated with many complications; hence, treatments aimed at minimizing the need for TPN are necessary. …
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Influence of Incubation Conditions on Turkey Poult Intestinal Development and Susceptibility to Poult Enteritis
… embryonic incubation may impact organ growth and development, development of immunocompetency, post-hatch performance and may predispose poults to enteric disease. The objective of the first study was to provide a baseline of responses to incubation conditions so that further studies could be …
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Left, Right, and Center: A Novel Midline Barrier Separates Asymmetric Extracellular Matrix During Intestinal Development
Correct intestinal morphogenesis depends on the early embryonic process of gut rotation, an evolutionarily-conserved program in which a straight gut tube elongates and forms into its first loops. The gut tube requires guidance to loop reproducibly, however. The dorsal mesentery (DM) connects the …
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Effects of Dietary Fiber on Neonatal Intestinal Development and Resistance to Salmonella Typhimurium Infection in Piglets
… symptoms in piglets, maintained intestinal structure and function, enhanced innate and adapted immune response, and its addition to formula, could provide a cost-effective means to prevent and/or reduce bacterially-induced diarrheal diseases in neonates.
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Effects of supplemental osteopontin on intestinal development and serum antibody responses to rotavirus vaccination in piglets
… despite the fact that natural milk improves intestinal development and immune system functions in neonates (Donovan et al., 1994; Field, 2005) relative to milk formula. Characterization of the biological effects of such components is important for optimal production of infant milk formulas to …
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Intestinal Development and Gene Expression of Piglets Suckling Sows Transgenic for Human Insulin-Like Growth Factor-I
We have shown that piglets suckling IGF exhibit structural and functional changes similar to those observed in piglets receiving formula supplemented with IGF-I. The location and timing of the response to IGF-I differs from previous studies. Insulin like growth factor-I appeared to act via the type …
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The Influence of Necrotic Enteritis, Environmental Factors, and Genetics on Intestinal Development Pathways and Disease Occurrence in Broiler Chickens
… in feed has allowed for reemergence of intestinal diseases that diminish animal welfare and producer economics. Alternative mechanisms to preventing disease are therefore required. The objective of this dissertation was to examine factors that contribute to chicken development and health …
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OVEREXPRESSION OR REDUCED BIOAVAILABILITY OF VEGF DURING MOUSE POST-NATAL INTESTINAL DEVELOPMENT ALTERS THE PROLIFERATION OF INTESTINAL STEM CELL PROGENITOR CELLS
… we investigated how VEGF affects the post-natal development of the intestinal epithelial by either overexpressing VEGF or by reducing the bioavailability of VEGF with the overexpression of soluble VEGF receptor (sFLT-1) within the gastrointestinal tract. After three weeks of VEGF overexpression, …
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The effects of 2’-fucosyllactose and Bifidobacterium longum subspecies infantis supplementation on growth, intestinal development and immune development and function in piglets
… has a naïve immune system and immature gastrointestinal system. Breastfeeding is the optimal feeding mode to stimulate the development of these systems in the infant due to the bioactive nature of breastmilk. However, globally many infants rely on infant formula to meet their nutritional …
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Oral Insulin-Like Growth Factor-I and Development of the Small Intestine in the Neonatal Piglet
Given that IGF-I modulation of intestinal development did not lead to an increase in overall piglet growth, we conclude that the effects of IGF-I in the normal, healthy neonate are modest. However, since IGF-I stimulates intestinal growth and development without undesirable systemic effects, it may …
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Delayed access to feed affects broiler small intestinal morphology and intestinal cell ontogeny
… to feed (DAF) has been found to inhibit small intestinal development, compromising growth of the chick. To further understand the impact of DAF on small intestines at the molecular level, many developmental genes that regulate intestinal development were investigated. The objective of this …
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RDH10 is Necessary for Initial Vagal Neural Crest Cell Contribution to Embryonic Gastrointestinal Tract Development
… are absent from variable lengths of the gastrointestinal tract due to a failure of neural crest cell (NCC) colonization or development, leading to megacolon and/or the failure to pass meconium. Enteric neurons are derived from neural crest cells (NCC); hence HSCR is associated with incomplete …
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Multi-omic characterisation of Barrett’s oesophagus reveals a molecular continuum in the progression to oesophageal adenocarcinoma
… oesophagus (BE) is the main risk factor for the development of oesophageal adenocarcinoma (OAC) yet only 0.4%/year of non-dysplastic (ND) BE cases progress to cancer (Bhat et al., 2011). In this thesis I present the first comprehensive, multi-omics study comparing indolent, non-progressors with …
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Butyrate-Induced Expression of Proglucagon: Implications for Enteroendocrine Signaling and Intestinal Growth
While the gastrointestinal tract is primarily recognized for its digestive and absorptive capacity, it is also the largest endocrine organ in the body. There are a number of different types of endocrine cells in the gut which have the ability to mediate nutrient-gene interactions. Of interest for …
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Butyrate-induced expression of proglucagon: implications for enteroendocrine signaling and intestinal growth
While the gastrointestinal tract is primarily recognized for its digestive and absorptive capacity, it is also the largest endocrine organ in the body. There are a number of different types of endocrine cells in the gut which have the ability to mediate nutrient-gene interactions. Of interest for …
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