Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"intestinal damage"”.
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Response of early weaned pigs to an escherichia coli challenge and their absorption to ovalbumin or xylose as influenced by creep feeding
… the E. coll challenge, but had little effect on intestinal absorption of ovalbumin and xylose.
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Moderate Acute Malnutrition: Inflammatory Response, Microbiota, and Potential Treatments
… signs of impaired fatty acid metabolism, intestinal damage, and liver dysfunction. Markers of these dysfunctions (iFABP and LBP) may have potential as markers of recovery from MAM. Studies in a mouse model of MAM corroborated the chronic inflammatory state and metabolic dysfunction …
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Concomitant Suppression Of Both Cox-1 And Cox-2 Is Not Sufficient To Cause Gastroenteropathy Associated With Chronic Nsaid Use
… these drugs are associated with many gastrointestinal and cardiovascular adverse events, including intestinal bleeding, ulceration, stenosis, myocardial infarction, and stroke. It has long been accepted that NSAID enteropathy is an unavoidable consequence of simultaneously inhibiting both …
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Gut Microbiome Dysbiosis Exacerbates Malaria Severity in Ugandan Children
… renal clearance likely increases levels of intestinal uric acid, which supports the growth of uricase producing bacteria such as Enterobacteriaceae. Furthermore, Enterobacteriaceae associated with multiple complications of SM such as coma, severe anemia, acidosis, acute kidney injury (AKI), …
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Investigating the movement of intestinal intraepithelial lymphocytes using an organoid co-culture system
… intestine, which is lined by a single layer of intestinal epithelial cells, is the main site of nutrient absorption. It is continuously exposed to food antigens, and also several bacteria and microorganisms. Intestinal intraepithelial lymphocytes (IELs) are T cells that are interspersed between …
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Computational Approaches To Anti-Toxin Therapies And Biomarker Identification
… toxins. These toxins, TcdA and TcdB cause severe intestinal damage. As Clostridium difficile harbors considerable antibiotic resistance, one treatment strategy is to prevent the tissue damage that the toxins cause. The catalytic glucosyltransferase domain of TcdA and TcdB was studied using …
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Studies of EHEC and the complement system in renal diseases
… order to gain access to the circulation it first damages the intestinal mucosa. The mechanism of damage and the bacterial factors involved were addressed. Abundant cell death by apoptosis was demonstrated in HUS patients. EHEC virulence factors were correlated to the intestinal damage and symptoms …
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Novel insights into the interaction between iron and curcumin and its physiological consequences
… is limited leading to oxidative stress in the intestinal mucosa and gastrointestinal (GI) symptoms that eventually compromises patient adherence to treatment. Iron supplementation in endurance athletes may be even more challenging as intense endurance exercise upregulates hepcidin, the master …
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The effect of high-fiber diets on nutrient utilization and intestinal morphology of growing pigs
… effects of dietary fiber on mineral balance and intestinal.morphology of growing pigs. Fiber sources were added to corn-soybean meal diets at levels which increased neutral-detergent fiber levels by 6 to 8%. In experiment 1, 10% oat hulls (OH) decreased Ca (P<.06) and Zn (P<.01) balances of pigs …
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L'infiammazione intestinale nell'animale sperimentale come modello per lo sviluppo di nuovi farmaci: ruolo della via tachichininergica nelle malattie infiammatorie intestinali
… receptors, termed NK1, NK2 and NK3. SP modulates intestinal motility and enteric secretion, acting preferentially through the NK1 receptor. SP neural network and NK1 receptor expression are increased in patients with inflammatory bowel disease, and similar changes were observed in experimental …
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Roles of Cytosolic Nucleic Acid Sensors in Cancer and Infection
… of STING-deficient mice exhibited significant intestinal damage and overt proliferation with increased levels of pro-inflammatory cytokines during early stages of tumorigenesis, uncovering an unexpected and important role for STING in mediating protection against colorectal tumorigenesis.</p> …
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The role of organelle crosstalk in a Drosophila model of Parkinson’s disease
… of PD. PD patients experience gastrointestinal issues that often precede the onset of motor symptoms, implicating the gut-brain axis in the pathogenesis of this disease. Likewise, in pink1 mutants, mitochondrial dysfunction leads to cell death and proliferation in the Drosophila …
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Effects of dietary feed additives on the performance and gastrointestinal health of broilers exposed with coccidial spores and varying litter conditions
… oocysts from contaminated litter, resulting in intestinal damage, impaired nutrient absorption, and reduced growth performance, which contribute to economic losses for poultry producers. Conventional control methods, including vaccines, ionophores, and other anticoccidials, have limitations, …
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Development of Novel Methods to Study Host-Microbe Interactions In The Larval Zebrafish Gastrointestinal Tract
… pose significant challenges to the study of intestinal physiology and pathology. Zebrafish larvae, possessing optical transparency and genetic tractability, offer an accessible and clinically relevant model for investigating dynamic events in the intestine via time-lapse imaging. In the first …