Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 33 for “"intestinal bacteria"”.
-
Functional genomics of motile commensal intestinal bacteria
Flagella confer upon bacteria the ability to move and are therefore organelles of significant bacteriological importance. The innate immune system has evolved to recognise flagellin, (the major protein component of the bacterial flagellar filament). Flagellate microbes can potentially stimulate the …
-
Effects of subtherapeutic doses of antibiotics on poultry intestinal bacteria
… the growth of poultry by affecting the intestinal flora. The bacterial flora of the small intestine of turkey poults was extensively analyzed in an attempt to correlate changes in populations with growth response. Lactobacillus species comprised almost 100% of the duodenal flora of …
-
Activation of proestrogens from hops by human intestinal bacteria: conversion of isoxanthohumol into the potent phytoestrogen 8-prenylnaringenin
… other phytoestrogens and related with variable intestinal bacterial metabolism, the goal of this work was to investigate whether intestinal bacteria also determine the final activity of hop phytoestrogens by combining batch incubations with SHIME, rat and human studies. Batch incubations learned …
-
Impact of intestinal bacteria on the anatomy and physiology of the intestinal tract in the PRM/Alf mouse model
Introduction: Intestinal bacteria influence gut morphology by affecting epithelial cell proliferation, development of the lamina propria, villus length and crypt depth [1]. Gut microbiota-derived factors have been proposed to also play a role in the development of a 30 % longer intestine, that is …
-
ENZYMOLOGY AND MOLECULAR BIOLOGY OF BILE ACID 7alpha- AND 7beta- DEHYDROXYLATION BY THE INTESTINAL BACTERIA CLOSTRIDIUM SCINDENS AND CLOSTRIDIUM HYLEMONAE
The collective microbial genomes within our gut(microbiome) represent a powerful metabolic force, leading many authors to call our GI flora an "organ within an organ", and the metagenomic sequencing of our microbiome, "the second human genome project". Bile acids, endogenously produced by the host …
-
Characterization of Bacterial Metabolites Involved in Host Pathogen Resistance
<p>The intestinal microbiome can mediate host resistance to enteric pathogens by modulating host immunity or by directly inhibiting pathogen growth and virulence. Although the abundance and diversity of bacterial metabolites in the intestine is appreciated, the majority of intestinal bacteria and …
-
The bi-directional relationship between gut microbiota and autoimmunity
… immune responses produced against host tissue. Intestinal bacteria are directly impacted by instances of inflammation brought on by autoimmunity. The complicated nature between autoimmunity and bacterial modulation demonstrates a bi-directional relationship. Here, we utilize experimental …
-
Investigating the Influence of Fresh and Aged Garlic Extracts on the Biosynthesis of Trimethylamine N-Oxide
… influenced by the metabolic activity of the intestinal bacteria on dietary precursors including L-carnitine. Dietary supplementation of bioactive garlic phytochemical allicin has recently been suggested to reduce the formation of TMAO precursor molecule trimethylamine (TMA) from L-carnitine …
-
Epithelial Cell Autophagy in Antibacterial Defense of the Small Intestine
… relationship can break down when resident bacteria opportunistically invade the intestinal barrier, leading to pathologies such as inflammatory bowel disease (IBD), and bacteremia. As a result, epithelial cell innate immune responses play an essential role in preventing bacterial invasion …
-
Studies on the metabolism and excretion of chlorine chloride
… while incubating choline chloride with the intestinal contents of rabbits, in an attempt to correlate the rate of urinary excretion of trimethylamine with the rate of its production from choline by intestinal bacteria.</p><p>3. A study of the rate of trimethylamine formation when choline is …
-
Starch Source, Fraction, and Processed Form Affect in Vitro and in Vivo Digestion and Glycemic Responses in Dogs
… starches, or the fermentative activity of small intestinal bacteria that can influence rate and extent of starch digestion and its subsequent utilization within the GIT. Therefore, the objectives of the experiments conducted were to (1) determine the concentrations of starch and starch fractions …
-
The Elasmobranch-Microbe Relationship: Trimethylamine n-oxide Synthesis, Urea Hydrolysis, and Microbe-Osmolyte Interactions in the Atlantic Stingray, <i>Dasyatis sabina</i>
… urease and Tmase are found in many species of bacteria. Therefore, I hypothesized that intestinal bacteria are responsible for urease and Tmase activity in elasmobranchs. Absent dietary nitrogen sources, I evaluated the effects of reduced intestinal microbiota on osmoregulation in Atlantic …
-
Variability in fecal microbial drug deglucuronidation
… and xenobiotics, such as drugs. Several intestinal bacteria produce various β-glucuronidase enzymes, which catalyze deglucuronidation of compounds formed during UDP-glucuronosyltransferase (UGT) mediated phase II metabolism. Deglucuronidation can result in the formation of an inactive, …
-
Interactions between salmonella typhimurium and human gut bacteria
… the interaction between Salmonella and the gut bacteria to elucidate the elements that influence the ability of the pathogen to overcome the colonisation barrier mediated by the gut microbiota and why Salmonella can persist in ‘healthy’ individuals in a carrier state after infection. In this …
-
A study of diet and health in the elderly; the gut microbiota as a source of bioactive agents
… persons is increasing rapidly. Diet and the intestinal microbiota independently and jointly contribute to health in the elderly. The habitual dietary patterns and functional microbiota components of elderly subjects were investigated in order to identify specific effector mechanisms. A study …
-
Investigating the protective effects of intestinal GABA[subscript A] receptor activation on an animal model of Multiple Sclerosis
… nervous system (CNS) and by some species of intestinal bacteria. GABAA receptors are found not only in the CNS, but also in T cells and within the intestines. Past studies have indicated that GABA can have an anti-inflammatory effect and production of GABA by gut bacteria decreases in …
-
The Role of the Intestinal Microbiota in Inflammatory Bowel Disease
… environmental, and microbial factors. The intestinal microbiota is crucial for IBD induction and complex shifts in microbiota composition occur in IBD, but disease has not been consistently associated with presence or absence of a specific microbe. It is thus controversial whether …
-
Host Factors That Influence Coxsackievirus B3 Replication and Pathogenensis
… pathogens that initiate infection in the gastrointestinal tract. They follow a fecal-oral route of transmission and are spread by contamination of food, water, or contact between individuals. Furthermore, enteric viruses also cause significant morbidity, mortality, and economic burdens yearly. …
-
Studies of Sulfur Reduction of Taurine and Taurine-Conjugated Bile Acids by Bile acid 7α-Dehydroxylating Bacteria
… the liver from cholesterol and secreted into the intestinal lumen to aid in emulsification of dietary lipids and lipid-soluble vitamins. The indigenous intestinal microflora modify bile acids, producing up to 20 unique bile acid metabolites. The 7α-dehydroxylation of the bile acids is the most …
-
Antioxidants and natural anti-cancer agents in the large bowel and the influence of intestinal microbial fermentation.
… development of a chemostat designed to simulate bacterial interactions that occur in the large bowel using porcine faeces and dissolved oxygen at concentrations within the range detected in the large bowel. This demonstrated the effects of antioxidants and oxygen on intestinal bacteria using …
Page 1 of 2