Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 662 for “"interrogation"”.
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Interrogation of fibre optic sensors
… described in this thesis was to investigate the interrogation of fibre optic sensors using "off the shelf optical components and equipment developed mainly for the telecommunications industry. This provides a cost effective way of bringing fibre optic sensor systems to within the price range of …
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Optical fibre sensors and their interrogation
… uses of said gratings as optical sensors and the interrogation of optical sensors using tilted fibre Bragg gratings. This thesis presents the most detailed study of type IA gratings performed to date and provides the basis of a dual grating optical sensor capable of independently measuring strain …
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Interrogation and control of mammalian transcription
… reliable and generalizable tool for genome-wide interrogation of gene function and interaction in diverse biological processes. Recently, we have extended the utility of the SAM system to enable bimodal control through the use of modified, truncated deadRNAs (dRNAs) (Dahlman, et al., Nature …
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Torture and coercive interrogation: A critical discussion
This thesis aims to explore why torture, deemed illegitimate by the Western world for more than a century, has resurfaced as a topic of debate, and persists despite its formal prohibition. It also endeavours to shed light on the main issues involved in the ‘torture debate’. To do so, it begins by …
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Through-wafer interrogation of MEMS device motion
Microelectromechanical systems (MEMS) have been the focus of many research groups because of their wide variety of uses in sensing and actuation applications. A fundamental barrier facing designers of next generation MEMS is the inability to access accurate, real-time microstructure positional …
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Strain sensor using fiber bragg grating interrogation
… of strain sensor using Fiber Bragg Grating (FBG) interrogation. Studies on fiber optic sensors reported have mainly focused on FBG wavelength-based monitoring method by using optical spectrum analyzers (OSA). Although FBG has better strain sensitivity measurement, however there have some …
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SPINS : spectral phase interrogation using nonlinear spectra
A novel technique for ultrafast pulse measurement is presented. This technique involves only the measurement of the fundamental, second harmonic, and third harmonic (or other third-order nonlinear) spectra of an ultrafast pulse. An algorithm is employed to generate trial SHG and THG spectra based …
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Functional Interrogation Of Anti-Cancer Drug Resistance
<p>Targeted therapeutics are among the most promising approaches for treating diverse forms of malignancies. Indeed, as sequencing prices and technology continue to improve it will be possible to achieve a precise map of each individual cancer’s genomic lesions, providing insights into the best …
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Resonant cavity Fibre Bragg grating sensor interrogation
… ‘it should be possible to achieve TDM FBG sensor interrogation using an electrically switched semiconductor optical amplifier (SOA)’ is then explained. Research and development of a commercially viable optical sensor interrogator based on the resonant cavity architecture forms the remainder of …
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Organotellurium Reagents for Multiparametric Interrogation of Dynamic Biology
Population-averaged measurements (PAMs) of cells have advanced understanding of innumerable biochemical processes and continue to be routinely used in the laboratory. Despite this success, PAMs are limited in their ability to report on the precise state of important individual members of a …
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Development of the Interview and Interrogation Assessment Instrument
… scientist to assess the coercive pressures of an interrogation and risk factors for false confession. At present, there exists no standardized methods for performing this task, and each expert uses their own unstructured professional judgment. To address this lack of standardization, we have …
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Interrogation and Manipulation of the IGG FC Glycan
<p>Antibody signaling is a cardinal feature of successful adaptive immune responses. The magnitude and direction of this signaling is determined by the structure of a given antibody's fragment crystallizable (Fc) domain, which interfaces with cells of the immune system. Often considered a constant …
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Top-Down Interrogation And Characterization Of Biological Macromolecules
<p>Analytical mass spectrometry has been widely applied in the field of biomolecule identification and characterization. It provides fast, accurate and robust information relevant to the molecular mass, composition and structure of the target analytes.</p> <p>This thesis is focused on the top-down …
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"Experiencing ""Upward Bound"": An interrogation of cultural landscapes"
"This thesis addresses one of the most significant public issues facing higher education today: the recruitment and successful matriculation of low-income and minority students. These students are variously described in the literature and popular language as ""non-traditional,"" ""marginal,"" …
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Opto-fluidic neural probes for optogenetic brain interrogation
The modulation and measurement of neuro-chemical and electrical signals with high sensitivity, spatial precision on the order of neurons, and temporal precision in milli seconds is the holy grail of neuroscience. To achieve this goal, novel tools to capture neurochemical dynamics with high …
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Interrogation and engineering of RAD51:BRC repeat interactions
The maintenance of genetic information is a fundamental function of every organism. The DNA in every human cell endures thousands of lesions per day, and eukaryotes have developed a sophisticated response to tackle this damage. Double strand breaks (DSBs) are the most toxic type of DNA damage, …
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CRISPR-mediated interrogation of small cell lung cancer
… the CRISPR-Cas9 system for performing functional interrogation of SCLC.
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3-D shape interrogation by medial axial transform
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Ocean Engineering, 1995.
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Interrogation of Conscience and Audience in Shakespeare's Early Plays
Interrogation scenes, in which a character confronts and questions himself, or in which inquisitors question a character in a dramatic dialogue, are dramatizations of confrontational interrogatory discourse. This thesis explores the relation between such scenes in Shakespeare’s early plays and …
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Functional Genomics Based Interrogation of Cell-Fate Determination Pathways
The Hedgehog (Hh) and Wnt signal transduction pathways are master regulators of embryogenesis and tissue renewal and represent anticancer therapeutic targets. Using genome-wide RNA interference screening in murine cultured cells, I established previously unknown associations between these signaling …
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