Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 165 for “"interneurons"”.
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The Diversity of Cortical Interneurons
… and memory consolidation. The cortical interneurons are key elements of the cortical system. These interneurons stabilize networks, but at the same time they also add non-linear effects to the excitatory system to make the cortical network more dynamic. To achieve this, cortical …
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Spinal interneurons in sensorimotor integration
… basic aims: (1) to investigate propriospinal interneurons connecting rostral and caudal lumbar spinal cord in the rat; (2) to investigate input properties of identified spinal interneurons interposed in different pathways; (3) to investigate cholinergic terminals in the ventral horn of adult …
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Connectivity of olfactory bulb dopaminergic interneurons
… to a large and diverse population of inhibitory interneurons that greatly outnumber the excitatory neurons. These are responsible for processing the incoming sensory signal in accordance with the wider sensory context, prior experience, and internal state, to shape its eventual perception and …
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Pyramidal tract effects on spinal cord interneurons.
Massachusetts Institute of Technology. Dept. of Physics. Thesis. 1966. Ph.D.
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The role of fast-spiking interneurons in cortical map plasticity
… in this thesis. I focused on fast-spiking (FS) interneurons, which are thought to play an important role in<br/>adult cortical plasticity. I made electrophysiological recordings in layer 2/3 to determine how inhibitory circuitry in deprived cortex is affected by whisker deprivation. The …
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Roles Of Inhibitory Interneurons In Cerebellar Cortical Processing For Oculomotor Control
… two techniques for examining the roles of interneurons in cerebellar processing. In the second, I present the results of a study of one such interneuron, the Golgi cell, which is the main type of inhibitory interneuron that regulates information flow at the input stage of the cerebellar …
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The Role of Inhibitory Interneurons in a Model od Developmental Epilepsy
… receptors found on the vertically-projecting interneurons but not on those inhibitory cells that control horizontal spread of activity. Our results suggest that the network effect of activating these interneurons is altered in malformed, epileptogenic cortex.
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THE CRAYFISH VISUAL SYSTEM: INTRACELLULAR STUDIES AND MORPHOLOGIES OF IDENTIFIED INTERNEURONS
… periodic excitatory synaptic input. Other visual interneurons were impaled and dye-filled. These included, (a) Phasic light-on cells, (b) Tonic light-off cells, (c) Phasic light-on and -off cells, (d) Optic tract motion detectors, (e) Nonspiking light-on neurons, (f) Lamina monopolar cells, and …
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Connectivity of dI3 Interneurons In the Development of Mice Spinal Cord
… be determined. dI3 INs, a class of dorsal spinal interneurons, have positioned themselves as key mediators of reflexive grasping in early development and grasping in adult mice. The first aim of the study focused on determining the developmental time point at which the PGR disappeared. Our studies …
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Circuitry and function of layer 1 interneurons in the medial entorhinal cortex
… this research includes the examination of local interneurons and their tight control over the firing patterns of excitatory cells, such as layer 2 parvalbumin- and somatostatin-expressing interneurons. However, the contribution of interneurons in layer 1 has been overlooked, even though it likely …
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The Giant Interneurons of The American Cockroach: Morphology and Physiology During Walking
Made available in DSpace on 2015-05-14T15:08:31Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7913419.PDF: 4101227 bytes, checksum: b5b0d57bf640b52d20d69fed43f61c3f (MD5) Previous issue date: 1978
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Experience-dependent dendrite remodeling of GABAergic interneurons in the adult visual cortex
… shown that dendritic arbors of inhibitory interneurons in superficial layer 2/3 can remodel in the adult cortex. Here, we investigated the role of these structural rearrangements during experience-dependent adult plasticity. Using in vivo two photon imaging, we monitored intemeuron …
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Abnormal cortical activity leads to misallocation of GABAergic interneurons in the mouse neonatal brain.
Aivojen kehityksen aikana GABAergiset hermosolut, joita kutsutaan myös interneuroneiksi, kulkeutuvat tangentiaalisesti aivokuoren eli korteksin ulkopuolelta subpalliumista aivokuorelle eli palliumiin. Aivokuorelle hajaantumisen jälkeen, interneuronit aloittavat radiaalisen migraation kohti …
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Dopaminergic Inputs to the Amygdala: Differential Innervation of Interneurons and Convergence With Cortical Afferents
… shown to influence the activity of BLC GABAergic interneurons, which differentially control the activity of pyramidal cells. However, little is known about how dopaminergic inputs interface with different interneuronal subpopulations in this region. To address this question, dual-labeling …
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Modulation of Prefrontal Cortex activity and sociability by local interneurons expressing corticotropi-releasing hormone
… types: excitatory pyramidal cells and inhibitory interneurons. Their neurochemical diversity and complex organization into interconnected laminar and columnar circuits imbues the cortex with countless computational and functional possibilities. At the behavioral level, changes in the molecular …
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Potassium channels for high-frequency action potential generation in GABAergic interneurons of Rat Hippocampus
… of Kv channels expressed in orien-alveus (OA) interneurons in the hippocampal CA1 region, a major class of dendritic inhibitory interneuron. The main results are as follows. First, the macroscopic K+ current in OA interneurons consists mainly of a fast delayed rectifier (57 ± 5), a slow delayed …
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Entwicklung eines strukturtreuen passiven Kabelleitermodells eines inhibitorischen Interneurons im Gyrus Dentatus des Hippokampus der Ratte
… Axons konnte das Strom-Spannungs-Verhalten des Interneurons mit einem passiven Kabelleitermodell mit Ri=68 Ohm.cm, Rm=10081 Ohm.cm2 und Cm=0.69 µFcm-2 beschrieben werden, das den gemessenen Eingangswiderstand mit einer Abweichung von 4 wiedergab. Bei Nichtberücksichtigung des Axons ergaben sich …
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Investigating the Transcriptional Regulation of PTF1A and the Function of PRDM13 to Specify Dorsal Spinal Interneurons
Transcriptional regulation is a fundamental process required for cell fate specification. During neural development, complex interactions of diverse transcription activators and repressors regulate lineage specific programs. The multitudes of neuronal subtypes generated during development is …
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Endogenous modulators of hyperexcitability in epilepsy: electrophysiological and optogenetic delineation of neuropeptide Y mechanisms in interneurons
… network activity. Perisomatic-targeting interneurons comprise those inhibitory cell types that form synapses onto the perisomatic region of target cells, an area including the cell soma, proximal dendrites and axon initial segment. Thanks to the strategic location of their targets, …
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Cell death of reelin secreting nNOS positive GABAergic interneurons in the hippocampus of P301L trangenic mice
Reelin은 세포외 기질 당단백질로서 초기 뇌의 발달 과정에서 신경세포의 이동에 있어서 중요한 역할을 한다. 또한, 성인 뇌의 겉질과 해마에 있는 GABA성 신경세포에서 발현하여 시냅스 가소성과 기억을 조절한다. Reelin을 발현하는 GABA성 신경세포의 subtype들 중에서 해마에서는 neuronal nitric oxide synthases (nNOS)를 발현하는 GABA성 신경세포가 가장 높은 비율로 존재하고 있다. 이러한 GABA성 신경세포의 생존에 있어서 Tau의 인산화가 중요한 역할을 담당하고 있으며, 그렇기 때문에 …
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