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Showing 1 to 20 of 79 for “"internal standard"”.
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A PROPOSED NEW INTERNAL STANDARD FOR FREE, GLYCOSYLATED AND TOTAL PYRIDINIUM CROSSLINKS QUANTIFICATION IN HEALTHY WOMEN AND CHILDREN URINE: VALIDATION OF AN HPLC-FLUORESCENCE METHOD
… are often compromised by the lack of an adequate internal standard allowing to eliminate errors occurring during sample preparation and analytical measurement. In spite of extensive literature, important points for crosslinks measurement have not been solved: 1) the choice of an adequate internal …
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Quantitative Determination of Acetylsalicyclic Acid and Acetaminophen by Q-NMR (Quantitative Nuclear Magnetic Resonance) Technique
… of compounds but to develop a method an internal standard of known concentration is required. We are using q-NMR (quantitative NMR) to quantitatively analyze acetylsalicylic acid and acetaminophen by Proton-NMR using diethyl ether as an internal standard. The area of NMR signals shows a …
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Characterisation of the Microbial Community in Indoor Environments: a Chemical-Analytical Approach
… 13C-labelled cyanobacterial cells was used as an internal standard for the first three markers (13C-labelled 3-hydroxytridecanoic acid from labelled Pectinatus cerevisiiphilus was used as an alternative internal standard to improve quantification of the 3-hydroxy fatty acids) and …
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Method Transfer for Gas-Chromatography Ion Mobility Spectrometry from Laboratory to Industrial Instrumentation
… events during manufacturing. The current gold standard method of microbial culturing, such as the dip-slide method, of analysing such events have a feedback time of around 48 hours which is not compatible with modern manufacturing processes. The need for a more efficient detection system is …
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Thin layer chromatography-matrix assisted laser desorption ionisation-mass spectrometry of pharmaceutical compounds.
… nature of the silica gel layer was corrected by internal recalibration on selected matrix ions during the scanning of the TLC plate. To enhance the signals recorded directly from a TLC plate the use of an extraction solvent prior the matrix application was explored. Further improvements in …
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Quantitative Analysis by Room-Temperature Phosphorescence
… pharmaceutical preparations. A combination of standard addition and internal standard techniques along with sophisticated instrumental and mathematical techniques were developed to improve the precision and accuracy of the RTP methods.
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Improvement and Development of Analytical Forensic Methods: Arson Investigation and Drug Detection in Fingerprints and Hair
… of evaporated gasoline samples using the internal standard di-n-decyl sulfide. This study shows that by using the internal standard, di-n-decyl sulfide, and the changes that occur in the gas chromatograms of gasoline samples that are evaporated, forensic chemists can assist arson …
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METHOD DEVELOPMENT OF STANDARD DILUTION ANALYSIS ON MOLECULES AND DISSOLUTION STUDIES OF IBUPROFEN TABLETS ALONG WITH COMMON BEVERAGE CONSTITUENTS
<p>The United States Pharmacopeia sets the standards for the manufacturing, storage, and analysis of medicinal formulations. One analysis, dissolution testing evaluates the rate at which the medicinal formulation forms a solution to predict <em>in vivo</em> drug release. Dissolution testing on …
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Inductively coupled plasma mass spectrometry with a twin quadrupole instrument using laser ablation sample introduction and monodisperse dried microparticulate injection
… ratio 63Cu+/65Cu+ is measured with a relative standard deviation (RSD) of 0.26%. Transient signals for single laser pulses are also obtained. Copper isotope ratio measurements for several laser pulses are measured with an RSD of 0.85%;Laser ablation (LA) is used with steel samples to assess the …
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Development of liquid chromatography-mass spectrometry protocols for quantification of imidacloprid in pig urine and for analysis of 5α-cyprinol sulfate metabolism in zebrafish
… investigating complex systems. LC/MS is the gold standard for resolving metabolites and end-products, but the results obtained from LC/MS are not necessarily standardized and reproducible; individual LC/MS protocols must be fine-tuned for every laboratory and for every unique experiment. Depending …
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Reversed-Phase Liquid Chromatography Tandem Mass Spectrometry And Elisa Determination Of Caffeine As A Marker For Sewage Contamination Of Wilgreen Lake
… method using 13C3-labeled caffeine as the internal standard was adapted from known methods and employed to determine and correct the recovery of native caffeine in water samples. The presence in the lake of seven other human pharmaceutical compounds (carbamazepine, sulfamethoxazole, …
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Organochlorine Pesticide Residue in Fish Fillets From Lake Springfield, Missouri
… 0.5 ppm of hexachlorobenzene was added for an internal standard. The solution was diluted to the mark and the organochlorine pesticide residues were determined by gas chromatography with electron capture detection. The average recoveries of the tested organochlorine pesticides for this method …
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Study of the Mechanism of the Coal Analysis by Laser-Induced Breakdown Spectroscopy
… the atomic line of Si I 288.2nm is chosen as the internal standard line, and the internal standard curves of C I 247.9nm, H I 656.3nm and O I 777.4nm are obtained and the calibration results are good. Moreover, in order to avoid the disturbtion of the analysis of the O element from the air, the …
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Detection and Imaging of Neurotransmitters in Rodent Brain Tissue Using FMP-10 and ZnO Nanoparticle Matrices with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry
… we evaluated deuterated GABA (GABA-d6) as an internal standard to achieve precise and reproducible quantitation of molecules.
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Modeling of an upper Midwest forest boundary layer and vehicle indoor air quality
… General Motors, and Chrysler to develop a global standard for vehicle indoor air quality test methodologies. An initial evaluation of materials to validate test and analysis process has been completed. In addition to establishing the identity of a material for an internal standard, a VOC specific …
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Prizidilol : analytical methods and in vitro metabolism by hepatic enzymes
… at different rates of prizidilol and of the internal standard. The SK & F assay might therefore be less sensitive and precise than necessary. Secondly, use of the complexing reagent, quinolin-3-al, leads to greater sensitivity of detection than the reagent, anisaldehyde, previously employed. …
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Analysis of the effects of BrdU on DLKP human lung cancer cells by two-dimensional difference gel electrophoresis and mass spectrometry
… a Cy-2 labelled mixture of both samples as an internal standard. Using DIGE technology, the statistically significant comparisons of each protein abundance was made over three biological replicates. 43 protein spots were identified as differentially regulated. Among the 43 protein spots, 25 …
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Absorption, Distribution and Excretion of Oxytetracycline and Tetracycline in Female Beagles
… performance liquid chromatography utilizing an internal standard. The average biologic half-life of oxytetracycline was 6.4 hours, whereas that of tetracycline was 13.7 hours following intra-arterial administration (10 mg/kg body weight). The half-life of tetracycline was decreased to 8.2 hours …
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Analysis of Nucleosides and Nucleotides in Milk and Infant Formula
… elution, UV detection, and quantitation by an internal standard technique. A single-laboratory validation was performed, with recoveries of 92–101% and repeatability of 1.0–2.3%. An extension study demonstrated the expansion in scope to a wider range of different infant formula products …
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Identification of pyruvate decarboxylase/indole pyruvate decarboxylase gene family members from Arabidopsis thaliana.
… directly using indole carboxaldehyde as an internal standard. This procedure failed, however, to detect IPA in the presence of plant protein extracts; thus, a coupled in vitro reaction with aldehyde dehydrogenase that produced IAA from IPA was developed, and the IAA was quantified using …
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