Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 29 for “"interleukins"”.
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ANAGRELIDE E FATTORE DI CRESCITA FIBROBLASTICO-2 (FGF-2) NELLA TROMBOCITEMIA ESSENZIALE
… janus kinase V617F mutation and inflammatory interleukins in patients with essential thrombocythemia,
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PTSD and Immunological Correlations Of Attention and Working Memory in Gulf War Illness
… that GWI diagnosis, followed by pro-inflammatory interleukins, would have on reported levels of fatigue. Although there was not a statistically significant relationship between GWI and the PASAT scores, there was an emerging trend showing GWI as a meaningful effect. The secondary analyses …
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Role of biological mediators in periodontal healing responses
… mediators induce the healing process, such as interleukins, PDGF, TGF-b, IGF- 1, FGF-2, VEGF, and EGF. Non-coding RNAs have been found to be associated with inflammatory reactions including periodontal diseases. The important functions of cytokines and the gene expression levels in regulating …
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Induktion von Sekundärstrukturen durch den Einbau von Alanyl-PNA in Peptide und Proteine
… β-Faltblattes. Es konnte anhand des humanen Interleukins 8 gezeigt werden, dass der Einbau von Alanyl-PNA durch die Technik der native chemical ligation in größere Peptide möglich ist. Hierfür wurde der N-terminale Thioester 31 des humanen Interleukins hIL8(1-55) durch Expression des …
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Autosomal random asynchronous replication is analogous to X-chromosome inactivation
… receptors, immunoglobulins, T-cell receptors, interleukins, natural killer-cell receptors, and pheromone receptors. Random asynchronous replication of DNA in S-phase represents an epigenetic mark that often parallels monoallelic expression. All randomly monoallelically expressed genes …
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Relationship of General and Health-related Anxiety and Worry to Markers of Inflammation in Women with Advanced Cancer
… and blood was drawn to measure inflammation, interleukins (IL), interferons (IFN) and tumor necrosis factors (TNF; IL-2, IL-4, IL-6, IL-10, IL-12, IFN-¿¿, TNF-¿¿, Granulocyte Macrophage Colony Stimulating Factor, Vascular Endothelial Growth Factor). Results indicated anxiety was positively …
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The role of kisspeptin and its cognate receptor GPR54 in normal and abnormal placentation
… and immunological factors such as TNF alpha, interleukins and TGFβ have been shown to be involved in the control of trophoblast invasion. Our knowledge of the molecular details of pregnancy is unfortunately limited to in-vitro experiments and animal studies. Recently kisspeptins and their …
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The role of miRNA-486-5p in hair growth and the hair follicle immune privilege
… with inflammatory chemokines, cytokines and interleukins. Taken together, these data suggest that miR-486-5p plays a protective role in the pathogenesis of AA by maintaining anagen phase and preventing the IP collapse.
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A materials-based approach for localized delivery of cancer immunotherapy
… in the clinic. Inflammatory cytokines such as interleukins-2, 12 and 15 promote potent anti-tumor immunity, but systemically administered cytokines are also highly toxic. In this thesis, we engineered cytokines with a peptide tag containing multiple phosphoserine (pSer) residues, through …
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Understanding protease-mediated host-pathogen interactions in <i style="">Proteus mirabilis</i>
… lines <i>in vitro</i> shows that it degrades interleukins (ILs)-6 and -8 and putatively disarms protease-activated receptors (PARs) 1 and 2 (via enzyme-linked immunosorbent and calcium mobilisation assays, respectively). These cytokines and receptors are heavily involved in pro-inflammatory …
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The effects of E-cigarettes on pulmonary inflammation and inflammasome activation
… which result in the processing of capsase-1, interleukins 1ȕ and 18, along with gasdermin D, leading to inflammatory cell death called pyroptosis. As E-vapour has been shown to have pro-inflammatory effects on pulmonary cells, it is possible that vapours or vapour components could lead to …
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OPTIMIZING DIAGNOSTIC ACCURACY IN CANINE URINARY TRACT INFECTIONS: FUTURE DIRECTIONS TO REDUCE ANTIMICROBIAL MISUSE IN VETERINARY PRACTICE
… gelatinase-associated lipocalin (uNGAL), urinary interleukins 8 and 6, urinary xanthine oxidase, and urinary myeloperoxidase. Among these, urinary interleukin-8 and urinary xanthine oxidase are identified as the most promising disease markers, highlighting the need for further research, …
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Organ Specific Vascular Response to Fibrosis Affects Breast Cancer Metastatic Organotropism
… such as TGFβ, HIF1α, TNFα, PDGF, VEGF, FGF, interleukins and other growth factors that are known to be pro-tumorigenic. Clinical and basic science research has shown that fibrosis presents an environment that favors tumor growth, such as hepatocellular carcinoma being commonly preceded by …
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Effetto pro-ossidante e pro-infiammatorio degli ossisteroli in cellule intestinali: attività modulatoria della frazione fenolica del vino
… activity, inhibiting the release of the two interleukins. Finally, we evaluated the signaling pathways modulated by oxysterols and wine phenolic extracts with the aim of clarifying the molecular mechanism involved in the antioxidant and antinflammatory activity. For this purpose the possible …
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POPULATION GENETIC APPROACHES FOR THE STUDY OF COMPLEX TRAITS: FOCUS ON INFECTIOUS AND AUTOIMMUNE DISEASES
… such as those encoding blood group antigens and interleukins/interleukin receptors. Several of these latter genes have evolved in response to parasitic worms, but a subset of disease alleles for inflammatory bowel disease and celiac disease have increased in frequency in response to …
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Major traumatic injury : serum cytokine biomarkers as predictors of poor clinical outcome
… other immune cells using secreted cytokines. Interleukins are a large class of cytokines, which are involved in systemic inflammation and immune system modulation by stimulating humoral or cell-mediated immune responses. They play an important role in fighting infection and diseases. …
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Salmon In Pregnancy Study (SIPS): the effects of increased oily fish intake during pregnancy on maternal and cord blood fatty acid composition, cord blood immunity and atopy outcomes in infants at 6 months of age
… not significantly affected. CBMC production of interleukins-2, -4, -5, and -10 and tumour necrosis factor-? was lower in the salmon group. There was no effect of salmon on the atopic outcomes assessed at 6 months.
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Cytokine secretion in glioblastoma patients
… and P<0.001, respectively). In contrast, Th2 interleukins IL-(4) and IL-(10) were strongly expressed in both peripheral lymphocytes and glioma cell cultures (P<0.05 and P<0.001 respectively). Immunohistochemical localisation of IL-6, IL-8, COX, IL-lO, VEGF (vascular endothelial growth factor) …
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Arming adoptively transferred T-cells with drug-loaded nanoparticles for cancer immunotherapy
… of supporting adjuvant drugs such as interleukins, chemotherapy, and other immunomodulators, but these adjuvant treatments are often accompanied by serious toxicities and may still fail to optimally stimulate lymphocytes in all tumor and lymphoid compartments. Here we propose a …
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Exploring In Vitro and In Vivo Pharmacology of Echinacea Purpurea (L.) Moench
… coronavirus (CoV) and using cytokine assays for interleukins IL-6 or IL-8 in airway epithelial cells. Test tube experiments were sought to be confirmed in organotypic tissues and upon peroral administration of EF ex vivo, whereas bio-availability of alkylamides in the extract was investigated to …
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