Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 45 for “"interleukin 8"”.
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Understanding the role of interleukin-8 (IL-8) in canine osteosarcoma metastasis
The student, Matthew Dowling, accepted the attached license on 2018-06-20 at 22:06.
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Role of interleukin-8 monomer-dimer equilibrium and glycosaminoglycan interactions in neutrophil recruitment
… (GAG) for recruiting target cells. Interleukin-8 (IL-8) is a proinflammatory chemokine, recruits neutrophils as a host response to infection and tissue injury.. An imbalance in the recruitment process has been attributed to a variety of autoimmune and inflammatory diseases. Knowledge …
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Investigating Interleukin – 8 and TGF Beta as early biomarkers predicting poor clinical outcome in major trauma
Trauma is a leading cause of death and disability. Globally, traumatic injury is the main cause of death under the age of 45. Recent studies from the UK report a demographic change in major trauma. The most common mechanism of traumatic injury is falling from less than 2 meters, with the primary …
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Inhibition of Monocyte Chemotaxis and Chemokine Macrophage Inflammatory Protein-1 Alpha, and Interleukin-8 Secretion by Lipopolysaccharide Isolated from Periodontal Pathogens
… inflammatory protein 1‑alpha (MIP‑1α) and interleukin 8 (IL‑8) both of which have been characterized as potent monocyte chemoattractants. IL‑8 has potency as a chemotactic agent equal to that of C5a. It is a pro-inflammatory mediator of gingivitis and a mediator of the inflammatory …
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Primary Myelofibrosis, Post-Erythremia Vera and Post- Essential Thrombocythemia Myelofibrosis - Impact of Inflammatory Cytokines (Interleukin 6, Interleukin 8) and Regulators of Iron Metabolism (Hepcidin) in The Pathogenesis of Anemic Syndrome // Първична, пост-еритремична, пост-тромбоцитемична миелофиброза - участието на инфламаторни цитокини (interleukin 6, interleukin 8) и регулаторите на железния метаболизъм (хепсидин) в патогенезата на анемичния синдром
Миелофиброзата (МФ) е клонална хематологична неоплазия с хетерогенна клинична изява, прояви на фибротично заместване на кръвотворенето, костно-мозъчна недостатъчност, екстрамедуларна хемопоеза, ексцесивна спленомегалия и наличие на тежък анемичен синдром. Подозиран фактор в развитието на анемия при …
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Childhood Maltreatment is Associated with Adult Depression: Is Inflammation to Blame?
… examined whether pro-inflammatory biomarkers (interleukin-6, interleukin-8, c-reactive protein, and tumor necrosis factor alpha) mediate the association between various types of childhood maltreatment (physical abuse, sexual abuse, emotional abuse, physical neglect, emotional neglect) and adult …
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Immunomodulatory effects of lactic acid bacteria on human intestinal epithelial cells and macrophages in the context of a pro-inflammatory challenge
… Tumor Necrosis Factor α was assayed by ELISA for interleukin-8 (IL-8). Granulocyte-macrophage colony stimulating factor (GM-CSF) production was assayed by ELISA in the HT-29 cell line. Strain-dependent differences were observed in the ability of viable bacteria and spent de Mann-Rogosa- Sharpe …
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Effects of CXCL8 Overexpression on Tumor Cell Proliferation and Migration in an HNSCC Cell Model
… cytokines known as chemokines. CXCL8 (Interleukin-8), a CXC ELR+ Chemokine mainly responsible for neutrophil chemoattraction, has beenimplicated in increased tumor proliferation, migration and angiogenesis. The current studytests the effects of CXCL8 on the tumor proliferation and …
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Intestinal Inflammatory Responses to the Indigenous Microbiota
… HT-29 cells with L. plantarum 299v increased interleukin-8. (IL-8) mRNA expression above levels observed for cells treated with TNF-alpha alone. The ability of TNF-alpha-to upregulate CD14 and Toll-like receptor (TLR) expression and thereby enhance IL-8 mRNA expression in response to L. …
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Induktion von Sekundärstrukturen durch den Einbau von Alanyl-PNA in Peptide und Proteine
… β-Faltblattes. Es konnte anhand des humanen Interleukins 8 gezeigt werden, dass der Einbau von Alanyl-PNA durch die Technik der native chemical ligation in größere Peptide möglich ist. Hierfür wurde der N-terminale Thioester 31 des humanen Interleukins hIL8(1-55) durch Expression des …
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A description of the pharmacokinetics of first line anti-tuberculosis drugs and adjunctive corticosteroid therapy in the pericardial compartment and their effect on cytokine profiles in the pericardial compartment of patients with tuberculous pericarditis
… associated with 83% reduction in median plasma interleukin-6 (p=0.0360), a 50% reduction in median plasma interleukin-8 (p=0.0300) and a 50% reduction in median pericardial interleukin-8 (p=0.0400). Prior to administration of glucocorticoids, the pericardial cortisol/ cortisone ratio was twice …
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Polyunsaturated fatty acids and immune cell functions
… macrophage inflammatory protein-1a (MIP-1a) and interleukin-8 (IL-8) production from PHA-or LPS-stimulated PBMC compared with baseline. It also significantly decreased cell surface expression of CD36+, CD54+ and CD62L+ on monocytes. In contrast, there was no association between LA-rich corn oil …
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Oxidative Modifications of Apolipoprotein(a): Implications for Proinflammatory and Prothrombotic Roles of Lipoprotein(a) in the Vasculature
… by which the oxPC moiety on apo(a) stimulates interleukin-8 (IL-8) production in macrophages. Targeted mutagenesis was used to determine a role for the KIV10 strong lysine binding site (sLBS) in the covalent addition of the oxPC moiety on apo(a) and identified the site of covalent oxPC …
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Behavioral alterations in rat offspring following maternal immune activation and CXC chemokine receptor antagonism
… that elevated maternal levels of the chemokine interleukin- 8 (IL-8) during MIA contribute to the neurodevelopmental alterations underlying the disorder. The present experiments used an animal model of neurodevelopmental disorders to study the effects of MIA and chemokine receptor antagonism on …
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Functional genomics of motile commensal intestinal bacteria
… pro-inflammatory, as assessed by measurement of interleukin-8 (IL-8) secretion from human intestinal epithelial cell lines. For L. ruminis, this IL-8 secretion required signalling through Toll Like Receptor 5. A model for the regulation of flagellum-biogenesis in L. ruminis was inferred from …
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Die Bedeutung leukozytärer Subpopulationen für die Arteriogenese im Kaninchenhinterlauf
… nach Femoralarterienligatur entweder PBS, MCP-1, Interleukin-8 (IL-8), Neutrophil-Activating-Protein-2 (NAP-2) oder Lymphotactin (Ltn) mittels Minipumpen lokal in das kollaterale Gefäßsystem. Während NAP-2 relativ selektiv auf Granulozyten wirkt, übt IL-8 auch einen deutlichen Effekt auf …
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Local Inflammatory Responses in Pseudomyxoma Peritonei
… from 10 PMP specimens were immunostained for interleukin 6 (IL-6), interleukin 8 (IL-8), interferon inducible protein 10 (IP-10) and monocyte chemotactic protein 1 (MCP-1). Effects of IL-6 and IL-8 on cell growth were determined using recombinant human cytokines and the human mucinous …
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OPTIMIZING DIAGNOSTIC ACCURACY IN CANINE URINARY TRACT INFECTIONS: FUTURE DIRECTIONS TO REDUCE ANTIMICROBIAL MISUSE IN VETERINARY PRACTICE
… gelatinase-associated lipocalin (uNGAL), urinary interleukins 8 and 6, urinary xanthine oxidase, and urinary myeloperoxidase. Among these, urinary interleukin-8 and urinary xanthine oxidase are identified as the most promising disease markers, highlighting the need for further research, …
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Psychoneuroimmunology and Chronic Pain
… first study to describe increased CSF levels of Interleukin-8 (IL-8) in a population of majority Failed Back Surgery Syndrome chronic pain patients (F (1, 36) = 14.89, p < 0.001, partial η<sup>2</sup> = 0.293). Gender (F (1,6) = 7.782, p = 0.565), socioeconomic status (r = -0.823, p = 0.012) and …
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