Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"interleukin 6 receptor"”.
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Genetic association study of interleukin 6 receptor and liver X receptor in systemic lupus erythematosus
… of pathogenic autoantibodies. The human interleukin 6 receptor (IL6R) consists of 2 membrane-bound glycoproteins interacting with IL6, which is a multifunctional cytokine essential to the regulation of the immune response and acute-phase reaction. Liver X receptor alpha (LXRA, NR1H3) and …
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Der humane lösliche Interleukin-6-Rezeptor: Reinigung aus Plasma, Charakterisierung und Nachweis der von einer alternativ gespleißten mRNA translatierten Form
The human soluble interleukin-6-receptor: Purification from plasma, characterization and identification of an isoform generated through alternative splicing Soluble receptors for cytokines are soluble forms of their membrane counterparts which bind their ligands with similiar affinities to those of …
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Characterisation of cytokine secretion in malignant gliomas
… (G-CSF), soluble human epidermal growth factor receptor 2 neural (sHER2neu), soluble interleukin-6 receptor alpha (sIL-6R alpha), platelet-derived growth factor - AABB (PDGF-AABB), platelet and endothelial cell adhesion molecule (PECAM-1), stem cell factor (SCF), prolactin, soluble vascular …
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Investigation of chemokine expression and modulation following traumatic brain injury
… such as the human neutrophil chemokine, interleukin-8 (IL-8/CXCL8; a functional homologue of MIP-2/CXCL2), MCP-1/CCL2 and soluble interleukin-6 receptor (sIL-6R) to contusion enlargement has not been investigated. In this thesis, I investigated chemokine expression and modulation both in …
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Herstellung und Charakterisierung hochaffiner Inhibitoren für die Zytokine IL-6 und LIF basierend auf den Liganden-bindenden Domänen ihrer Rezeptor-Untereinheiten
… cancer. While the importance of fused cytokine receptors for the treatment of dysregulated cytokine production has already been noticed, their mode of action has not been studied in detail. This should be carried out in the present study for the IL-6 inhibitor IL-6 receptor fusion protein …
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Oxidative Stress and Inflammation in the Heterogeneity of Metabolic Health
… applied. Biomarkers included IL-6, soluble IL-6 receptor, C-reactive protein, coenzyme Q10, oxidized CoQ10, markers of oxidative damage, antioxidant capacity, and advanced glycation end products. Dietary patterns, physical activity, and gut microbiota composition were also evaluated. The findings …