Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"interkinetic nuclear migration"”.
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Nuclei on the Move - Physical Aspects of Interkinetic Nuclear Migration
… In this dissertation, we focus on the process of interkinetic nuclear migration (IKNM). IKNM takes place in cells of so-called pseudostratified epithelia (PSE) during development. In these tissues, the nuclei of cells move in a cell cycle dependent manner and position themselves in a specific …
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Interplay between interkinetic nuclear migration and cell fate determination in the developing zebrafish retina
… of the neuroepithelium during the process of interkinetic nuclear migration (IKNM). The precise role of IKNM in creating the organized diversity of neuronal tissues is the topic of continued and vigorous investigation. Therefore, we employed long-term, rapid imaging of whole zebrafish retinas …
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Distinct Roles for Dynein Regulatory Proteins NudE and NudEL in Brain Development
… requires the careful balancing of proliferation, migration, and differentiation. The cellular machinery coordinating these events includes molecular motor proteins such as dynein. Regulation of dynein activity is particularly important, since it is the major microtubule minus-end directed motor in …
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Spatiotemporal dynamics of cell division in intestinal homeostasis
… exit. Post-mitotic separation is facilitated by interkinetic nuclear migration and selective tethering to the basement membrane during mitosis. Importantly, these mechanisms are altered in tissue carrying mutations in Adenomatous polyposis coli (Apc), highlighting its importance for normal tissue …
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A Reductionist Approach to Modeling Human Corticogenesis
… self‐organization in radial progenitors, interkinetic nuclear migration, as well as requirement for Notch signaling for progenitor maintenance, all of which are hallmarks of human neural progenitors in vivo. Region‐specific marker analysis, we conclude that in vitro hPSC‐ derived neural …