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Showing 1 to 20 of 26 for “"intensity modulated radiation therapy"”.
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Automating Intensity Modulated Radiation Therapy Treatment Planning by using Hierarchical Optimization
<p>The intensity modulated radiation therapy (IMRT) optimizes the beam’s intensity to deliver the prescribed dose to the target while minimizing the radiation exposure to normal structures. The IMRT optimization is a complex optimization problem because of the multiple conflicting objectives in it. …
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Intensity Modulated Radiation Therapy (IMRT) versus Conventional Methods in Treatment of Breast Cancer
Made available in DSpace on 2017-07-06T18:48:10Z (GMT). No. of bitstreams: 3 Garada_Masab_H_MS.pdf: 25651236 bytes, checksum: 73bdf7e5f39d5df868694b4da036d02f (MD5) Garada_Masab_H_MS_ABS.pdf: 430262 bytes, checksum: 605229f2df5957921ac144e978f18848 (MD5) license.txt: 4813 bytes, checksum: …
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A sensitivity-driven greedy approach to fluence map optimization in intensity-modulated radiation therapy
Intensity-modulated radiation therapy (IMRT) is a state-of-the-art technique for administering radiation to cancer patients. The goal of a treatment is to maximize the radiation absorbed by the tumor and minimize that absorbed by the surrounding critical organs. Since a plan can almost never be …
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Assessment of Collimator Jaw Optimization In Reducing Normal Tissue Irradiation With Intensity Modulated Radiation Therapy
… normal tissue dose reduction in step-and-shoot intensity-modulated radiation therapy (IMRT) on the Varian 2100 platform by tracking the multileaf collimator (MLC) apertures with the accelerator jaws.</p> <p><strong>Methods: </strong>Clinical radiation treatment plans for 10 thoracic, 3 pediatric …
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Evaluation of Intensity Modulated Radiation Therapy (Imrt) Delivery Error Due to Imrt Treatment Plan Complexity and Improperly Matched Dosimetry Data
<p>Intensity modulated radiation therapy (IMRT) is a technique that delivers a highly conformal dose distribution to a target volume while attempting to maximally spare the surrounding normal tissues. IMRT is a common treatment modality used for treating head and neck (H&N) cancers, and the …
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Adaptive Intensity Modulated Radiation Therapy Planning Optimization with Changing Tumor Geometry and Biology Enforcing Both Cumulative and Fraction Size Dose Constraints
<p>Intensity Modulated Radiation Therapy (IMRT) is a modern technique of delivering radiation treatments to cancer patients. In IMRT technology, intensities must be chosen for the many small unit grids into which the beams are divided to produce a desired distribution of dose at points throughout …
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Intensity modulated radiation therapy and arc therapy: validation and evolution as applied to tumours of the head and neck, abdominal and pelvic regions
Intensiteitsgemoduleerde radiotherapie (IMRT) laat een betere controle over de dosisdistributie (DD) toe dan meer conventionele bestralingstechnieken. Zo is het met IMRT mogelijk om concave DDs te bereiken en om de risico-organen conformeel uit te sparen. IMRT werd in het UZG klinisch toegepast …
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Construction of a model for the improved planning of MCO-informed VMAT in RayStation using a knowledge base of clinical IMRT-MCO treatment plans
Intensity Modulated Radiation Therapy (IMRT) is a type of external beam radiation therapy that has proven effective at treating many cancers. A related therapy type, Volumetric Modulated Arc Therapy (VMAT), has the potential to provide comparable dose coverage to tumor sites while better sparing …
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Optimization under uncertainty in radiation therapy
… robust approaches to managing uncertainty in radiation therapy treatments for cancer. In the first part of the thesis, we study the effect of breathing motion uncertainty on intensity-modulated radiation therapy treatments of a lung tumor. We construct a robust framework that generalizes …
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Development and application of a multi-modality inverse treatment planning system
The introduction of intensity-modulated radiation therapy (IMRT) opened new possibilities for the treatment planning process. Most of the existing treatment planning (TP) tools for the IMRT are focusing on the use of photons for the treatment. To achieve a very high computional speed only …
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Temporally Feathered Radiation Therapy under Uncertainty
This thesis focuses on radiation therapy planning through novel stochastic optimization models that account for biological heterogeneity and uncertainty in organ-at-risk (OAR) responses. Building on the temporally feathered radiation therapy (TFRT) strategy, we develop a personalized, biologically …
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Effects of pelvic 3D-CRT versus IMRT radiation therapy on circulating pro-inflammatory cytokines in high risk Prostate Cancer patients
This study examined the effects of pelvic radiation therapy on the levels of circulating pro-inflammatory cytokines (cPIC) in high-risk prostate cancer patients, who received pelvic radiation therapy delivered either by 3-dimensional radiation therapy pelvic (3D CRT) or intensity-modulated …
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2d dose measurement using a flat panel EPID
The increasing use of intensity modulated radiation therapy (IMRT) to deliver conformal radiation treatment has prompted the search for a faster and more cost effective quality assurance (QA) system. The standard technique relies on the use of film for two-dimensional dose distribution …
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Absolute Dose Verification in Intensity Modulated Radiation Fields
… a method for measuring the absolute dose for Intensity modulated radiation fields. An accurate verification and physical measurement of the computed absolute dose in Intensity modulated radiation therapy (IMRT) is a challenging task. There are many sources of errors associated with IMRT …
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Benchmarking and Implementation of A New Independent Monte Carlo Dose Calculation Quality Assurance Audit to ol For Clinical Trials
… a patient receives during external beam radiation therapy. Traditionally, the Radiological Physics Center has relied on measurements to assure that institutions participating in the National Cancer Institute sponsored clinical trials administer radiation in doses that are clinically …
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Radiation therapy of pediatric brain tumors : comparison of long-term health effects and costs between proton therapy and IMRT
Radiation therapy is an important component of pediatric brain tumor treatment. However, radiation-induced damage can lead to adverse long-term health effects. Proton therapy has the ability to reduce the dose delivered to healthy tissue when compared to photon radiation therapy, but this dose …
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An Evaluation of The Consistency of Imrt Patient-Specific Qa Techniques
<p>To ensure the integrity of an intensity modulated radiation therapy (IMRT) treatment, each plan must be validated through a measurement-based quality assurance (QA) procedure, known as patient specific IMRT QA. Many methods of measurement and analysis have evolved for this QA. There is not a …
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Development of A New Independent Monte Carlo Dose Calculation Quality Assurance Audit to ol For Clinical Trials
… systems (TPS) may use a number of different radiation dose calculation algorithms during the planning process. The Radiological Physics Center (RPC), tasked with ensuring clinically comparable and consistent dose delivery amongst institutions participating in NCI funded multi-institutional …
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Combining Mathematical Programming and Heuristic Methods to Solve the Multi-Objective Beam Angle Optimisation Problem in Radiation Therapy
… commonly used technique in cancer treatment is radiation therapy. Radiation therapy can be used either as a standalone therapy modality or, more often, in combination with other modalities such as surgery, chemotherapy, or immunotherapy. Radiation therapy aims to deliver the prescribed dose to …
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Improving Cervical Cancer Nodal Boost Radiation Therapy By Quantifying Uncertainties and Exploring Advanced Radiation Therapy Modalities
<p>Radiation therapy for patients with intact cervical cancer is frequently delivered using primary external beam radiation therapy (EBRT) followed by two fractions of intracavitary brachytherapy (ICBT). Although the tumor is the primary radiation target, controlling microscopic disease in the …
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