Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"integrin-FAK signaling"”.
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Microrna-200 Regulates Ecm-Dependent Β1-Integrin/Fak Signaling and Cancer Cell Invasion
… We have shown through 3D studies that the Integrin β1-collagen I contact is critical in mediating the invasive phenotype in cells with miR-200 loss or Zeb1 overexpression. Furthermore, those genetic changes enhanced the cells responsiveness to the ECM through the FAK/Src pathway. The …
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Effects of Penfluridol On Integrin-Fak Signaling and Tumor Cell Killing In Combination With Oncolytic Hsv In Glioblastoma
<p>Integrins are known to play an important role in activating multiple intracellular pathways, one of which is focal adhesion kinase (FAK). Phosphorylation of FAK can lead to the activation of various downstream signaling pathways that can increase tumor cell growth and proliferation, making it an …