Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"integrative physiology"”.
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Endurance performance : the integrative physiology of resisting fatigue
Includes bibliographical references.
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Modelling of Long and Short Term Blood Pressure Control Systems
… which can be applied to other aspects of human physiology also. A set of nonlinear grey-box models of varying complexities are developed in this thesis to model the process of salt-induced hypertension in Dahl rats. The models successfully replicate the multiphasal response of blood pressure to …
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Single Nucleotide Polymorphisms of the ATP1a2 gene and Their Effects on Blood Pressure and Other Cardiovascular Variable in African Americans and Caucasian Americans
… and Caucasian Americans. Doctor of Philosophy (Integrative Physiology), May 2007. Mutations in the 3’ – untranslated region (3’-UTR) of the ATP1a2 gene, which encodes the α2 subunit of Na+-K+-ATPases are reportedly associated with hypertension. This study was initiated: 1) to identify and to …
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Acute Nitrate Exposure Causes Proteomic Changes Consistent with the Regulation of Reactive Oxygen and Nitrogen Species
Nitrate is the most common ionic form of nitrogen in aquatic ecosystems. Although nitrate is known to affect ecosystems at high levels through eutrophication, hypoxia and loss of biodiversity, it is considered to be physiologically inert to the individual aquatic organism. To test the physiological …
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The role of the abdominal pump in tracheal tube collapse in the darkling beetle, Zophobas morio
Abdominal pumping is a widespread behavior in insects. However, there remains ambiguity surrounding the abdominal pumping behavior, both in terms of describing what exactly abdominal pumping is (i.e., if various modes of operation exist) and also what function(s) abdominal pumping serves (and if …
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The Effect of Cellular Dehydration on Glucose Regulation in Lean and Obese Females
<p>A chronically elevated vasopressin level has been associated with an impaired glucose regulation system in humans. A recent study in patients with diabetes suggested that low water intake is associated with impaired glucose regulation. The aim of this study was to examine the effect of …
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Cold Tolerance, Temperature Mediated Discontinuous Gas Exchange, and Emergence of the Blue Orchard Mason Bee (<i>Osmia lignaria</i>)
<p>The relationship between low temperatures, emergence and supercooling point of <em>Osmia lignaria </em>were the subject of this study. One hundred sixty-eight bees were subjected to 5 pre-wintering temperature treatments (two constant temperature controls - 22<sup>o</sup>C, 14<sup>o</sup>C, one …
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Cold Tolerance, Diapause and Winter Survival of the Brown Marmorated Stink Bug (<i>Halyomorpha halys</i>)
<p>The brown marmorated stink bug, <em>Halyomorpha halys, </em>is native to eastern Asia and is an invasive pest in the United States. Limited research has been done regarding the factors influencing this species’ winter survival within invaded northern regions. Cold tolerance has been previously …
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The Elasmobranch-Microbe Relationship: Trimethylamine n-oxide Synthesis, Urea Hydrolysis, and Microbe-Osmolyte Interactions in the Atlantic Stingray, <i>Dasyatis sabina</i>
<p>The elasmobranch osmoregulatory strategy is predicated on the accumulation of nitrogenous compounds, primarily urea and trimethylamine n¬-oxide (TMAO). Despite the abundance of these plasma osmolytes, it is notable that elasmobranchs appear to lack urease and TMA oxidase (Tmase), enzymes that …
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Cloning of a <i>CHLAMYDOMONAS REINHARDTII</i> Marker into a RNA Interference Construct to Test Whether the Photoreceptor Chlamyrhodopsin Is Involved in Circadian Clock Resetting
<i>Chlamydomonas reinhardtii</i>, a unicellular eukaryotic green alga, serves as a model organism to study the circadian clock in plants and animals. Rhodopsins are blue/green-light photoreceptors also found in <i>C. reinhardtii</i>. Chlamyrhodopsin (COP), the most abundant eyespot protein, was …
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Characterization of Andrenocortical Tissue Morphology, Histology, and Steroid Synthesis Among Finetooth (<i>Carcharhinus isodon</i>), Blacktip (<i>Carcharhinus limbatus</i>), Atlantic Sharpnose (<i>Rhizoprionodon terraenovae</i>), and Bonnethead (<i>Sphyrna tiburo</i>) Sharks
<p>Adrenocortical (interrenal) tissue is composed of steroidogenic cells that produce corticosteroids involved in the stress response and hydromineral balance. Previous research characterizing the elasmobranch interrenal suggests that the number of interrenal bodies that produce the single primary …
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Regulation of Endothelial Nitric Oxide Synthase in Pulmonary Myofibroblasts
<p>Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease leading to decreased lung volume and eventual respiratory failure. At present, the median post-diagnosis lifespan is between three and six years. Myofibroblasts are collagen-secreting cells essential for wound healing, but also …
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Insights Into The Therapeutic Potential of Salt Inducible Kinase 1: A Novel Mechanism of Metabolic Control
<p>Salt inducible kinase 1 (SIK1) has been considered a stress-inducible kinase since it was first cloned in 1999. Continued efforts since this time have been dedicated to characterizing the structure and function of SIK1. Such research has laid the ground work for our understanding of SIK1 action …
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Effects of Pre-Release Physical Stressors on Post-Release Success of Hatchery-Reared Spotted Seatrout
… known, comparatively little is known about its physiology, including how it responds to physical stressors associated with handling, transport, and release procedures. My research focused on the impacts of these physical stressors on the stress response (i.e., cortisol production), survival, …
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Aging and Sympathetic Neurotransmission in Two Strains of Rats that Differ in Longevity and Immune Profiles
<p>Age-related changes in sympathetic neurotransmission in immune organs may be associated with immunosenescence; however no causal relationship has been established. From previous studies in Fischer rats (F344), we have found that during middle age, sympathetic nerve activity (SNA) rises in the …
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Adding Upstream Sequence and a Downstream Reporter to the Bile Acid Inducible Promoter of <I>CLOSTRIDIUM scindens</I> VPI 12708
Bile acids in the small intestines of animals serve to breakdown fats and fatsoluble vitamins. Most of the bile acids are reabsorbed into the enterohepatic circulation, but approximately five percent of these bile acids pass into the large intestine. These bile acids are swiftly deconjugated by the …
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A PROOF OF CONCEPT FOR DETECTION OF PALATO-LINGUAL CONTACT WITHOUT INTRAORAL ELECTRODES IN A HUMAN PARTICIPANT
<p>The author of this thesis conceived and investigated an unexpected electrical signal that may not be noticed during regular electroglottography (EGG) when electrodes are conventionally placed on the anterior surface of the throat. It appears that there is a measurable electrical signal from the …