Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 205 for “"insults"”.
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Intergenerational and Transgenerational Effects of Endocrine Insults
… exposure to three groups of endocrine insults – endocrine disrupting chemicals (EDCs), synthetic glucocorticoids (sGCs), and hyperthyroidism – in two different species, humans and mice. EDCs are exogenous substances that interfere with endocrine axes to cause adverse health effects. …
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Ritual insults among middle school students: causing harm or passing time?
A significant gap in the bullying literature includes the lack of scholarship surrounding ethnically diverse populations (Espelage & Horne, 2008). This multistudy investigation examined the Black oral tradition of roasting and its relation with bullying behavior. Study 1 included data collected …
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Investigation of the Effects of Environmental Insults on Presumptive and Confirmatory Tests and DNA Degradation
… found to be affected by local environmental insults such as UV radiation, high temperatures and humidity, compromising the quality of the samples and the DNA profiles generated. This problem can be exacerbated when the environmental conditions are harsh. It is widely understood that …
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Effect of Neurotoxic Insults in Knock Out Cell Lines for the Study of Alzheimer's Disease
Η νόσος του Alzheimer’s disease (AD) είναι μια προοδευτική νευροεκφυλιστική διαταραχή που χαρακτηρίζεται από έκπτωση των γνωστικών λειτουργιών, με τη συσσώρευση πλακών β-αμυλοειδούς (Aβ) και τα νευροϊνιδιακά πλέγματα να αποτελούν τα βασικά νευροπαθολογικά της χαρακτηριστικά. Αν και η υπόθεση του …
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Impact of secondary insults on the outcome of paediatric traumatic brain injury : a retrospective cross sectional study at the Red Cross Children’s Hospital, Cape Town
Secondary insults in severe traumatic brain injury (TBI) may worsen outcome; however, these are poorly characterized in children. For example, despite the known association between intracranial pressure (ICP) and poor outcome, there are few large paediatric series on the subject, definitions vary, …
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Intracranial Monitoring after Severe Traumatic Brain Injury
… detection and amelioration of physiological insults. In this thesis, I explore cerebral insults due raised intracranial pressure, decreased cerebral perfusion pressure and impaired cerebral pressure reactivity after traumatic brain injury. In chapter 2, the importance of intracranial …
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Pro-social and anti-social effects of television viewing on adolescents: Speculations based on family situation comedy content
Researchers theorize that verbal insults within television family interactions may create images of dysfunctional families that serve as a paradigm for young viewers. This study conducted a content analysis of television programming and speculated about the possible development of antisocial …
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Multimodality monitoring in paediatric severe traumatic brain injury : the contributions of brain oxygen, transcranial doppler and autoregulation monitoring to conventional methods on monitoring
… with severe TBI is the prevention of secondary insults to the brain. This relies on conventional monitoring tools to identify patients at risk, but often these may fail to detect important secondary insults. Moreover, the therapies that are used commonly in the critical care environment all have …
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Modeling subconcussive and cumulative subconcussive impacts using a lateral fluid percusion injury device
… Thus, suggesting cumulative subconcussive insults may induce long-term damage. Investigating the etiology of subconcussive and cumulative subconcussive insults clinically is not feasible; however, understanding what correlation exists between cumulative effects of repetitive subconcussive …
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Explosive Safety with Regards to Electrostatic Discharge
… as susceptible to initiation due to mechanical insults. Plastic and foam materials are often used to protect explosives. Unfortunately, often many of these materials are dielectric materials which are susceptible to triboelectric charge transfer, or build-up of static charge, and thus, become a …
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Fighting Words: Slurs, Semantics, and the Law
… is unmatched by that of other, more commonplace insults. But what is it that makes oppressive slurs such potent verbal weapons? A commonplace view among both philosophers and legal theorists is that slurs make such potent insults because their uses convey extremely offensive, bigoted …
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Neuropathological significance of PLD1 in Alzheimer's disease and behavioral variant frontotemporal dementia
… further demonstrated the effect of amyloidogenic insults amyloid-β (Aβ) and tau in wildtype mice, implicating a role for PLD1 in synaptic deficits. Given this background, I implemented a 12-month-old 3xTg-AD mouse model; to corroborate a pathological role for PLD1 in AD where neuropathological …
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Nicotinamide Riboside Delivery Generates NAD+ Reserves to Protect Vascular Cells Against Oxidative Damage
… ability of vascular cells to withstand oxidative insults is critical to vascular health. NAD+, which drives poly (ADP-ribose) polymerase (PARP) and sirtuin (SIRT) reactions, can be compromised and strategies for overcoming this limitation in the vasculature do not exist. This study determines if …
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Culture War Commonalities: Personal Appearance in Commonwealth England
… practices could be leveraged as political insults in attempts to associate opposition with illicit fashion, this was not exclusive to any one side, nor did these insults necessarily reflect their intended target’s actual outlook. Fashion was a site of significant cultural tension and …
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Energy transfer and localization in molecular crystals
… equilibration eventually occurs even when the insults remain present. Interestingly, for strong fields these relaxation timescales are comparable to those of the initial chemical decomposition of the molecules. On similar timescales, we have studied the relaxation process of shock compressed …
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Integration and function of new neurons generated from fibroblasts and adult neural stem cells in the pathological brain
… stem cells in the SVZ and SGZ after pathological insults. We investigated how the newly generated neurons migrate and integrate in the brain. These two phenomena, migration and integration are intimately linked. Without the proper migratory cues new cells exhibit ectopic placement and aberrant …
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Mitochondrial Dynamics Alteration in Astrocytes Following Primary Blast-Induced Traumatic Brain Injury
… to respond to physiological stimuli or stress insults by adapting structure and function, which are intimately connected. Dysregulation of the protein regulator of mitochondrial fission, DRP1, and upregulation in the phosphorylation of DRP1 at the serine 616 site is reported to play a crucial …
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Evidence for the role of delta-6-desaturase in the development of cardiometabolic disease
… and attenuates associated cardiometabolic insults, and 2) Determine whether over-expression of fads2, the gene that encodes for D6D, results in altered membrane fatty acid composition and the development of metabolic insults associated with (T2D). Studies in aim 1 demonstrated that the …
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