Global ETD Search
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Showing 1 to 2 of 2 for “"insulin signaling transduction"”.
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The Novel Role of Interleukin-1 Receptor-Associated Kinase 1 in the Signaling Process Controlling Innate Immunity and Inflammation
… plays a key role in the pathogenesis of insulin resistance and the metabolic syndrome. Proinflammatory cytokines can cause insulin resistance in adipose tissue, skeletal muscle and liver by inhibiting insulin signaling transduction. Interleukin-1 receptor-associated kinase-1 (IRAK-1) is a …
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The Effect of Weight Reduction on Chronic Inflammatory Molecules and Insulin Resistance in type 2 DM
Type 2 Diabetes mellitus(DM) is characterized by insulin resistance. Recently, defects in the insulin-signaling cascade have been implicated in the pathogenesis of insulin resistance. Also obesity is a metabolic disease and insulin resistance is a pathogenesis of obesity. So obesity is correlated …