Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"insulin maturation"”.
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Mechanisms by which variants in the TCF7L2 gene increase the risk of developing Type 2 diabetes
… including glucose- and incretin-stimulated insulin secretion and β cell survival. The aim of this thesis is to elucidate the function of TCF7L2 in the β cells and explain the mechanisms by which genetic variants in TCF7L2 confer the increased risk of developing T2DM. TCF7L2 is a …