Global ETD Search
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Showing 1 to 6 of 6 for “"inositol polyphosphate 5-phosphatase"”.
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Identification and Functional Role of Myo-Inositol Polyphosphate 5-Phosphatase Protein Complexes
… through second messenger hydrolysis. Myo-inositol polyphosphate 5-phosphatases (5PTases) (EC 3.1.3.56) have unique signal terminating abilities toward the second messenger inositol trisphosphate (Ins (1,4,5)P3, InsP3). In Arabidopsis thaliana there are 15 members of the 5PTase family, the …
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Molecular Characterization and Loss-of-Function Analysis of an Arabidopsis thaliana Gene Encoding a Phospholipid-Specific Inositol Polyphosphate 5-Phosphatase
The phosphatidylinositol signaling pathway utilizes inositol-containing second messengers to mediate signaling events. The enzymes that metabolize phosphoinositides can in some cases serve to terminate the signaling actions of phosphoinositides. The inositol polyphosphate 5-phosphatases (5PTases) …
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Analisi molecolare in pazienti italiani con sindrome di Lowe
… The gene responsible for OCRL encodes an inositol polyphosphate-5-phosphatase. We performed the molecular analysis in 20 Italian patients and we detected the mutations in all the examined patients. Sixteen mutations out of twenty consisted of truncating mutations (frameshift, nonsense, …
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High throughput RNA interference based screen for the identification of genes implicated in listeria monocytogenes infection
… of the host cell. Also, we identified the inositol polyphosphate-5-phosphatase (INPP5B) that may regulate bacterial internalization by modulating actin dynamics at bacterial internalization sites as shown with oculocerebrorenal syndrome of Lowe (OCRL), whose OCRL gene shares an identical …
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Molecular characterization of signaling mechanisms in flowering transition in arabidopsis and association mapping of temperature response in floral development within glycine soja
… two approaches. 1) We will explore the role of inositol polyphosphate 5-phosphatase13 (5PTase13) in floral regulation mediated by TFL1 and FT. 2) We will take a broader view of floral regulation by examining the genome-wide effects of temperature response in flowering and maturity of Glycine …
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A Physiological, Biochemical and Structural Analysis of Inositol Polyphosphate 5-Phosphatases from Arabidopsis thaliana and Humans
The complete role of inositol signaling in plants and humans is still elusive. The plant Arabidopsis thaliana contains fifteen predicted inositol polyphosphate 5- phosphatases (5PTases, E.C. 3.1.3.36) that have the potential to remove a 5-phosphate from various inositol second messenger substrates. …