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Showing 1 to 1 of 1 for “"inner ear regeneration"”.

  1. Small-Molecule Activation of Yap for Inner-Ear Regeneration – and Beyond

    … organ growth during development and suppresses regeneration in mature organs. Using a highthroughput phenotypic screen, we have identified a potent, non-toxic, and reversible inhibitor of Hippo signaling. An ATP-competitive inhibitor of Lats kinases, the compound causes Yap-dependent …

    rockefeller Repository record for Small-Molecule Activation of Yap for Inner-Ear Regeneration – and Beyond (opens in a new tab)