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Showing 1 to 1 of 1 for “"innate viral sensing"”.

  1. The Role of HOIL 1 Ubiquitin Ligase Activity in MDA5 Antiviral Signaling

    … RIG-I-like receptors (RLRs), RIG-I and MDA5, are innate sensors of RNA virus infections that are critical for mounting a robust immune response. RIG-I and MDA5 both signal to MAVS to induce antiviral cytokine induction but respond to different viruses and are activated by distinct mechanisms. The …

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