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Showing 1 to 1 of 1 for “"inibitori di RNasi H"”.
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Characterization of the mechanism of action of new HIV-1 reverse transcriptase-associated ribonuclease H inhibitors
… the RNA strand of the RNA/DNA replication intermediate, critical to the synthesis of integration-competent double-stranded proviral DNA. Because of its essential role, RNase H is a promising target for drug development. However, despite years of efforts, no RNase H inhibitor (RHI) has yet reached …