Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 6131 for “"inhibition"”.
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Choline Inhibition of Prothrombinase
… whole plasma clotting time with a likely site of inhibition being the step that converts prothrombin (II) to thrombin (IIa).</p> <p>In order to quantitate the effects of choline on prothrombinase activity, bovine factor V and human factor II were isolated in this laboratory by established methods, …
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Inhibition of myofibroblast contraction
Although current medical procedures cannot restore complete function of a transected nerve, inserting both of its ends in a tube helps it regenerate. The regenerate is inferior to the uninjured nerve: it has a smaller diameter and poorer electrical conduction. Layers of contractile cells known as …
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Characterization of mTOR Inhibition and Autophagy Inhibition in Non-Small Cell Lung Cancer
… has been to characterize NSCLC response to mTOR inhibition and determine whether there are any molecular biomarkers that can predict response. mTOR is a central regulator of several pro-oncogenic signaling pathways and plays a role in cell growth, proliferation, metabolism, and inhibition of …
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Inhibition of pancreatic cancer progression through EMT inhibition and induction of ER stress
… cancer cell invasion and the mechanism of EMT inhibition (Chapter 4). C150 exhibited well-separated cytotoxicity between pancreatic cancer cells and non-cancerous cells. The IC50 values were 1~2.5 mM in multiple pancreatic cancer cell lines and 12.5 mM in non-cancerous pancreatic epithelial …
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Inhibition of the Toxoplasma gondii replication by inhibition of the mitochondrial respiratory chain
… ist. Vermutlich kommt es hierbei zu einer Inhibition des Ubiquinon/Ubiquinol-Kreislaufs an der Reduktionsseite durch HDQ und an der Oxidationsseite durch Atovaquon. Die Behandlung von T. gondii mit HDQ und dem Komplex-III-Inhibitor Antimycin A ist tendenziell additiv und unterscheidet sich …
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Visual-tactile stop signal inhibition
This study investigated voluntary inhibition of programmed movements upon infrequent presentation of visual or tactile stop signals. Participants were to perform fast saccadic or manual responses to a visual or tactile target, but to cancel the response on the 25% of trials in which a stop signal …
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Nucleotide Inhibition of Glyoxalase II
… that the purified enzyme remains "sensitive" to inhibition by ATP or GTP (Glo-II-s). Studies indicate that inhibition of Glo-II-s by nucleotides is restricted to ATP, GTP, ADP, and GDP, with ATP appearing most effective. Kinetics studies have shown that ATP acts as a partial non-competitive …
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Chemical Approaches to Dynein Inhibition
… dynapyrazoles). An analysis of the mechanism of inhibition of dynein 1 by dynapyrazole A revealed that it inhibited the microtubule-stimulated ATPase activity of dynein, but did not potently inhibit the basal ATPase activity. This finding and further biochemical analyses revealed that …
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Surfactant aspects of corrosion inhibition
… the surfactant aspects of corrosion inhibition. Corrosion inhibitors are of great industrial importance because they are a relatively inexpensive and easily applicable method of protecting oil pipelines against internal corrosion. The performance of corrosion inhibitors is known to …
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Inhibition in long-term memory
… within the retrieval practice paradigm, in which inhibition is recruited against information that competes for memory access during retrieval, and within the list-method directed forgetting paradigm, in which inhibition is voluntarily recruited.Experiments 1-8, with a total of 315 participants …
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Response Stereotypy and Retroactive Inhibition
Made available in DSpace on 2014-12-03T23:50:40Z (GMT). No. of bitstreams: 1 0010541.pdf: 2392340 bytes, checksum: 1bdc2bd5a854c583442cfa3ec2e3b0ce (MD5) Previous issue date: 1954
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INHIBITION OF THE SERINE PROTEASE CHYMOTRYPSIN BY A SILANEDIOL PEPTIDE MIMIC: ASYMMETRIC SYNTHESIS AND INHIBITION STUDIES
… of amide hydrolysis and have shown outstanding inhibition of metallo and aspartic proteases. This research describes the synthesis and inhibition of the serine protease α- chymotrypsin by silanediol structures and the development of an efficient method to install the stereochemistry at the P1’ …
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Serotonin and Norepinephrine in Latent Inhibition.
… affected subjects* performance in the latent inhibition paradigm. This evidence was correlated with earlier work which showed norepinephrine depletions attenuating performance in blocking, whereas serotonin-depleted rats behaved like normals in the paradigm. Thus, different neurochemicals are …
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Proteasome inhibition in chronic myeloid leukaemia
… susceptible. Bortezomib is associated with inhibition of proteasome activity, however that of BCR-ABL appears unaffected. Significant synergy is seen when bortezomib and dasatinib are used in combination. We also demonstrate that bortezomib is effective in inhibiting proteasome activity and …
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Tau Aggregation, Conformational Selection, and Inhibition
… 4R Tau fibril end. This could account for the inhibition via disruption of the ability of Tau to subsequently bind to the capped fibril end. MAP2 inhibition of Tau fibril formation and progression could be a natural modulator of the fibril spreading in the brain.</p>
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Coronavirus Replication Inhibition by Herbal Extracts
… was analyzed by plaque assay. The replication inhibition of MHV by herbal extracts in terms of RNA replication was explored through the analysis of the intracellular viral RNAs. Plaque assay results showed that some of the herbal extracts inhibited coronavirus replication. Northern blot …
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In vitro inhibition of coronavirus replications
"In Vitro Inhibition of Coronavirus Replications A search for new anti-coronaviral drugs to treat coronaviral infections was motivated by an outbreak of severe acute respiratory syndrome (SARS). In order to find drugs that treat coronavirus infections, including SARS, we screened traditional …
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