Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 92 for “"inflammatory processes"”.
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Inflammatory processes and risk of cancer: epidemiological research.
… whether elderly women (65+) suffering from an inflammatory autoimmune disease - psoriasis - have an increased risk of total, breast, lung, or colon cancers in the IWHS cohort linked to Medicare. We observed an association between psoriasis and colon cancer risk: multivariate-adjusted HR=1.57 …
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Nucleobase deamination as a biomarker of inflammatory processes
(cont.) kinetic studies. Moderate increases ([approximately]30%) in nucleobase deamination products were observed in the SJL mice bearing the RcsX tumor, but the biological meaning of these increases awaits studies of DNA repair kinetics. dO was not detected in any study at levels above 5 per 10⁸ …
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Identifying dietary additive regulated mechanisms impacting intestinal epithelial cell responses and inflammatory processes
… and management of gastrointestinal diseases like Inflammatory Bowel Disease (IBD). Dietary influences are now considered significant in determining an individual's susceptibility to IBD, yet much remains unknown about the long-term effects of various dietary components. The main objective of my …
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Long COVID related inflammatory processes. What is its impact on bone, joints and musculoskeletal microvascular haemodynamics?
… Additionally, it aims to examine the role of inflammatory markers as potential etiological factors, assess health-related quality of life, and consider the contribution of inflammatory mechanisms to physiological changes. Methods: This study combined a systematic literature review with a …
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The Cannabinoid-2 Receptor Agonist O-1966 Reverses Postischemic Learning and Memory Deficits Through Anti-Inflammatory Processes
… to examine the potential efficacy of the anti-inflammatory Cannabinoid-2 Receptor Agonist, O-1966, in attenuating infarct expansion and reversing cognitive deficits in the subacute phase of the disease using a photothrombosis model of stroke. Additionally, we sought to characterize the …
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A New Role for Beta-Amyloid in Alzheimer's Disease: Initiation of Thrombotic and Inflammatory Processes Via Coagulation Factor XII and Fibrinogen
… of disease is debated. Prothrombotic and inflammatory states can contribute to alterations in cerebral blood flow resulting in hypoperfusion. Since neuronal function is dependent on an uninterrupted blood supply sustained by a healthy vasculature, agents capable of eliciting thrombosis …
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Die Untersuchung zellulärer inflammatorischer Prozesse bei Pseudoxanthoma elasticum
… The SASP is associated with high production of inflammatory factors, such as interleukin 6. The molecular mechanism leading to inflammatory processes in PXE are not fully understood. Thus, this study was designed to analyze different molecular aspects and inflammatory signaling pathways in ABCC6 …
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Aetiologie, Klinik und Prognose bei männlichen Rindern mit Harnröhrenverschluss
… of the stage of the disease and the detection of inflammatory processes. Initially a sawhorse stance, agitation and colic were prominent, whereas animals in the advanced stage became weak and recumbent; some of them did so after a transient period of apparent improvement of their general …
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LONG-LASTING MOLECULAR ALTERATIONS FOLLOWING EARLY LIFE STRESS IN RATS: ROLE OF GUT MICROBIOTA AND INFLAMMATION
… exposures. The presence of a chronic low-grade inflammatory status has been suggested to play a central role, however, a better knowledge of the inflammatory processes, as well as of the neurodevelopmental temporal window where such alterations become manifested, is still needed. Moreover, among …
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Validation of magnetic resonance imaging (MRI) as a tool to detect inflammation in the brain
… tools that can reliably measure these inflammatory processes in patients. The primary aim of this thesis was to develop and validate MRI tools for measurement of neuroinflammation. Twenty healthy volunteers participated in a randomised double-blind, placebo-controlled, crossover study …
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The role of endotoxin receptors toll-like receptor 4 and lipopolysaccharide-binding protein in Mycobacterium tuberculosis infection
… infection? What role do these PRRs play in inflammatory processes and in the development of granuloma? What role do the PRRs play in driving cytokine and chemokine response? Specifically, the following mice were infected aerogenically with Mtb H37Rv to further investigate their roles in vivo …
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Verificação da hipótese auto-imune da esquizofrenia com técnicas e aportamento molecular
… to which schizophrenia could be due to an inflammatory process of the central nervous system. The objective of this work is to verify the interaction of neurotransmitters that are normally involved in inflammatory processes (Interleukin-6) and those that are responsible for metabolizing …
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UNVEIL THE CONNECTION BETWEEN METABOLIC AND INFLAMMATORY CARDIOVASCULAR RISK FOSTERED BY NUTRIENT INTAKES.
… Therapeutic strategies targeting the residual inflammatory risk (increased levels of inflammatory markers) effectively further reduced ACVD incidence. On the other hand, therapeutic strategies to contain the residual metabolic risk (increased TGRL) provided discordant results. Recent evidence …
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Association Between Fluoride Exposure and Immune System Biomarkers in Pregnancy
… suggesting fluoride may be implicated in inflammatory processes during the third trimester. Further characterization of the timing of maternal immune activation is needed to advance our understanding of critical vulnerability periods during pregnancy.
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Markers of immunosenescence and oxidative stress in healthy adults
… facilitate immune surveillance, or aggravate inflammatory processes. Second, CMV was seen to drive the development of an ‘Immune Risk Profile’ in young adults, characterised by increased inflammatory activity and smaller responses to vaccination. These outcomes are associated with frailty, …
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Relationship of Anger Trait and Anger Expression to C-Reactive Protein in Post-Menopausal Women
… such as anger, may be associated with pro-inflammatory processes that contribute to cardiovascular morbidity and mortality in women. The purpose of this study was to determine if there were differences in serum levels of the proinflammatory biomarker, C-reactive protein, in post-menopausal …
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The physicochemical characterisation of cyclodextrin inclusion compounds with non-steroidal anti-inflammatory drugs
… of varying number. The non-steroidal anti-inflammatory drugs (NSAIDs), a group of agents that share a similar therapeutic effect in the management of inflammatory processes in the body, have been studied as guest molecules for inclusion in cyclodextrins, due to a number of potential …
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The Effects of Chronic Prophylactic Naproxen Sodium on Skeletal Muscle Adaptation to Resistance Exercise in Recreationally-Trained College-Aged Males
… muscle injury (EIMI), triggering an acute local inflammatory response associated with delayed-onset muscle soreness (DOMS). DOMS is characterized by a predictable discomfort and decreased level of muscle performance and is believed to be the product of both mechanical and inflammatory processes. …
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Endogenous Mechanisms Regulating Myeloid Cell Mediated Inflammation During Acute Lung Injuries
… of Histone H3 to silence the expression of inflammatory cytokines. In the second approach, we demonstrate that the neuronal guidance protein, Netrin-1, is highly expressed in infiltrating alveolar macrophages after the onset of ALI. Netrin-1 deletion in the myeloid compartment resulted in …
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The Role of Dysfunctional Na+/H+ Exchange in the Development of Dysbiosis and Subsequent Colitis
… be accounted for by genetics alone. Among those, Inflammatory Bowel Disease (IBD) has risen from a western disease affecting industrialized populations to an emerging global threat affecting diverse populations around the world. IBD is a complex disease that combines genetic susceptibility and …
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