Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 230 for “"inflammatory diseases"”.
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Immunological mechanisms controlling chronic inflammatory diseases
Autoimmune diseases (AID) are chronic inflammatory diseases (CID) mediated by self-reactive T and B cells and are generally the results of the breakdown of T cell tolerance to self-antigen and failure of peripheral regulatory mechanisms. In this thesis I studied different mechanisms controlling the …
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Theranostic nanoparticles for the management of inflammatory diseases and conditions
… arteries, is the main cause of cardiovascular diseases (CVDs). The World Health Organization reports that CVDs are the number one cause of death in the world. In the United States alone, around 85 million people suffer from CVDs; this is associated with a cost of over $316 billion per year and …
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The role of IL-27 and IL-35 in inflammatory diseases
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by chronic inflammation within the synovial tissues in multiple joints leading to progressive, erosive destruction of cartilage and underlying joints. The severity of RA is associated with the overexpression of …
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Preclinical evaluation of a vaccine against IL-17 mediated inflammatory diseases including psoriasis
… condition. Interleukin 17A (IL-17A) is a pro-inflammatory cytokine with a key role in the pathogenesis of this disease. Antibodies targeting IL-17A have shown superior efficacy compared with other psoriasis treatments, and long-term studies have demonstrated these to be safe in humans. …
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Aggregation, Spatio-Temporal Structures and Well-Posedness in Chemotaxis Models of Inflammatory Diseases
L'infiammazione è la risposta immunitaria dell'organismo a uno stimolo nocivo. Il suo scopo è prevenire l'insorgere di malattie. Sebbene sia un meccanismo protettivo, un disordine della risposta infiammatoria può portare a malattie gravi e debilitanti, come la sclerosi multipla. Per questo …
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The Epidemiology and Patient Perspectives of Glucocorticoid Use in Rheumatoid Arthritis and Other Inflammatory Diseases
… the benefits and harms of GC treatment in inflammatory rheumatic diseases, with an emphasis on rheumatoid arthritis (RA). The introduction summarises inflammation as a normal physiological process, and its contribution to chronic inflammatory diseases, commonly treated with GCs. It further …
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Macrophage COX-2 As a Target For Imaging And Therapy of Inflammatory Diseases Using Theranostic Nanoemulsions
… address the unsatisfactory treatment outcomes in inflammatory conditions such as cancer, arthritis, and cardiovascular diseases. A common feature of chronic diseases is the infiltration of pro-inflammatory macrophages at the disease loci. Infiltrating macrophages have been previously utilized for …
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Macrophage COX-2 As a Target For Imaging And Therapy of Inflammatory Diseases Using Theranostic Nanoemulsions
… address the unsatisfactory treatment outcomes in inflammatory conditions such as cancer, arthritis, and cardiovascular diseases. A common feature of chronic diseases is the infiltration of pro-inflammatory macrophages at the disease loci. Infiltrating macrophages have been previously utilized for …
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Construction and Performance Optimization of Bioconjugated Nanosensors for Early Detection of Breast Cancer and Pro-inflammatory Diseases
… as optical nanosensors for cancers and metabolic diseases. Breast cancer and cardiovascular diseases are the most common causes of death in the USA. Time-consuming clinical procedures limit the current screening tests for both diseases. Early diagnosis of these diseases significantly improves the …
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Comparison of Treatment Methods for Chronic Periapical Inflammatory Diseases // Сравняване на методи за лечение на хронични периапикални възпалителни заболявания
… and their toxins; to influence the inflammatory process in the periapical tissues and to stimulate the healing process; to provide an airtight filling of the root canal to isolate the apical periodontium from contact with saliva in the oral cavity. The removal of the etiological …
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EVALUATION OF THE OXIDATIVE METABOLITES OF ARACHIDONIC ACID AND THEIR IMPLICATION IN THE PROGRESSION OF INFLAMMATORY DISEASES: HYPERTENSION AND RHEUMATOID ARTHRITIS
Inflammation is implicated in diseases such as hypertension and rheumatoid arthritis (RA). A mechanistic understanding of inflammatory processes as it relates to the disease state and injury needs to be developed. Specifically, the role and modulation of inflammation needs to be assessed, as well …
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ADP-Heptose and Nucleotide Enhancers Drive Fusobacteria-Induced Inflammation
… <em>Fusobacteria</em> is associated with diverse inflammatory diseases and cancers, but the underlying molecular mechanisms that drive these associations remain elusive. Here I report studies showing that among commensal bacteria, <em>Fusobacteria</em> are uniquely potent activators of nuclear …
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Hypoxic Influences On Myeloid Cells During Inflammation And Inflammation-Associated Cancer
… characteristic of many acute or chronic inflammatory diseases, and exerts significant influence on their progression. Macrophages and neutrophils are major cellular components of innate immunity and contribute not only to O2 deprivation at the site of inflammation, but also alter many of …
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Characterization of Biomedical and Incidental Nanoparticles in the Lungs and Their Effects on Health
… to administer therapeutic nanoparticles. Indeed, inflammatory diseases such as asthma and emphysema could potentially benefit from nanoparticle-mediated delivery. However, the lungs are also in constant contact with airborne particulate matter. Thus, harmful nanoparticles can enter the lungs and …
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