Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 105 for “"inflammatory cells"”.
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The Effects of Synovial Fluid and Inflammatory Cells on Orthopaedic Implant Alloys
… placed into 24 well plates. After seeding the cells, the culture medium was replaced every 24 hours, and the supernatant fluid was collected every day starting on the second day of the experiment. After 30 days, cells were removed from the surface of the alloy specimens, counted, tested for …
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Studies on the Cellular Responses and Roles of Microglia, Astrocytes, and Blood-Derived Inflammatory cells in Injured Rat Brain
… nor monocytes expressed iNOS, a major neurotoxic inflammatory mediator. Monocytes rather expressed CD68, a marker of phagocytic activity. Importantly, the total number of dopaminergic neurons in the SNpc at 3 h (~80% of that in the contralateral side) did not decrease further at 7 d. Similarly, in …
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A comparative analysis of cowpox virus (CPV WT) and a deletion mutant lacking the gene encoding the inflammation modulatory protein (CPV IMP)
… of virus, antibody-mediated lysis of infected cells and migration of inflammatory cells into the site of infection. VCP also possesses heparin binding sites.
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Specificity protein 1 induces the expression of angiomotin in response to IL-6/STAT3 activation to mediate YAP-dependent growth of breast cancer cells
… fifty percent of breast cancers. Tumors activate inflammatory processes by secreting factors that recruit and trigger inflammatory cells to release cytokines such as Interleukin 6 (IL-6). IL-6 stimulates the activity of signal transducers and activators of transcription 3 (STAT3), a transcription …
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The effect of Stromal cell Derived Factor-1 (SDF-1) and collagen-GAG (Glycosaminoglycan) scaffold on skin wound healing
… evidence also suggests that down-regulating inflammatory cells and up-regulating stem cells and progenitors cells would yield less scar formation. But, these therapies require an expensive isolation and culturing process from the patient's bone marrow. Additional risks include immune …
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Targeting macrophages GLP-1 receptor pathways as emerging therapies to ameliorate cardiac remodelling associated with diabetes
… prominent in diabetes. Hence, targeting inflammatory pathways may have direct benefit in treatment of cardiovascular disease in diabetes. Glucagon-like peptide (GLP-1) is an incretin hormone, which confers proven glycaemic control in diabetes, and also demonstrates cardioprotective …
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Advanced glycation end product precursors in diabetes: a crucial link between oxidative stress and inflammation?
… that GO and MG are pro-oxidant and pro-inflammatory at (patho)physiological concentrations in both monocytes and pancreatic β-cells.<br/><br/>In this work several new and important observations have been made regarding the action of α-dicarbonyls on oxidative stress and inflammation. 1) …
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Soy Isoflavones Mediate Radioprotection Of Normal Lung Tissue By Modulating The Radiation-Induced Inflammatory Response
… lung injury (RILI) is caused by an early inflammatory process triggered by damage to lung parenchyma, epithelial cells, vascular endothelial cells and stroma. Initially, oxidative injuries after radiation induce altered expression of pro-inflammatory cytokines. Infiltrating inflammatory …
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TRAIL and TGF-ßl-Induced Apoptosis of Human Airway Epithelial Cells
Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness (AHR), airway obstruction, wheezing, and leads to airway remodeling if these symptoms persist. Airway remodeling is characterized by goblet hyperplasia, airway smooth muscle hypertrophy and hyperplasia, …
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Imaging atherosclerotic plaque inflammation with [18F]- fluorodeoxyglucose positron emission tomography
… of atherosclerosis. Plaques containing numerous inflammatory cells, particularly macrophages, have a high risk of rupture, whereas those with fewer inflammatory cells are at lower risk. The current ‘gold standard’ technique for imaging atherosclerosis is x-ray contrast angiography, which provides …
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ΑΝΟΣΟΙΣΤΟΧΗΜΙΚΗ ΚΑΙ ΜΟΡΦΟΛΟΓΙΚΗ ΜΕΛΕΤΗ ΤΩΝ ΚΑΡΚΙΝΩΜΑΤΩΝ ΣΤΟΜΑΧΟΥ ΚΑΙ ΕΝΤΕΡΟΥ
… CONSEQUENCE OF PHENOTYPIC INSTABILITY OF CANCER CELLS. A MINIMAL CORRELATION WAS FOUND BETWEEN THE HLA-DR EXPRESSION AND THE INFLAMMATORY CELLS. THE INDEX K1 67 WAS NOT FOUNDANY CORRELATION WITH PROGNOSIS THESE TYPES OF CARCINOMAS. CALLA EXPRESSION ININTESTINAL METAPLASIA COULD BE CONSIDERED AS …
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TRAIL mediated apoptosis in arthritis.
… in cell accumulation and prolonged half life of inflammatory cells in rheumatoid arthritis (RA). A similar phenomenon is seen in malignancy. Therefore, defects in apoptosis pathways that have been proposed to contribute to the pathogenesis of malignancy may also be seen in RA. It has been …
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TLR4 endogenous ligand S100A8/A9 levels in adult-onset Still’s disease and their association with disease activity and clinical manifestations
… Peripheral blood mononuclear cells (PBMC) from active AOSD and HC were evaluated for IL-1β release, and in vitro study with PBMC and THP-1 cell line was done for cell signal of S100A8/A9. Results: Serum S100A8/A9 in AOSD patients was higher than those of RA patients and HC. …
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Correlation between Locally Produced Specific IgA and Eosinophil Cationic Protein in Nasal Lavage Fluids of Allergic Rhinitis Patients during Allergen Provocation Tests
"Background: Eosinophils are the major effector cells in nasal allergic inflammation. However, the mechanism of eosinophil activation mediated by a series of inflammatory mediators presenting in early and late responses of allergic rhinitis (AR) is not fully understood. Objective: The aim of this …
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Adaptive immune responses in atherosclerosis - or how to prolong the use of your yellow socks
… essential component of cellular membranes, and inflammatory cells at the injury site. Since cholesterol particles are not normally accumulating extra-cellularly, they are affected by the inflammatory environment, which modifies the particle structure. Since this can be potentially dangerous an …
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Characterization of Pleiotropic Activities of alpha1-Antitrypsin
… a respiratory disease characterized by chronic inflammatory response in the airways and lung parenchyma that involves the influx of inflammatory, structural cells and mediators. The inflammatory process resulting in lung tissue destruction, emphysema, includes the excess of uninhibited proteases …
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Exosome Prevention of Post Operative Atrial Fibrillation
… (EVs) isolated from human atrial explant-derived cells can prevent post-operative AF. Middle-aged female and male rats were randomized to undergo sham operation or induction of sterile pericarditis followed by trans-epicardial injection of human EVs or vehicle into the atrial tissue. Pericarditis …
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The expression profile of cytoglobin in human fibrotic lung, and the protective role of cytoglobin in hypoxia and oxidative stress in vitro
… here is evidence of CYGB expression within cells of fibrotic lesions taken from patients with Idiopathic Pulmonary Fibrosis (IPF) and Chronic Obstructive Pulmonary Disease (COPD). CYGB staining was observed in fibroblasts, endothelial cells, type II pneumocytes, type I pneumocytes, …
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Astrocytes down-regulate microglial inflammatory responses
Microglia, the major inflammatory cells in the brain, are activated in injured brain and produce several inflammatory mediators. Previously, it has been reported that soluble factors from cultured astrocytes are capable of suppressing microglial activation. However, brain injury affect not only …
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BMPR2 and mTOR Signaling Pathways in Inflammatory Lung Diseases
… IgE, airway hyperreactivity (AHR), inflammatory cells, and mucus-producing goblet cells. When rapamycin was administered after systemic sensitization, but just prior to allergen exposure to the lung, many key responses including increases in IgE, AHR, goblet cells, lung T cells, and …
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