Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 50 for “"inflammatory biomarkers"”.
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Inflammatory Biomarkers, Genetics, and Survival among Colorectal Cancer Patients
… regarding the connection between circulating inflammatory biomarkers and CRC prognosis is limited to C-reactive protein (CRP) and interleukin (IL)-6. However, other inflammatory biomarkers with biologic relevance, such as monocyte chemoattractant protein-1 (MCP-1), adiponectin, and leptin, are …
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Polyunsaturated fatty acids and inflammatory biomarkers in the pathogenesis of type II diabetes
… studies have reported elevated levels of pro-inflammatory cytokines (IL-6, TNF-α, MCP-1, IL-1β) and different fatty acid (FA) patterns are associated with type 2 diabetes mellitus (DM2). In addition, an association of hypovitaminoses D with DM2 has been observed in some populations. No study …
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Physical activity, sedentary behaviour, physical fitness and inflammatory biomarkers in children and adolescents
… of new CVD risk factors, among which are the inflammatory biomarkers(9). The overall objective of the present doctoral thesis was to study the influence of the physical activity, sedentary behaviour and physical fitness levels as well as the neck circumference on emerging CVD risk factors in …
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Effect of omega-3 polyunsaturated fatty acids on inflammatory biomarkers in chronic obstructive pulmonary disease
… disease (COPD) is a chronic progressive inflammatory disease characterised by airflow limitation. Several pro-inflammatory markers are thought to be involved in the pathogenesis of COPD. Cigarette smoking is a major risk factor for COPD, and diet may be a modifiable risk factor for its …
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Benefits of Quercetin on Metabolic and Inflammatory Biomarkers in High Fat Diet Induced Obesity: A Dose Response Study
<p>Obesity is a chronic low-grade inflammatory disease that can lead to a variety of health complications including coronary heart disease, type 2 diabetes, hypertension, degenerative diseases and a wide array of cancers. For this reason, dietary supplements with anti-inflammatory properties have …
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DHA-rich fish oil and regular moderate exercise: a combined intervention to improve cardiovascular, metabolic and inflammatory biomarkers in obesity.
… regular moderate exercise, on CV, metabolic and inflammatory biomarkers. Sedentary, overweight volunteers (BMI > 25kg/m2) with mild hypertension (140/90 – 160/100mmHg), elevated plasma triglycerides (TAG) (>1.6mmol/L) or elevated total cholesterol (TC) (>5.5mmol/L) were recruited in three cohorts …
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Effects of S-adenosyl-L-methionine (SAMe) supplementation on systemic oxidative stress and inflammatory biomarkers of adult dogs undergoing stress challenges
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01
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Investigating the Role of Inflammatory Biomarkers and Incretins in the Aetiology of Type 2 Diabetes and Coronary Heart Disease using Human Genetics
Background: The relevance of inflammatory and incretin-related signalling pathways in the aetiology of cardiometabolic diseases is of considerable pharmacological interest but remains uncertain. Evidence from animal models and epidemiological studies point to a role for chronic inflammation for the …
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IMPACT OF INDOOR AIR POLLUTION ON INFLAMMATORY BIOMARKERS AND CARDIAC AUTONOMIC CONTROL IN HEALTHY SUBJECTS AND PATIENTS WITH CONGESTIVE HEART FAILURE (APICE STUDY)
… control (CAC) during sleep and of systemic inflammatory profile associated with exposure to indoor air pollution (IAP) in healthy subjects and patients affected by chronic heart failure (HF). Twenty healthy volunteers and nineteen HF patients were enrolled. Indoor levels of fine particulate …
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Analysis of Dietary Intake, Body Composition and Biomarkers in Adults with Type 2 Diabetes Mellitus, Prediabetes and Without Diabetes
… values, dietary intake, body composition, and inflammatory markers (high sensitivity-C-reactive protein (HS-CRP), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6)) between adults with type 2 diabetes mellitus (T2DM) and prediabetes (PDM) to adults without diabetes. A total of 22 …
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Inflammation and neutrophil recruitment in ageing subjects and patients with chronic obstructive pulmonary disease
… correlations were demonstrated between the inflammatory biomarkers and between inflammatory biomarkers and markers of disease. IL-8 correlated most strongly both with other inflammatory mediators, neutrophil counts and indices of disease. Neutrophils from healthy older subjects migrated with …
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Childhood Maltreatment is Associated with Adult Depression: Is Inflammation to Blame?
… that adversity and social threat upregulate pro-inflammatory biomarkers leading to depression. The current study examined whether pro-inflammatory biomarkers (interleukin-6, interleukin-8, c-reactive protein, and tumor necrosis factor alpha) mediate the association between various types of …
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Blood-Based Inflammation Biomarkers of Neurocognitive Impairment in People Living with HIV
… in a demographically balanced cohort of PLWH. Inflammatory biomarkers of HIV-associated neurocognitive impairment could improve current diagnosis methods and may be specific for populations disproportionately affected by the HIV. Seven neurocognitive domains were evaluated in 121 seropositive …
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Mapping Ultrasound Features of Hand Osteoarthritis: Links to Classifications, Clinical Signs, and Self-Reported Outcomes
… for detecting early OA features, particularly inflammatory changes; however, the interplay between US-detected abnormalities, systemic inflammatory activity, clinical signs, and self-reported symptoms is not fully understood. This thesis aimed to: (1) map the anatomical distribution of …
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Clinical, Metabolic and Inflammatory Indicators of Esketamine Efficacy for Treatment-Resistant Major Depressive Episodes
… and elevated suicide risk. Metabolic and inflammatory abnormalities may contribute to inadequate response to treatments. Esketamine has demonstrated promise in TRD, but its biological effects and predictors of response remain poorly understood. This study examined clinical outcomes and …
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Hempseed oil as a novel source of polyunsaturated fatty acids and its effect on inflammation in sedentary horses
… fatty acids (PUFA) play a role in mitigating the inflammatory response and are therefore explored as a dietary approach to attenuate inflammation. γ-Linolenic acid (GLA) is a unique PUFA that when supplemented in the diet can increase the production of anti-inflammatory eicosanoids; however, it is …
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TNF inhibitors for the prevention of Alzheimer’s disease
… in rheumatoid arthritis (RA), a chronic inflammatory autoimmune disease, as these patients have higher levels of systemic inflammation than the general population. If AD is driven by inflammation, then RA may be the ideal model in which to observe the accelerated effects of systemic …
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Investigating The Role Of Transient Receptor Potential Ankyrin One (TRPA1) In Cardiovascular Regulation
… in TRPAl KO mice. Further analysis of associated inflammatory biomarkers by RT qPCR and MSD multiplex ELISA showed upregulation of pro-oxidative genes in hypertensive mice of both genotype. This was significantly greater in hypertensive TRPAl KO mice than in hypertensive TRPAl WT mice.<br/>These …
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